abarelix

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/11/27 18:24:57」(JST)

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英文文献

  • Utility of LHRH antagonists for advanced prostate cancer.
  • Moul JW1.
  • The Canadian journal of urology.Can J Urol.2014 Apr;21(2 Supp 1):22-7.
  • INTRODUCTION: Androgen deprivation therapy (ADT) is the lynchpin of treatment for advanced prostate cancer. Prescribing physicians and patients have a choice between orchiectomy, luteinizing hormone releasing hormone (LHRH) agonists, combined androgen deprivation (CAD) or LHRH antagonists.MATERIALS
  • PMID 24775720
  • Effects of GnRH antagonists vs agonists in domestic carnivores, a review.
  • Gobello C1.
  • Reproduction in domestic animals = Zuchthygiene.Reprod Domest Anim.2012 Dec;47 Suppl 6:373-6. doi: 10.1111/rda.12025.
  • Gonadotrophin-releasing hormone (GnRH) stimulates the pituitary secretion of both luteinizing and follicle-stimulating hormones, and thus controls the hormonal and reproductive functions of the gonads. GnRH analogs, which include agonists and antagonists, have been produced by amino acid substitutio
  • PMID 23279542
  • New treatment paradigm for prostate cancer: abarelix initiation therapy for immediate testosterone suppression followed by a luteinizing hormone-releasing hormone agonist.
  • Garnick MB1, Mottet N.
  • BJU international.BJU Int.2012 Aug;110(4):499-504. doi: 10.1111/j.1464-410X.2011.10708.x. Epub 2011 Nov 16.
  • Study Type - Therapy (prospective cohort). Level of Evidence 2a. What's known on the subject and What does the study add The sequential administration of a GnRH antagonist followed by an LHRH agonist in the management of prostate cancer patients has not been studied, but such a program would provi
  • PMID 22093775

和文文献

  • Abarelix Study Group. An open-label study of abarelix in men with symptomatic prostate cancer at risk of treatment with LHRH agonists

関連リンク

InChI=1S/C72H95ClN14O14/c1-41(2)32-54(64(93)80-53(17-10-11-30-77-42(3) 4)72(101)87-31-13-18-60(87)69(98)78-43(5)63(75)92)81-68(97)58(38-62(74)91 )84-70(99)61(37-46-22-27-52(90)28-23-46)86(7)71(100)59(40-88)85-67(96)57  ...
2003年11月25日 ... ・FDA は進行性前立腺癌に対する新薬[Plenaxis](abarelix)を承認 〔米 FDA〕・・・・・・・ ・・・・・・・・p.1. ・FDA は Cordis 社 ... FDA は,代替治療のない進行性前立腺癌患者 に対する医薬品,[Plenaxis](abarelix)の販売を許. 可する NDA(新薬 ...

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AbarelixSome people receiving an abatacept Abarelix-PlenaxisSide Effects Of AbarelixAbarelix.svgEffects of LH on the body


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