Rothia dentocariosa

ロチア・デントカリオーサ

WordNet

1. United States writer whose novels portray middle-class Jewish life (born in 1933) (同)Philip Roth, Philip Milton Roth

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/03/18 18:20:42」(JST)

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Rothia dentocariosa
Scientific classification
Kingdom:	Bacteria
Genus:	Rothia
Species:	dentocariosa

Rothia dentocariosa is a species of gram-positive, round- to rod-shaped bacteria that is part of the normal community of microbes residing in the mouth and respiratory tract.

First isolated from dental caries, Rothia dentocariosa is largely benign, but does very rarely cause disease. The most common Rothia infection is endocarditis, typically in people with underlying heart valve disorders. Literature case reports show other tissues that are rarely infected include the peritoneum, tonsils, lung, cornea, inner layers of the eye (Endophthalmitis) and brain and intercranial tissues. It has been implicated in periodontal disease, and one hypothesis is that Rothia periodontal disease, or dental procedures in turn, may be first steps in the infection of other tissues. One case reports on a fatal Rothia dentocariosa infection of a fetus in utero. Another reports the bacterium was responsible for septic arthritis in the knee of a person treated with etanercept for rheumatoid arthritis. Like other Rothia infections reported in the literature, once the cause of infection was identified, this responded fully to treatment with antibiotics. Rothia infections may be treated with penicillins, erythromycin, cefazolin, rifampin, aminoglycoside, tetracycline, chloramphenicol, and trimethoprim-sulfamethoxazole.

Variable or pleomorphic in shape and similar to Actinomyces and Nocardia, Rothia was only defined as a genus in 1967. Rothia dentocariosa, like several other species of oral bacteria, is able to reduce nitrate to nitrite, and one study found it in 3% of isolates of nitrate-reducing bacteria from the mouth.

References

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• 1. ノカルジア症の微生物学、疫学、および病因 microbiology epidemiology and pathogenesis of nocardiosis
• 2. 感染性（真菌）大動脈瘤の概要 overview of infected mycotic arterial aneurysm

English Journal

• A novel selective medium for the isolation and distribution of Rothia dentocariosa in oral cavities.

• Uchibori S, Tsudukibashi O, Goto H, Kobayashi T, Aida M.SourceNihon University Graduate School of Dentistry at Matsudo, Crown Bridge Prosthodontics, Chiba 271-8587, Japan. Electronic address: masa09006@g.nihon-u.ac.jp.
• Journal of microbiological methods.J Microbiol Methods.2012 Oct;91(1):205-7. doi: 10.1016/j.mimet.2012.07.004. Epub 2012 Jul 11.
• Rothia dentocariosa is an indigenous microbial flora of dental plaque. To examine the bacterium population in oral cavities, a novel selective medium, designated RDSM, was developed for the isolation of R. dentocariosa. RDSM was prepared by adding 0.5μg/ml of lincomycin, 10μg/ml of colistin, and 4
• PMID 22796060

• Impact of periodontal therapy on the subgingival microbiota of severe periodontitis: comparison between good responders and individuals with refractory periodontitis using the human oral microbe identification microarray.

• Colombo AP, Bennet S, Cotton SL, Goodson JM, Kent R, Haffajee AD, Socransky SS, Hasturk H, Van Dyke TE, Dewhirst FE, Paster BJ.SourceDepartment of Medical Microbiology, Institute of Microbiology of Federal University of Rio de Janeiro, Brazil. apcolombo@micro.ufrj.br
• Journal of periodontology.J Periodontol.2012 Oct;83(10):1279-87. Epub 2012 Feb 10.
• BACKGROUND: This study compares the changes to the subgingival microbiota of individuals with "refractory" periodontitis (RP) or treatable periodontitis (good responders [GR]) before and after periodontal therapy by using the Human Oral Microbe Identification Microarray (HOMIM) analysis.METHODS: Ind
• PMID 22324467

Japanese Journal

• New Primer Design for Identification of Oral rothia, Including R. aeria, Using Multiplex PCR

• Tsuzukibashi Osamu,Uchibori Satoshi,Shinozaki-Kuwahara Noriko,Saito Masanori,Kobayashi Taira,Fukumoto Masahiko
• International Journal of Oral-Medical Sciences 12(2), 85-89, 2013
• … We previously reported a primer design for the identification of oral Rothia dentocariosa and Rothia mucilaginosa, using multiplex polymerase chain reaction（PCR）. … There is only one report of Rothia aeria, which is capable of causing serious systemic infections, being detected in the mouths of healthy individuals. …
• NAID 130003386570

• A Novel Selective Medium for the Isolation of Rothia aeria in Oral Cavities

• Nebuka Kenichi,Tsuzukibashi Osamu
• International Journal of Oral-Medical Sciences 12(2), 79-84, 2013
• … Among the genus Rothia, Rothia dentocariosa and Rothia mucilaginosa are found in oral cavity and pharynx of humans. … Furthermore, there is only one report that Rothia aeria,which is capable of causing serious systemic infections, has been also detected in the mouths of healthy individuals. … dentocariosa, R. …
• NAID 130003386569

• Localization of the Genus Rothia in the Oral Cavity

• Uchibori Satoshi,Tsuzukibashi Osamu,Kobayashi Taira,Aida Masahiro
• International Journal of Oral-Medical Sciences 11(3), 207-210, 2013
• … Among the genus Rothia, R. … dentocariosa and R. … The clinical efficacy of the genus Rothia was evaluated from samples of oral cavities, such as pit and fissure plaque, buccal surface plaque, the buccal membrane surface, the dorsum of tongue, gingival crevicular fluid (GCF), and the mucosal surface of denture base using these selective media. … dentocariosa and R. … Therefore, both Rothia species are common members of oral cavity. …
• NAID 130003375175

Related Links

• 化粧品からRothia dentocariosa - 臨床微生物迅速診断研究会

化粧品からRothia dentocariosa 【質問】 はじめまして。化粧品の品質管理をしています。 先日化粧品より検出した菌を市販の同定キット (BBL CRYSTAL GP) にて同定したところ, Rothia dentocariosaという同定結果がでました。聞いた ...

• Rothia mucilaginosa Stomatococcus mucilaginosus 1

13) Lee, A. B., P. Harker-Murray, P. Ferrieri, et al. 2008. Bacterial meningitis from Rothia muci-laginosa in patients with malignancy or under-going hematopoietic stem cell transplantation. Pediatr. Blood Cancer 50: 673 676. 14 ...

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Rothia dentocariosa