WordNet

(mechanics) the equal and opposite force that is produced when any force is applied to a body; "every action has an equal and opposite reaction"
a response that reveals a persons feelings or attitude; "he was pleased by the audiences reaction to his performance"; "John feared his mothers reaction when she saw the broken lamp"
a bodily process occurring due to the effect of some antecedent stimulus or agent; "a bad reaction to the medicine"; "his responses have slowed with age" (同)response
doing something in opposition to another way of doing it that you dont like; "his style of painting was a reaction against cubism"
an idea evoked by some experience; "his reaction to the news was to start planning what to do"
extreme conservatism in political or social matters; "the forces of reaction carried the election"
Austrian composer of waltzes (1804-1849) (同)Johann Strauss, Strauss the Elder
Austrian composer and son of Strauss the Elder; composed many famous waltzes and became known as the `waltz king (1825-1899) (同)Johann Strauss, Strauss the Younger
German composer of many operas; collaborated with librettist Hugo von Hoffmannsthal to produce several operas (1864-1949) (同)Richard Strauss

PrepTutorEJDIC

{名}(…に対する)『反応』《+『to』+『名』》 / 〈U〉(…に対する)(政治的・社会的な)『反動』,逆コース《+『against』+『名』》 / 〈U〉〈C〉化学反応,化学変化 / 〈U〉〈C〉(物理学で)反作用
シュトラウス / 『Johann』;オーストリアの作曲家;「ワルツの父」と呼ばれる) / 『Johann』~(1825‐1899;1の息子で作曲家;「ワルツの王」と呼ばれる) / 『Richard Strauss』(1864‐1949;ドイツの作曲家)

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1. 急性輸血反応が疑われる患者に対するアプローチ approach to the patient with a suspected acute transfusion reaction
2. 薬物アレルギー：分類および臨床的特徴 drug allergy classification and clinical features
3. 分子標的剤およびその他の生物製剤を用いた癌治療による皮膚合併症 cutaneous complications of molecularly targeted therapy and other biologic agents used for cancer therapy
4. Infusion reactions to systemic chemotherapy
5. 造影剤に対する即時型過敏反応：再発反応の予防 immediate hypersensitivity reactions to radiocontrast media prevention of recurrent reactions

The effect of exposure misclassification in spontaneous ADR reports on the time to detection of product-specific risks for biologicals: a simulation study.

Vermeer NS1,2, Ebbers HC1, Straus SM2,3, Leufkens HG1,2, Egberts TC1,4, De Bruin ML1,2.
Pharmacoepidemiology and drug safety.Pharmacoepidemiol Drug Saf.2016 Mar;25(3):297-306. doi: 10.1002/pds.3929. Epub 2015 Dec 16.
BACKGROUND AND OBJECTIVE: The availability of accurate product-specific exposure information is essential in the pharmacovigilance of biologicals, because differences in the safety profile may emerge between products containing the same active substance. In spontaneous adverse drug reaction (ADR) re
PMID 26676881

Drug-induced progressive multifocal leukoencephalopathy: Lessons learned from contrasting natalizumab and rituximab.

Vermeer NS1,2, Straus SM2,3, Mantel-Teeuwisse AK1, Hidalgo-Simon A4, Egberts AC1,5, Leufkens HG1,2, De Bruin ML1,2.
Clinical pharmacology and therapeutics.Clin Pharmacol Ther.2015 Nov;98(5):542-50. doi: 10.1002/cpt.207. Epub 2015 Sep 8.
Progressive multifocal leukoencephalopathy (PML) has been identified as a serious adverse drug reaction (ADR) of several immunomodulatory biologicals. In this study, we contrasted the reporting patterns of PML for two biologicals for which the risk was identified at different points in their lifecyc
PMID 26347128

Strategy in Regulatory Decision-Making for Management of Progressive Multifocal Leukoencephalopathy.

Segec A1, Keller-Stanislawski B2, Vermeer NS3,4, Macchiarulo C5, Straus SM4, Hidalgo-Simon A1, De Bruin ML3,4.
Clinical pharmacology and therapeutics.Clin Pharmacol Ther.2015 Nov;98(5):502-5. doi: 10.1002/cpt.199. Epub 2015 Sep 11.
Progressive multifocal leukoencephalopathy (PML) has been observed after the use of several medicines, including monoclonal antibodies. As these drugs play important roles in the therapeutic armamentarium, it is important to address the challenges that this severe adverse reaction poses to the safe
PMID 26250806