Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/05/03 19:05:17」(JST)

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

Guzman E1, Taylor G2.
Molecular immunology.Mol Immunol.2015 Jul;66(1):48-56. doi: 10.1016/j.molimm.2014.12.004. Epub 2014 Dec 29.
Bovine respiratory syncytial virus (BRSV) is an important cause of respiratory disease in young calves. The virus is genetically and antigenically closely related to human (H)RSV, which is a major cause of respiratory disease in young infants. As a natural pathogen of calves, BRSV infection recapitu
PMID 25553595

The partial attenuation of Small Hydrophobic (SH) gene deleted RSV is associated with elevated IL-1β responses.

Russell RF1, McDonald JU1, Ivanova M1, Zhong Z1, Bukreyev A2, Tregoning JS3.
Journal of virology.J Virol.2015 Jun 17. pii: JVI.01070-15. [Epub ahead of print]
The small hydrophobic (SH) gene of respiratory syncytial virus (RSV), a major cause of infant hospitalisation, encodes a viroporin of unknown function. SH gene knockout virus (RSV ΔSH) is partially attenuated in vivo but not in vitro, suggesting that the SH protein may have an immunomodulatory role
PMID 26085154

Zinc binding activity of human metapneumovirus M2-1 protein is indispensable for viral replication and pathogenesis in vivo.

Cai H1, Zhang Y1, Ma Y1, Sun J1, Liang X1, Li J2.
Journal of virology.J Virol.2015 Jun;89(12):6391-405. doi: 10.1128/JVI.03488-14. Epub 2015 Apr 8.
Human metapneumovirus (hMPV) is a member of the Pneumovirinae subfamily in the Paramyxoviridae family that causes respiratory tract infections in humans. Unlike members of the Paramyxovirinae subfamily, the polymerase complex of pneumoviruses requires an additional cofactor, the M2-1 protein, which
PMID 25855728