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spherical Gram-positive bacteria occurring in pairs or chains; cause e.g. scarlet fever and tonsillitis (同)streptococci, strep

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/02 03:55:46」(JST)

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Streptococcus sanguinis, formerly known as Streptococcus sanguis, is a Gram-positive facultative aerobic coccus species of bacteria and a member of the Viridans Streptococcus group. S. sanguinis is a normal inhabitant of the healthy human mouth where it is particularly found in dental plaque, where it modifies the environment to make it less hospitable for other strains of Streptococcus that cause cavities, such as Streptococcus mutans.

Pathogenicity

S. sanguinis may gain entrance to the bloodstream when opportunity presents (dental cleanings and surgeries) and colonize the heart valves, particularly the mitral and aortic valves, where it is the most common cause of subacute bacterial endocarditis. For this reason, oral surgeons often prescribe a short course of antibiotics to be taken a few days before to a few days after oral surgery. Once an infection has occurred, treatment is much more complicated and generally involves the administration of several weeks of penicillin and aminoglycoside antibiotics.

Genomics

The complete genomic sequence of S. sanguinis was determined in 2007 by laboratories at Virginia Commonwealth University.^[1]

References

^ Xu, Ping; Alves JM, Kitten T, Brown A, Chen Z, Ozaki LS, Manque P, Ge X, Serrano MG, Puiu D, Hendricks S, Wang Y, Chaplin MD, Akan D, Paik S, Peterson DL, Macrina FL, Buck GA (Apr 2007). "Genome of the opportunistic pathogen Streptococcus sanguinis". J Bacteriol 189 (8): 3166–75. doi:10.1128/JB.01808-06. PMID 17277061. Cite uses deprecated parameters (help)

External links

http://www.sanguinis.mic.vcu.edu/ S. sanguinis sequencing project

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UpToDate Contents

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1. 歯性感染症の疫学、病因、および臨床症状 epidemiology pathogenesis and clinical manifestations of odontogenic infections
2. 小児における滲出液を伴う中耳炎（滲出性中耳炎） otitis media with effusion serous otitis media in children
3. ベーチェット病の病因 pathogenesis of behcets disease

English Journal

Systematic Study Of Gene Functions For Chain Length In Streptococcus sanguinis.

Evans K, Stone V, Chen L, Ge X, Xu P.SourceVirginia Commonwealth University.
Microbiology (Reading, England).Microbiology.2013 Dec 2. doi: 10.1099/mic.0.071688-0. [Epub ahead of print]
Streptococcus sanguinis is a Gram-positive bacterium that is indigenous to the oral cavity. S. sanguinis, a primary colonizer of the oral cavity, serves as a tether for the attachment of other oral pathogens. The colonization of microbes on the tooth surface forms dental plaque, which can lead to th
PMID 24295823

Computer-assisted flapless implant placement reduces the incidence of surgery-related bacteremia.

Arısan V, Bölükbaşı N, Oksüz L.SourceDepartment of Oral Implantology, Faculty of Dentistry, Istanbul University, Capa, Istanbul, Turkey, varisan@istanbul.edu.tr.
Clinical oral investigations.Clin Oral Investig.2013 Dec;17(9):1985-93. doi: 10.1007/s00784-012-0886-y. Epub 2012 Dec 6.
OBJECTIVE: Bacteremia-the access of bacterium to the bloodstream-may yield life-threatening complications. The aim of this study was to compare the incidence, duration, and type of bacterium leading to bacteremia with relation to conventional and computer-assisted flapless implant surgery.MATERIAL A
PMID 23224042

Effects of azithromycin on intracellular cytokine responses and mucocutaneous manifestations in Behçet's disease.

Mumcu G, Inanç N, Ozdemir FT, Tulunay A, Ekşioğlu-Demiralp E, Ergun T, Direskeneli H.SourceDepartment of Health Informatics and Technologies, Faculty of Health Sciences, Marmara University, Istanbul, Turkey.
International journal of dermatology.Int J Dermatol.2013 Dec;52(12):1561-6. doi: 10.1111/ijd.12144. Epub 2013 Jul 24.
OBJECTIVE: The aim of this study was to investigate the effects of azithromycin on mucocutaneous manifestations and ex vivo intracellular cytokine responses in patients with Behçet's disease (BD).METHODS: Ten BD patients with active manifestations and nine healthy controls (HCs) were included in th
PMID 23879671

Japanese Journal

各種食品成分が口腔細菌種および誤嚥性肺炎起因菌種の増殖に及ぼす影響

大川勝正,結城茜,長澤正,杉山直人
日本食品科学工学会誌 : Nippon shokuhin kagaku kogaku kaishi = Journal of the Japanese Society for Food Science and Technology 58(3), 113-120, 2011-03-15
… sanguinis, S. …
NAID 10027868911

Bactericidal Activity in Filtrated Supernatant of Streptococcus Sanguinis against Multidrug-Resistant Pseudomonas Aeruginosa

WATANABE Kiwao,SENBA Masachika,ICHINOSE Akitoyo,YAMAMOTO Takeshi,ARIYOSHI Koya,MATSUMOTO Keizo
Tohoku journal of experimental medicine 219(2), 79-84, 2009-10-01
… Here we explored the bactericidal activity in the filtrated supernatant of Streptococcus (S.) sanguinis against Pseudomonas (P.) aeruginosa. … sanguinis is one of the α-hemolytic streptococci that commonly reside in the human oral cavity. … sanguinis, isolated from the sputum of a pulmonary-disease patient, was cultured for overnight. … sanguinis, and collapsed bacteria were detected with electron microscopy. …
NAID 10025534338

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リンク元	「Streptococcus oralis」

「Streptococcus oralis」

Streptococcus sanguinis
Scientific classification
Kingdom:	Bacteria
Phylum:	Firmicutes
Class:	Bacilli
Order:	Lactobacillales
Family:	Streptococcaceae
Genus:	Streptococcus
Species:	S. sanguinis
Binomial name
	Streptococcus sanguinis; White and Niven 1946