"In the 19th century, surgeon Julius Wolff proposed that mechanical stress was responsible for determining the architecture of bone...." (Forwood & Turner, 1995, p. 197). (資料2)
"Remodeling of bone ... occurs in response to physical stresses - or to the lack of them - in that bone is deposited in sites subjected to stress and is resorbed from sites where there is little stress" (Salter, 1970, p.7). (資料2)