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「an oral beta blocker (trade name Sectral) used in treating hypertension」

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/10/28 02:53:15」(JST)

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  • Peripheral vasoconstriction induced by beta-blockers: a systematic review and a network meta-analysis.
  • Khouri C1, Jouve T2, Blaise S3,4,5, Carpentier P5, Cracowski JL2,3,4, Roustit M2,3,4.
  • British journal of clinical pharmacology.Br J Clin Pharmacol.2016 Apr 16. doi: 10.1111/bcp.12980. [Epub ahead of print]
  • AIM: Peripheral vasoconstriction has long been described as a vascular adverse effect of beta-blockers. Whether beta-blockers should be avoided in patients with peripheral vascular disease depends on pharmacological properties (e.g. preferential binding to β1-adrenoreceptors or intrinsic sympathomi
  • PMID 27085011
  • Development of SPME-LC-MS method for screening of eight beta-blockers and bronchodilators in plasma and urine samples.
  • Goryński K1, Kiedrowicz A2, Bojko B3.
  • Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2016 Mar 4. pii: S0731-7085(16)30119-4. doi: 10.1016/j.jpba.2016.03.001. [Epub ahead of print]
  • The current work describes the development and validation of a simple, efficient, and fast method using solid phase microextraction coupled to liquid chromatography-tandem mass spectrometry (SPME-LC-MS/MS) for the concomitant measurement of eight beta-blockers and bronchodilators in plasma and urine
  • PMID 26971030
  • Aqueous chlorination of acebutolol: kinetics, transformation by-products, and mechanism.
  • Khalit WN1, Tay KS2.
  • Environmental science and pollution research international.Environ Sci Pollut Res Int.2016 Feb;23(3):2521-9. doi: 10.1007/s11356-015-5470-y. Epub 2015 Oct 1.
  • This study investigated the reaction kinetics and the transformation by-products of acebutolol during aqueous chlorination. Acebutolol is one of the commonly used β-blockers for the treatment of cardiovascular diseases. It has been frequently detected in the aquatic environment. In the kinetics stu
  • PMID 26423291


  • Involvement of influx and efflux transport systems in gastrointestinal absorption of celiprolol
  • Kato Yukio,Miyazaki Tatsuya,Kano Takashi,Sugiura Tomoko,Kubo Yoshiyuki,Tsuji Akira
  • Journal of Pharmaceutical Sciences 98(7), 2529-2539, 2009-07
  • … Interestingly, OATP-A/1A2 accepts various b-blockers including acebutolol, atenolol and sotalol, oral absorption of which is inhibited by coadministration of citrus juice or telithromycin in human. …
  • NAID 120001451016
  • Using supported liquid extraction together with cellobiohydrolase chiral stationary phases-based liquid chromatography with tandem mass spectrometry for enantioselective determination of acebutolol and its active metabolite diacetolol in spiked human plasma
  • JIANG Hongliang,RANDLETT Christopher,JUNGA Heiko,JIANG Xiangyu,JI Qin C.
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 877(3), 173-180, 2009-01-15
  • NAID 10028011872
  • Spectrofluorimetric Determination of Drugs Containing Active Methylene Group Using N^1-Methyl Nicotinamide Chloride as a Fluorigenic Agent
  • El Dawy Mohamed Abdelfattah,Mabrouk Mokhtar Mohamed,El Barbary Riad Ahmed
  • Chemical & pharmaceutical bulletin 54(7), 1026-1029, 2006-07-01
  • … The method was applied successfully to the determination of three life saving cardiovascular drugs, with narrow therapeutic indices: pentoxifylline (I), propafenone hydrochloride (II) and acebutolol hydrochloride (III), in laboratory-prepared mixtures, in commercial tablets and in plasma samples. …
  • NAID 110004836428




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acebutolol hydrochloride」