SH3 domain

出典: meddic


SH2 domainSrc homology domain

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/27 20:39:07」(JST)

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  • Isoform-specific roles of the GTPase activating protein Nadrin in cytoskeletal reorganization of platelets.
  • Beck S, Fotinos A, Lang F, Gawaz M, Elvers M.SourceDepartment of Cardiology and Cardiovascular Medicine, University Clinic of Tübingen, Germany.
  • Cellular signalling.Cell Signal.2013 Jan;25(1):236-46. doi: 10.1016/j.cellsig.2012.09.005. Epub 2012 Sep 10.
  • Cytoskeletal reorganization of activated platelets plays a crucial role in hemostasis and thrombosis and implies activation of Rho GTPases. Rho GTPases are important regulators of cytoskeletal dynamics and function as molecular switches that cycle between an inactive and an active state. They are re
  • PMID 22975681
  • Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans.
  • McShea MA, Schmidt KL, Dubuke ML, Baldiga CE, Sullender ME, Reis AL, Zhang S, O'Toole SM, Jeffers MC, Warden RM, Kenney AH, Gosselin J, Kuhlwein M, Hashmi SK, Stringham EG, Ryder EF.SourceDepartment of Biology and Biotechnology, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA 01609, USA. Electronic address:
  • Developmental biology.Dev Biol.2013 Jan 1;373(1):1-13. doi: 10.1016/j.ydbio.2012.09.017. Epub 2012 Sep 27.
  • Directed cell migration and process outgrowth are vital to proper development of many metazoan tissues. These processes are dependent on reorganization of the actin cytoskeleton in response to external guidance cues. During development of the nervous system, the MIG-10/RIAM/Lamellipodin (MRL) signal
  • PMID 23022657
  • Characterization of the Functional Domains of the SloR Metalloregulatory Protein in Streptococcus mutans.
  • Haswell JR, Pruitt BW, Cornacchione LP, Coe CL, Smith EG, Spatafora GA.SourceMiddlebury College, Department of Biology, Middlebury, Vermont, USA.
  • Journal of bacteriology.J Bacteriol.2013 Jan;195(1):126-34. doi: 10.1128/JB.01648-12. Epub 2012 Oct 26.
  • Streptococcus mutans is a commensal member of the healthy plaque biofilm and the primary causative agent of dental caries. The present study is an investigation of SloR, a 25-kDa metalloregulatory protein that modulates genes responsible for S. mutans-induced cariogenesis. Previous studies of SloR h
  • PMID 23104811


  • 1PT157 Structural properties and folding process of hNck2 SH3 domain(The 50th Annual Meeting of the Biophysical Society of Japan)
  • Matsumura Yoshitaka,Shinjo Masaji,Matsui Tsutomu,Ichimura Kaoru,Song Jianxing,Kihara Hiroshi
  • 生物物理 52(SUPPLEMENT_1), S95, 2012-08-15
  • NAID 110009584996
  • 1PT115 Structural analysis of hNck2 SH3 domain at various pH : non-native α-helix-rich monomer and native dimer(The 50th Annual Meeting of the Biophysical Society of Japan)
  • Shinjio Masaji,Matsumura Yoshitaka,Ichimura Kaoru,Song Jianxing,Kihara Hiroshi
  • 生物物理 52(SUPPLEMENT_1), S88, 2012-08-15
  • NAID 110009584954
  • Genome-wide Investigation of the Rab Binding Activity of RUN Domains : Development of a Novel Tool that Specifically Traps GTP-Rab35
  • Fukuda Mitsunori,Kobayashi Hotaka,Ishibashi Koutaro [他]
  • Cell Structure and Function 36(1・2), 155-170, 2011-12-00
  • NAID 40019163999


米国CST社の日本法人CSTジャパン株式会社【公式サイト】プロリンリッチ配列の結合: SH3 ドメイン(領域)ページ。高品質の研究用試薬、米国本社の開発研究者による技術的サポートをご提供しております。
〈はじめに〉 SH3ドメインは、タンパク質のプロリンに富む領域と特異的に結合して、タンパク質-タンパク質間の相互作用を制御する機能ドメインであり、細胞内シグナル伝達に関与するタンパク質に広く見出されている。



リンク元SH2 domain」「Src相同性領域3」「Src homology domain」「SH3領域
拡張検索SH3 domains

SH2 domain」



SH3 domainSrc homology domain



SH3 domain

Src homology domain」


SH2 domainSH3 domain



SH3 domain

SH3 domains」


Src homology 3
Src homology 3



  • n.

WordNet   license wordnet

「territory over which rule or control is exercised; "his domain extended into Europe"; "he made it the law of the land"」
demesne, land

WordNet   license wordnet

「(mathematics) the set of values of the independent variable for which a function is defined」
domain of a function

PrepTutorEJDIC   license prepejdic

「(国の)領地,領土;(個人の)所有地 / (関心・活動などの)範囲,分野 / (個人・一族の)所有地 / (数学で)変域(関数の独立変数がとる値の集合)」



WordNet   license wordnet

「the 19th letter of the Roman alphabet」

PrepTutorEJDIC   license prepejdic

「sulfurの化学記号 / {略}South[ern]」





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