WordNet

mark with lines; "sorrow had lined his face"
a length (straight or curved) without breadth or thickness; the trace of a moving point
a single frequency (or very narrow band) of radiation in a spectrum
reinforce with fabric; "lined books are more enduring"
a particular kind of product or merchandise; "a nice line of shoes" (同)product line, line of products, line of merchandise, business line, line of business
the road consisting of railroad track and roadbed (同)railway line, rail line
a commercial organization serving as a common carrier
acting in conformity; "in line with"; "he got out of line"; "toe the line"
something (as a cord or rope) that is long and thin and flexible; "a washing line"
a conceptual separation or distinction; "there is a narrow line between sanity and insanity" (同)dividing_line, demarcation, contrast
a formation of people or things one behind another; "the line stretched clear around the corner"; "you must wait in a long line at the checkout counter"
a formation of people or things one beside another; "the line of soldiers advanced with their bayonets fixed"; "they were arrayed in line of battle"; "the cast stood in line for the curtain call"
a fortified position (especially one marking the most forward position of troops); "they attacked the enemys line"
a mark that is long relative to its width; "He drew a line on the chart"
a spatial location defined by a real or imaginary unidimensional extent
in games or sports; a mark indicating positions or bounds of the playing area
persuasive but insincere talk that is usually intended to deceive or impress; "`let me show you my etchings is a rather worn line"; "he has a smooth line but I didnt fall for it"; "that salesman must have practiced his fast line of talk"
text consisting of a row of words written across a page or computer screen; "the letter consisted of three short lines"; "there are six lines in every stanza"
be in line with; form a line along; "trees line the riverbank" (同)run along
cover the interior of; "line the gloves"; "line a chimney"
fill plentifully; "line ones pockets"
providing something with a surface of a different material (同)facing
a protective covering that protects an inside surface (同)liner
the act of attaching an inside lining (to a garment or curtain etc.)
having a lining or a liner; often used in combination; "a lined skirt"; "a silk-lined jacket"
(used especially of skin) marked by lines or seams; "their lined faces were immeasurably sad"; "a seamed face" (同)seamed
bordered by a line of things; "tree lined streets"
a member of a Buddhist people living in Myanmar and adjacent parts of Thailand
the Mon-Khmer language spoken by the Mon

PrepTutorEJDIC

『線』,筋,けい / (色・縫い目などの)『線』,しま;(顔・手などの)しわ(wrinkle) / (物・人の)『列』,行列(row) / 『綱』,糸,針金 / 電線,電話線,電信線 / (文章の)『行』;(詩の)『行』 / 《しばしばa~》《話》『短い手紙』(note) / 《複数形で》輪郭,外形(outline) / 境界線(boundary);限界,限度(limit) / (鉄道・バスなどの)路線;航路,空路 / 《複数形で》せりふ / 進路,道順(course);(考えなどの)筋道,方針 / 《しばしばone's~》(活動の)分野,方面;特意 / 家系,血統,血筋 / 在庫商品,仕入れ品 / 導管,パイプライン / 《しばしば複数形で》戦線,防御線 / …‘に'『線を引く』,筋(しま,しわ)をつける / …‘に'『沿って並ぶ;』(…を)…‘に'沿って並べる《+『名』+『with』+『名』》
(材料で)〈着物など〉‘に'裏を付ける《+『名』『with』+『名』》 / (…で)…‘を'満たす,(…を)…‘に'詰め込む《+『名』+『with』+『名』》
〈U〉(服などの)裏張り,裏塗り / 〈U〉裏地,裏材

UpToDate Contents

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1. 慢性リンパ球性白血病/小リンパ球性リンパ腫のリヒタートランスフォーメーションrichter transformation in chronic lymphocytic leukemia small lymphocytic lymphoma [show details]
… Richter transformation (RT; Richter syndrome) was first described in 1928 by Maurice Richter as the development of an aggressive large-cell lymphoma in the… for patients with DLBCL relapsed after two or more lines of systemic therapy.…
2. 成人における腹壁ヘルニアの概要overview of abdominal wall hernias in adults [show details]
… hernias are Richter hernias. When it perforates into the hernia sac, a Richter type hernia can also present in a delayed fashion as an enterocutaneous fistula. The diagnosis of a Richter hernia… belt," a transverse 6-cm-wide zone around the level of the arcuate line . The arcuate line is the caudalmost extent of the posterior rectus sheath.…
3. 慢性リンパ性白血病の治療による奏効の評価evaluating response to treatment of chronic lymphocytic leukemia [show details]
… in an analysis of data from three trials of first-line chemoimmunotherapy,… Richter transformation). Richter transformation is suspected in patients who develop rapidly…
4. 再発性または難治性の慢性リンパ性白血病の治療treatment of relapsed or refractory chronic lymphocytic leukemia [show details]
… the same indications used for first-line therapy are used at the time of relapse or progressive disease.… Transformation to a more aggressive histologic subtype (Richter transformation) should be suspected in patients with rapid progression of lymphadenopathy,…
5. 慢性リンパ性白血病の病態生理pathobiology of chronic lymphocytic leukemia [show details]
…minimum follow-up of 15 years, Richter transformation developed in 34 patients (7 percent) and PLL developed in 10 patients (2 percent). The incidence of Richter transformation and PLL was independent of initial …

English Journal

Fluid resuscitation in human sepsis: Time to rewrite history?

Byrne L1,2, Van Haren F3,4.
Annals of intensive care.Ann Intensive Care.2017 Dec;7(1):4. doi: 10.1186/s13613-016-0231-8. Epub 2017 Jan 3.
Fluid resuscitation continues to be recommended as the first-line resuscitative therapy for all patients with severe sepsis and septic shock. The current acceptance of the therapy is based in part on long history and familiarity with its use in the resuscitation of other forms of shock, as well as o
PMID 28050897

Priming increases the anti-tumor effect and therapeutic window of 177Lu-octreotate in nude mice bearing human small intestine neuroendocrine tumor GOT1.

Dalmo J1, Spetz J2, Montelius M2, Langen B2, Arvidsson Y3, Johansson H2, Parris TZ4, Helou K4, Wängberg B5, Nilsson O3, Ljungberg M2, Forssell-Aronsson E2.
EJNMMI research.EJNMMI Res.2017 Dec;7(1):6. doi: 10.1186/s13550-016-0247-y. Epub 2017 Jan 5.
BACKGROUND: 177Lu-[DOTA0, Tyr3]-octreotate (177Lu-octreotate) is used for treatment of patients with somatostatin receptor (SSTR) expressing neuroendocrine tumors. However, complete tumor remission is rarely seen, and optimization of treatment protocols is needed. In vitro studies have shown that ir
PMID 28097640

Synthesis and in vitro anti-proliferative activity of some novel isatins conjugated with quinazoline/phthalazine hydrazines against triple-negative breast cancer MDA-MB-231 cells as apoptosis-inducing agents.

Eldehna WM1, Almahli H1,2, Al-Ansary GH3, Ghabbour HA4, Aly MH5,6, Ismael OE7, Al-Dhfyan A8, Abdel-Aziz HA9.
Journal of enzyme inhibition and medicinal chemistry.J Enzyme Inhib Med Chem.2017 Dec;32(1):600-613. doi: 10.1080/14756366.2017.1279155.
Treatment of patients with triple-negative breast cancer (TNBC) is challenging due to the absence of well- defined molecular targets and the heterogeneity of such disease. In our endeavor to develop potent isatin-based anti-proliferative agents, we utilized the hybrid-pharmacophore approach to synth
PMID 28173708

「モンロー・リヒター線」

　　[★]

英: Monro-Richter line
同: リヒター-モンロー線 Richter-Monro線 Monro-Richterの線 Richter-Monro line, モンロー-リヒター線 Monro-Richter線、左臍棘線

[show details]

ja

リヒター-モンロー線 : 2 件
モンロー-リヒター線 : 23 件
Richter-Monro line : nothing
Monro-Richter line : 20 件

en

Richter-Monro line : 約 40 件
Monro-Richter line : 約 52 件

腹腔穿刺の目印。臍と左上前腸骨棘を結んだ線上で、この線の中央よりやや外側の点を穿刺する。

参考

シェーマ

http://www.37wiki.com/uploads/201008/1281666164IBIKJiPG.png

http://jpkc.fimmu.com/wkx-nfyy/waikexue/content/tpzy/pic/4-2/24.bmp

「LINE」

　　[★]

日: 長い散在反復配列、長散在型反復配列、長い散在性反復配列、ライン、広範囲散在反復配列
英: long interspersed nuclear element, long interspersed nucleotide element, long interspersed element, long interspersed repetitive elements, LINEs, long interspersed repeat sequences
関: レトロトランスポゾン

quoted from http://en.wikipedia.org/wiki/Long_interspersed_nucleotide_elements#LINEs

Long interspersed nuclear elements[8] are a group of genetic elements that are found in large numbers in eukaryotic genomes. They are transcribed (or are the evolutionary remains of what was once transcribed) to an RNA using an RNA polymerase II promoter that resides inside the LINE. LINEs code for the enzyme reverse transcriptase, and many LINEs also code for an endonuclease (e.g. RNase H). The reverse transcriptase has a higher specificity for the LINE RNA than other RNA, and makes a DNA copy of the RNA that can be integrated into the genome at a new site.

The 5' UTR contains the promoter sequence, while the 3' UTR contains a polyadenylation signal (AATAAA) and a poly-A tail.[10] Because LINEs move by copying themselves (instead of moving, like transposons do), they enlarge the genome. The human genome, for example, contains about 20,000-40,000 LINEs, which is roughly 21% of the genome.