S-nitroso-N-acetylpenicillamine

S-ニトロソ-N-アセチルペニシラミン

WordNet

1. the 14th letter of the Roman alphabet (同)n
2. the 19th letter of the Roman alphabet (同)s

PrepTutorEJDIC

1. nitrogenの化学記号
2. sulfurの化学記号 / {略}South[ern]
3. neodymiumの化学記号

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/03 11:11:40」(JST)

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S-Nitroso-N-acetylpenicillamine

Names
IUPAC name S-Nitroso-N-acetylpenicillamine
Other names N-Acetyl-3-(nitrosothio)-DL-valine S-Nitroso-N-acetylpenicillamine
Identifiers
CAS Number	67776-06-1 N
Abbreviations	SNAP
ChEBI	CHEBI:77702 N
ChEMBL	ChEMBL73188 Y
ChemSpider	5036251 Y
InChI InChI=1S/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)/t5-/m0/s1 Y Key: ZIIQCSMRQKCOCT-YFKPBYRVSA-N Y InChI=1/C7H12N2O4S/c1-4(10)8-5(6(11)12)7(2,3)14-9-13/h5H,1-3H3,(H,8,10)(H,11,12)/t5-/m0/s1 Key: ZIIQCSMRQKCOCT-YFKPBYRVBE
Jmol interactive 3D	Image
PubChem	6603945
SMILES O=C(N[C@@H](C(=O)O)C(SN=O)(C)C)C
Properties
Chemical formula	C7H12N2O4S
Molar mass	220.25 g/mol
Hazards
R-phrases	R36/37/38
S-phrases	S26 S36
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

S-Nitroso-N-acetylpenicillamine (SNAP) is the chemical compound with the formula ONSC(CH₃)₂CH(NHAc)CO₂H. SNAP is an S-nitrosothiol and is used as a model for the general class of S-nitrosothiols which have received much attention in biochemistry because nitric oxide and some organic nitroso derivatives serve as signaling molecules in living systems, especially related to vasodilation. SNAP is derived from the amino acid penicillamine. S-Nitrosoglutathione is a related agent.

References

UpToDate Contents

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English Journal

• The effect of protein kinase C activator and nitric oxide donor on oocyte activation and cortical granule exocytosis in porcine eggs.

• Tůmová L, Romar R, Petr J, Sedmíková M.SourceDepartment of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences in Prague, 165 21 Prague 6-Suchdol, Czech Republic. tumoval@af.czu.cz
• Animal : an international journal of animal bioscience.Animal.2013 Feb;7(2):279-86. doi: 10.1017/S1751731112001127. Epub 2012 Jun 8.
• Nitric oxide (NO) and protein kinase C (PKC) are involved in the activation of mammalian oocytes, although their role in the exit from the metaphase II stage and cortical granule (CG) exocytosis is still not fully understood. The aim of this study was to verify whether the NO-donor together with spe
• PMID 23031262

• Proteome changes associated with Leishmania donovani promastigote adaptation to oxidative and nitrosative stresses.

• Sardar AH, Kumar S, Kumar A, Purkait B, Das S, Sen A, Kumar M, Sinha KK, Singh D, Equbal A, Ali V, Das P.SourceDivision of Molecular Biology, Rajendra Memorial Research Institute of Medical Sciences, Agamkuan, Patna-800007, Bihar, India.
• Journal of proteomics.J Proteomics.2013 Jan 30. pii: S1874-3919(13)00039-0. doi: 10.1016/j.jprot.2013.01.011. [Epub ahead of print]
• Phagocytic cells produce reactive oxygen and nitrogen species (ROS & RNS) as the most common arsenal to kill intracellular pathogens. Leishmania, an obligate intracellular pathogen also confronts this antimicrobial assault during the early phase of infection but nevertheless is able to survive t
• PMID 23376486

• Cutting edge: nitric oxide inhibits the NLRP3 inflammasome.

• Hernandez-Cuellar E, Tsuchiya K, Hara H, Fang R, Sakai S, Kawamura I, Akira S, Mitsuyama M.SourceDepartment of Microbiology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.
• Journal of immunology (Baltimore, Md. : 1950).J Immunol.2012 Dec 1;189(11):5113-7. doi: 10.4049/jimmunol.1202479. Epub 2012 Oct 24.
• Although the NLRP3 inflammasome plays a pivotal role in host defense, its uncontrolled activation is associated with inflammatory disorders, suggesting that regulation of the inflammasome is important to prevent detrimental effects. Type I IFNs and long-term LPS stimulation were shown to negatively
• PMID 23100513

Japanese Journal

• Glycyrrhetinic Acid Reverses the Lipopolysaccharide-Induced Hypocontractility to Noradrenaline in Rat Aorta: Implications to Septic Shock

• Journal of Pharmacological Sciences 125(4), 422-425, 2014
• NAID 130004677793

• Effect of Overexpression of the Brain-Specific Na⁺/Ca²⁺ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells

• Journal of pharmacological sciences 121(4), 351-354, 2013-04-20
• NAID 10031171147

• Nitric Oxide Stimulates Vascular Endothelial Growth Factor Production in Cardiomyocytes Involved in Angiogenesis

• The journal of physiological sciences : JPS 56(1), 95-101, 2006-02-01
• NAID 10019252887

Related Links

• (±)-S-Nitroso-N-acetylpenicillamine | CAS 79032-48-7 ...

(±)-S-Nitroso-N-acetylpenicillamine (SNAP) is a NO donor and cysteine protease inhibitor. The unique NO releasing properties of SNAP make it an ideal agent for studying the pharmacological and physiological actions of NO since it ...

• (±)-S-Nitroso-N-acetylpenicillamine | CAS 79032-48-7 | Santa ...

Buy this product (CAS 79032-48-7), a cysteine protease inhibitor and spontaneous NO donor in physiological conditions, from Santa Cruz. Purity: ≥98% ... Synonym: S-Nitroso-N-acetyl-DL-penicillamine; SNAP; N-(acetyloxy)-3 ...

Related Pictures

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★リンクテーブル★

リンク元	「S-ニトロソ-N-アセチルペニシラミン」
関連記事	「n」「N」「S」「Nd」

「S-ニトロソ-N-アセチルペニシラミン」

　　[★]

英

S-nitroso-N-acetylpenicillamine

「n」

　　[★]

• n.

• 例数

関

number of experiment、sample size

• pの前の[n]はmと記載する。synptom→symptom

「N」

　　[★]

• アスパラギン asparagine
• 窒素(原子、分子)

　 　

「S」

　　[★]

• セリン serine
• 胸骨上縁

　 　

「Nd」

　　[★] ネオジム neodymium