WordNet
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- (genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA
- a sound or television recording (e.g., from a broadcast to a tape recording)
- something written, especially copied from one medium to another, as a typewritten version of dictation (同)written text
PrepTutorEJDIC
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
- 〈U〉(…を)書き写す(書き直す)こと,(…の)転写,謄写《+of+名》 / 〈C〉写し(書き直し)[たもの] / 〈U〉〈C〉編曲[されたもの] / 〈U〉〈C〉(ラジオ・テレビの)録音(録画)
UpToDate Contents
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- 1. 常染色体優性多発性嚢胞腎の遺伝学および嚢胞成長のメカニズム genetics of autosomal dominant polycystic kidney disease and mechanisms of cyst growth
- 2. 成長ホルモンの生理学 physiology of growth hormone
- 3. 巨核球の生物学と血小板の産生 megakaryocyte biology and the production of platelets
- 4. 赤血球産生調節 regulation of erythropoiesis
- 5. 複合免疫不全 combined immunodeficiencies
English Journal
- Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.
- Villarino A1, Laurence A1, Robinson GW2, Bonelli M1, Dema B1, Afzali B1, Shih HY1, Sun HW1, Brooks SR1, Hennighausen L2, Kanno Y1, O'Shea JJ1.
- eLife.Elife.2016 Mar 21;5. pii: e08384. doi: 10.7554/eLife.08384. [Epub ahead of print]
- The transcription factor STAT5 is fundamental to the mammalian immune system. However, the relationship between its two paralogs, STAT5A and STAT5B, and the extent to which they are functionally distinct, remains uncertain. Using mouse models of paralog deficiency, we demonstrate that they are not e
- PMID 26999798
- Cytokine-induced megakaryocytic differentiation is regulated by genome-wide loss of a uSTAT transcriptional program.
- Park HJ1, Li J1, Hannah R1, Biddie S1, Leal-Cervantes AI1, Kirschner K1, Flores Santa Cruz D1, Sexl V2, Göttgens B3, Green AR4.
- The EMBO journal.EMBO J.2016 Mar 15;35(6):580-94. doi: 10.15252/embj.201592383. Epub 2015 Dec 23.
- Metazoan development is regulated by transcriptional networks, which must respond to extracellular cues including cytokines. The JAK/STAT pathway is a highly conserved regulatory module, activated by many cytokines, in which tyrosine-phosphorylated STATs (pSTATs) function as transcription factors. H
- PMID 26702099
- Prolactin inhibits a major tumor-suppressive function of wild type BRCA1.
- Chen KE1, Walker AM2.
- Cancer letters.Cancer Lett.2016 Mar 9. pii: S0304-3835(16)30143-4. doi: 10.1016/j.canlet.2016.03.007. [Epub ahead of print]
- Even though mutations in the tumor suppressor, BRCA1, markedly increase the risk of breast and ovarian cancer, most breast and ovarian cancers express wild type BRCA1. An important question is therefore how the tumor-suppressive function of normal BRCA1 is overcome during development of most cancers
- PMID 26970274
Japanese Journal
- Sex and circadian modulatory effects on rat liver as assessed by transcriptome analyses
- HIRAO Jun,NISHIMURA Masatoshi,ARAKAWA Shingo,NIINO Noriyo,MORI Kazuhiko,FURUKAWA Tadashi,SANBUISSHO Atsushi,MANABE Sunao,NISHIHARA Masugi,MORI Yuji
- Journal of toxicological sciences 36(1), 9-22, 2011-02-01
- … Furthermore, transcription factor targets modeling suggested that transcription factors SP1, hepatocyte nuclear factor 4-alpha (HNF4-alpha), and signal transducer and activator of transcription 5b (STAT5b) serve as core nodes in the regulatory networks. …
- NAID 10027420214
- JAK2変異体のシグナル伝達解析による真性赤血球増加症発症機構の解明
- 多胡(船越) めぐみ
- YAKUGAKU ZASSHI 131(8), 1183-1187, 2011
- … To clarify the signaling pathway of JAK2 V617F mutant, we investigated the functional role of downstream transcription factor STAT5 in its induced cellular transformation and tumorigenesis in nude mice. … Interestingly, JAK2 V617F mutant failed to exhibit transforming activity when STAT5 activation was inhibited utilizing EpoR mutant (HM). … Furthermore, the expression of constitutively active STAT5 mutant (1*6) exhibited transforming activity. …
- NAID 130001075906
Related Links
- Definition: A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE ...
- STAT5 Transcription Factor: A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN ...
Related Pictures
★リンクテーブル★
| リンク元 | 「STAT5転写因子」 |
| 関連記事 | 「fact」「factor」「transcription factor」「STA」「STAT」 |
「STAT5転写因子」
「fact」
- n.
「factor」
- n.