POMC deficiency

同

pro-opiomelanocortin

PrepTutorEJDIC

1. 〈U〉〈C〉(…の)(量・額などの)不足,欠乏《+『of』(『in』)+『名』》 / 〈C〉不足分,不足量,不足額 / 〈C〉(精神・肉体などの)欠陥

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 成人における二次性および三次性副腎不全の原因 causes of secondary and tertiary adrenal insufficiency in adults
• 2. 成人における副腎不全の臨床症状 clinical manifestations of adrenal insufficiency in adults
• 3. 小児における中枢性副腎不全の原因および臨床症状 causes and clinical manifestations of central adrenal insufficiency in children
• 4. ACTH、CRH、および他の視床下部／下垂体ペプチドの測定 measurement of acth crh and other hypothalamic and pituitary peptides
• 5. コルチコトロピン-放出ホルモン（CRH）の生理学 physiology of corticotropin releasing hormone

English Journal

• Neuroendocrinology: New hormone treatment for obesity caused by POMC-deficiency.

• Low MJ1.
• Nature reviews. Endocrinology.Nat Rev Endocrinol.2016 Sep 23. doi: 10.1038/nrendo.2016.156. [Epub ahead of print]
• PMID 27658726

• Metabolic Precision Medicines: Curing POMC Deficiency.

• Müller TD1, Tschöp MH2, O'Rahilly S3.
• Cell metabolism.Cell Metab.2016 Aug 9;24(2):194-5. doi: 10.1016/j.cmet.2016.07.006. Epub 2016 Jul 21.
• Pro-opiomelanocortin deficiency is a rare cause of severe intractable obesity. Two patients have experienced dramatic weight loss in response to setmelanotide, a melanocortin-4 receptor activator. The drug has potential in broader populations, but caution is warranted as it may act at other melanoco
• PMID 27452145

• Melatonin Receptor 1-Deficiency Affects Feeding Dynamics and Pro-Opiomelanocortin Expression in the Arcuate Nucleus and Pituitary of Mice.

• Fischer C1, Mueller T, Pfeffer M, Wicht H, von Gall C, Korf HW.
• Neuroendocrinology.Neuroendocrinology.2016 Aug 5. [Epub ahead of print]
• BACKGROUND/METHODS: Melatonin, the neurohormone for darkness, mediates photoperiod dependent changes in physiology and behavior by targeting specific membrane bound receptors (MT1 and MT2). In the present study, we investigated the impact of MT1 receptor-deficiency on feeding behavior, locomotor act
• PMID 27490331

Japanese Journal

• Isolated adrenocorticotropic hormone deficiency presenting with psychomotor retardation

• Pediatrics international : official journal of the Japan Pediatric Society 49(4), 522-525, 2007-08-01
• NAID 10019814984

• Does Radiation Therapy for Brain Tumor Affect Pituitary Function, Resulting in Isolated ACTH Deficiency?

• Internal medicine 41(6), 417, 2002-06-01
• NAID 10008548276

Related Links

• Proopiomelanocortin deficiency - Genetics Home Reference

Proopiomelanocortin (POMC) deficiency causes severe obesity that begins at an early age. In addition to obesity, people with this condition have low levels of a hormone known as adrenocorticotropic hormone (ACTH) and ...

• POMC deficiency - RightDiagnosis.com - Right Diagnosis

POMC deficiency symptoms, causes, diagnosis, and treatment information for POMC deficiency (Obesity due to pro-opiomelanocortin Deficiency) with alternative diagnoses, full-text book chapters, misdiagnosis, research treatments ...

---

★リンクテーブル★

関連記事	「deficiency」「PO」「POM」「POMC」

「deficiency」

　　[★]

• n.

• 不足、欠乏、欠失、欠如、欠損、不十分。栄養不足、栄養素欠乏、欠乏症。(遺伝子)(染色体内の)遺伝子欠失
• 欠けているもの、不足している物。不足分。不完全なもの、欠点のあるもの

関

absence, agenesis, dearth, defect, defective, deficient, deficit, delete, deletion, deletional, depletion, deprivation, deprive, lack, miss, missing, morphological defect, paucity, scarce, scarcity, starve

　

「PO」

　　[★]

• ペルオキシダーゼ peroxidase
• 経口 per os, p.o.

「POM」

　　[★]

• 部分大網切除、部分大網切除術

「POMC」

　　[★] プロオピオメラノコルチン