関: Uridine diphosphate glucose

WordNet

the 21st letter of the Roman alphabet (同)u
a monosaccharide sugar that has several forms; an important source of physiological energy

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uraniumの化学記号
上流の,上流階級にふさわしい / (映画が)児童観覧用の
ブドウ糖

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/02/05 21:49:45」(JST)

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Uridine diphosphate glucose (uracil-diphosphate glucose, UDP-glucose) is a nucleotide sugar. It is involved in glycosyltransferase reactions in metabolism.

Functions[edit]

It is used in nucleotide sugars metabolism as an activated form of glucose as a substrate for enzymes called glucosyltransferases.^[1]

It is a precursor of glycogen and can be converted into UDP-galactose and UDP-glucuronic acid, which can then be used as substrates by the enzymes that make polysaccharides containing galactose and glucuronic acid.

UDP-glucose can also be used as a precursor of sucrose lipopolysaccharides, and glycosphingolipids.

Components[edit]

UDP-glucose consists of the pyrophosphate group, the pentose sugar ribose, glucose, and the nucleobase uracil.

References[edit]

^ Rademacher T, Parekh R, Dwek R (1988). "Glycobiology". Annu Rev Biochem 57: 785–838. doi:10.1146/annurev.bi.57.070188.004033. PMID 3052290.

UpToDate Contents

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1. 成人糖尿病患者のマネージメントにおける血糖の自己モニタリング（SMBG） blood glucose self monitoring in management of adults with diabetes mellitus
2. 乳児および小児における低血糖に対するアプローチ approach to hypoglycemia in infants and children
3. 糖尿病における血糖コントロールの評価 estimation of blood glucose control in diabetes mellitus
4. グルコース-6-リン酸脱水素酵素欠損症の診断とマネージメント diagnosis and management of glucose 6 phosphate dehydrogenase deficiency
5. 2型糖尿病のスクリーニング screening for type 2 diabetes mellitus

English Journal

Silencing UDP-glucose pyrophosphorylase gene in Phaeodactylum tricornutum affects carbon allocation.

Zhu BH1, Shi HP2, Yang GP3, Lv NN2, Yang M2, Pan KH4.
New biotechnology.N Biotechnol.2016 Jan 25;33(1):237-44. doi: 10.1016/j.nbt.2015.06.003. Epub 2015 Jul 8.
The effects of the suppression of UDP-glucose pyrophosphorylase (UGPase) on chrysolaminaran biosynthesis and carbon allocation were investigated in Phaeodactylum tricornutum. The 69% decrease in UGPase activity was accompanied by a 4.89 fold reduction in Ugp transcript abundance. Inactivation of UGP
PMID 26162893

Functional analysis of differentially expressed proteins in Chinese bayberry (Myrica rubra Sieb. et Zucc.) fruits during ripening.

Chen YY1, Zhang ZH2, Zhong CY3, Song XM3, Lin QH2, Huang CM3, Huang RH3, Chen W4.
Food chemistry.Food Chem.2016 Jan 1;190:763-70. doi: 10.1016/j.foodchem.2015.06.023. Epub 2015 Jun 10.
This study developed a proteome reference map of Myrica rubra fruits at the green, pink and red stages during ripening using two-dimensional gel electrophoresis (2-DE). Forty-six differentially expressed proteins were detected in the gel, of which 43 were successfully identified by matrix-assisted l
PMID 26213036

Gel-free/label-free proteomic analysis of root tip of soybean over time under flooding and drought stresses.

Wang X1, Oh M2, Sakata K3, Komatsu S4.
Journal of proteomics.J Proteomics.2016 Jan 1;130:42-55. doi: 10.1016/j.jprot.2015.09.007. Epub 2015 Sep 12.
Growth in the early stage of soybean is markedly inhibited under flooding and drought stresses. To explore the responsive mechanisms of soybean, temporal protein profiles of root tip under flooding and drought stresses were analyzed using gel-free/label-free proteomic technique. Root tip was analyze
PMID 26376099

Japanese Journal

Expression and Function of the P2y14 Receptor in Murine Peritoneal Macrophages

Kudo Fujimi,Nishiguchi Naoki,Ito Kyoko,Nakano Manabu,Ito Koichi
弘前医学 63(2-4), 96-104, 2012-11-30
… The P2Y14 receptor is activated by UDP-glucose （UDPG）, which is a well-known glycosyl donor that participates in the biosynthesis of carbohydrates, and is widely expressed in immune cells. …
NAID 120004994677

マウス腹腔マクロファージにおけるP2Y14受容体の発現と機能

工藤藤美,西口直樹,伊藤京子 [他]
弘前医学 63(2-4), 96-104, 2012-00-00
NAID 40019512718

Related Pictures

Biochemie und Pathobiochemie: UDP-Glucose Glycogen synthesis and degradation UDP glucose – Synthesis of the carrier UDP -glucose is formed from glucose-1 UDP-glucose is an intermediate in the UDP-glucose (UDP-Glc) in cellular pathways File:UDP-Glucose.svg - Wikipedia, the free

★リンクテーブル★

リンク元	「グルコース1-リン酸」「ウリジン二リン酸グルコース」「グリコーゲンシンターゼ」「UDPグルコースピロホスホリラーゼ」
拡張検索	「UDP-glucose pyrophosphorylase」
関連記事	「UDP」「U」

「グルコース1-リン酸」

Uridine diphosphate glucose
	IUPAC name [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
	Other names UDP-glucose
Identifiers
CAS number	133-89-1
PubChem	8629
ChemSpider	8308
MeSH	Uridine+Diphosphate+Glucose
ChEBI	CHEBI:52249
ChEMBL	CHEMBL375951
IUPHAR ligand	1783
Jmol-3D images	Image 1
	SMILES O=P(O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)CO)(O)OP(=O)(O)OC[C@H]3O[C@@H](N2/C=C\C(=O)NC2=O)[C@H](O)[C@@H]3O ;
	InChI InChI=1S/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1 ; Key: HSCJRCZFDFQWRP-JZMIEXBBSA-N InChI=1/C15H24N2O17P2/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25)/t5-,6-,8-,9-,10+,11-,12-,13-,14-/m1/s1; Key: HSCJRCZFDFQWRP-JZMIEXBBBU ;
Properties
Molecular formula	C15H24N2O17P2
Molar mass	566.302 g/mol
	(verify) (what is: /?); Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
	Infobox references