SLC25A5

English Journal

Proteomic analysis for the impact of hypercholesterolemia on expressions of hepatic drug transporters and metabolizing enzymes.

Liu Y1, Pu QH1, Wu MJ1, Yu C1.
Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.2016 Oct;46(10):940-7. doi: 10.3109/00498254.2016.1144228. Epub 2016 Feb 18.
1. Our objective is to investigate the alterations of hepatic drug transporters and metabolizing enzymes in hypercholesterolemia. Male Sprague-Dawley rats were fed high-cholesterol chows for 8 weeks to induce hypercholesterolemia. Protein levels of hepatic drug transporters and metabolizing enzymes
PMID 26887802

Mitochondrial ATP transporter Ant2 depletion impairs erythropoiesis and B lymphopoiesis.

Cho J1, Seo J2, Lim CH1, Yang L1, Shiratsuchi T3, Lee MH4, Chowdhury RR5, Kasahara H5, Kim JS4, Oh SP6, Lee YJ2, Terada N1.
Cell death and differentiation.Cell Death Differ.2015 Sep;22(9):1437-50. doi: 10.1038/cdd.2014.230. Epub 2015 Jan 23.
Adenine nucleotide translocases (ANTs) transport ADP and ATP through mitochondrial inner membrane, thus playing an essential role for energy metabolism of eukaryotic cells. Mice have three ANT paralogs, Ant1 (Slc25a4), Ant2 (Slc25a5) and Ant4 (Slc25a31), which are expressed in a tissue-dependent man
PMID 25613378

Adenine nucleotide translocase 4 is expressed within embryonic ovaries and dispensable during oogenesis.

Lim CH1, Brower JV2, Resnick JL3, Oh SP4, Terada N5.
Reproductive sciences (Thousand Oaks, Calif.).Reprod Sci.2015 Feb;22(2):250-7. doi: 10.1177/1933719114542026. Epub 2014 Jul 16.
Adenine nucleotide translocase (Ant) facilitates the exchange of adenosine triphosphate across the mitochondrial inner membrane and plays a critical role for bioenergetics in eukaryotes. Mice have 3 Ant paralogs, Ant1 (Slc25a4), Ant2 (Slc25a5), and Ant4 (Slc25a31), which are expressed in a tissue-de
PMID 25031318