PEG

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/05/29 15:12:25」(JST)

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英文文献

  • Vasoactive effects of stable aqueous suspensions of single walled carbon nanotubes in hamsters and mice.
  • Frame MD1, Dewar AM, Mullick Chowdhury S, Sitharaman B.Author information 1Department of Biomedical Engineering, Stony Brook University , Stony Brook, NY 11794 , USA.AbstractSingle-walled carbon nanotubes synthesized with iron (Fe-SWCNT) or gadolinium (Gd-SWCNT) show promise as high performance multimodal contrast and drug-delivery agents. Our purpose was to evaluate potential vasoactive effects of SWCNT. Stable aqueous solutions of Fe-SWCNTs or Gd-SWCNTs were made using the biocompatible amphiphilic polymer N-(carbonyl-methoxypolyethyleneglycol 2000)-1,2-distearoylsn-glycero-3- phosphoethanolamine (PEG-DSPE). Both aggregated and non-aggregated (sonicated) formulations were tested. The initial vasoactivity of the formulations and their potential for inducing pro-inflammatory endothelial dysfunction were investigated in the hamster cheek pouch and murine cremaster muscle intravital microscopy models. These models provide an assay to test several formulations/dosages in a paired fashion. Abluminal exposure to small arterioles exposes both endothelial and vascular smooth muscle cells. Using abluminal exposures of dosages that would approximate the first pass of an i.v. bolus injection, both Fe-SWCNTs and Gd-SWCNTs were immediately vasoactive. Aggregated formulations induced dilation and non-aggregated formulations induced constriction in both hamsters and mice. Endothelial dysfunction was evident after exposure to either aggregated or non-aggregated forms. General loss of dilator capability was seen after exposure to non-aggregated but not aggregated forms. Thus concentrations mimicking bolus dosing of PEG-DSPE coated SWCNT induce both acute and chronic vascular responses.
  • Nanotoxicology.Nanotoxicology.2014 Dec;8(8):867-75. doi: 10.3109/17435390.2013.837209. Epub 2013 Sep 30.
  • Single-walled carbon nanotubes synthesized with iron (Fe-SWCNT) or gadolinium (Gd-SWCNT) show promise as high performance multimodal contrast and drug-delivery agents. Our purpose was to evaluate potential vasoactive effects of SWCNT. Stable aqueous solutions of Fe-SWCNTs or Gd-SWCNTs were made usin
  • PMID 23992463
  • Nontoxic impact of PEG-coated gold nanospheres on functional pulmonary surfactant-secreting alveolar type II cells.
  • Bouzas V1, Haller T, Hobi N, Felder E, Pastoriza-Santos I, Pérez-Gil J.Author information 1Departamento de Bioquímica y Biología Molecular I, Facultad de Biología, Universidad Complutense , Madrid , Spain.AbstractThe outstanding properties of gold nanoparticles (NPs) make them very attractive for biomedical applications. In particular, the inhalation route has gained considerable interest as an innovative strategy for diagnosis and treatment of pulmonary diseases. It is, therefore, important to scrutinise the potentially deleterious or side effects of NPs on lung epithelium. The present study investigates, for the first time, the impact of polyethylene glycol (PEG)-coated NPs on freshly purified primary cultures of rat alveolar type II (ATII) cells. These cells play a central role in the respiratory function of the lungs. They are responsible for synthesizing and secreting pulmonary surfactant (PS), which is required to stabilise the respiratory surface during breathing dynamics. Cytotoxicity and cellular uptake of NPs was evaluated by analysing morphology, viability and exocytotic activity of ATII cells (PS secretion). The impact of ATII cells' exposure to NPs was studied in a wide range of gold concentration with particles sizes of 15 and 100 nm. The results show that PEG-coated NPs are very modestly internalised by ATII cells and it neither leads to detectable morphological changes nor to decreased cell viability nor to alterations in basic functional parameters such as PS secretion, even on exposure to high gold concentration (~0.2 mM) during relatively long periods of time (24-48 h).
  • Nanotoxicology.Nanotoxicology.2014 Dec;8(8):813-23. doi: 10.3109/17435390.2013.829878. Epub 2013 Aug 27.
  • The outstanding properties of gold nanoparticles (NPs) make them very attractive for biomedical applications. In particular, the inhalation route has gained considerable interest as an innovative strategy for diagnosis and treatment of pulmonary diseases. It is, therefore, important to scrutinise th
  • PMID 23914786
  • Controlled porosity osmotic pump system for the delivery of diclofenac sodium: in-vitro and in-vivo evaluation.
  • Emara LH1, Taha NF, El-Ashmawy AA, Raslan HM, Mursi NM.Author information 1Industrial Pharmacy Laboratory , Medicinal and Pharmaceutical Chemistry Department and.AbstractThe objective of this study was to develop controlled porosity osmotic pump (CPOP) tablets of diclofenac sodium (DS). The influence of different cores (polymers and osmogens) and coats (thickness and porosigen content) on DS release were studied. Results revealed that decreasing HPMC viscosity grade from 4000cp (K4M) to 15cp (E15) increased DS release. While increasing the tablet coat thickness decreased DS release. The presence of osmogen increased DS release in the following rank: mannitol > lactose > avicel. There was a direct relationship between increasing PEG-400 in the coating solution and the amount of drug released in all formulations studied, except in one condition. A comparative bioavailability study using a selected CPOP formulation (T) versus the innovator product (R) revealed that CPOP tablet maintained a less fluctuated DS plasma concentration for up to 24 h with a detected mean Cmax of 836.8 ± 142.4 and 445.0 ± 81.0 ng/mL for R and T, respectively. There were no statistically significant differences between R and T, concerning AUC0-24 and AUC0-∞. Moreover, the appearance of the multi-peak phenomenon, which is frequently observed with DS absorption, was found in only 25% of volunteers in case of T versus 75% in case of R.
  • Pharmaceutical development and technology.Pharm Dev Technol.2014 Sep;19(6):681-91. doi: 10.3109/10837450.2013.823990.
  • The objective of this study was to develop controlled porosity osmotic pump (CPOP) tablets of diclofenac sodium (DS). The influence of different cores (polymers and osmogens) and coats (thickness and porosigen content) on DS release were studied. Results revealed that decreasing HPMC viscosity grade
  • PMID 24320694

和文文献

  • 一人ひとりの最善を目指すPEGの適応 : 臨床倫理の観点から (北海道胃瘻研究会・日本静脈経腸栄養学会北海道支部合同セミナー 胃瘻の適応と倫理)
  • 胃瘻の適応を考える : PEGのジレンマ、そしてその一歩先へ (北海道胃瘻研究会・日本静脈経腸栄養学会北海道支部合同セミナー 胃瘻の適応と倫理)

関連リンク

経腸栄養法のひとつであるPEG(経皮内視鏡的胃瘻(いろう)造設術)および関連する栄養療法全般についての情報提供を行う、NPO法人PEGドクターズネットワーク(PDN)のホームページです。
PEG用語集 セミナー情報 一般・患者の皆様のページ 2009/05/25 セミナー情報のページに「第4回多摩胃ろうネットワーク市民公開講座」の案内を公開しました 。 日時:2009年6月13日(土) 場所:多摩市関戸公民館 8階会議室 に「第 ...

関連画像

Posted by Very Bored in Catalunya at 7:49 Mixed Media Clipart (A)Clothes peg clip art della peg abbiamo visto che la peg è comeWooden PegFile:Wooden Clothes Peg.jpg


★リンクテーブル★
先読みpneumoencephalography
リンク元胃瘻」「ポリエチレングリコール」「マクロゴール」「気脳撮影」「脳造影法
関連記事peg」「PE」「P

pneumoencephalography」

  [★]

気脳撮影気脳造影

気脳撮影


胃瘻」

  [★]

(治療法)percutaneous endoscopic gastrostomy PEG, (疾患)gastric fistula
胃瘻栄養法胃瘻造設術胃フィステル
  • 経管栄養を目的として胃に造設された栄養瘻である。疾患により胃に穿孔、穿通が生じた場合も胃瘻という言葉が使われる。
  • 適応:経口摂取が不能な場合
  • 管理:瘻孔周囲は自然乾燥させるように努め、湿潤による感染を避ける。チューブの抜去により1日で閉鎖する。


ポリエチレングリコール」

  [★]

polyethylene glycolpolyethyleneglycolPEG
マクロゴール macrogol
Colovate, Colyte, GoLYTELY
(免疫グロブリンの処理)テタノブリンヘブスブリングロベニンヴェノグロブリン
(経口腸管洗浄剤)ムーベンニフプラスニフレック
(軟膏)ウレパールフルコートマクロゴール
トリトンポリオキシエチレン


マクロゴール」

  [★]

macrogol
macrogolum
トリトン tritonポリエチレングリコール polyethylene glycol PEGポリオキシエチレン polyoxyethylene
マクロゴール6000マクロゴール4000マクロゴール400


気脳撮影」

  [★]

cerebral pneumography, pneumoencephalography PEG
気脳造影気脳写
脳室撮影、脳槽造撮影、脳槽造影


脳造影法」

  [★]

encephalography
エンセファログラフィ大脳空気造影法 pneumoencephalography PEG
脳造影


peg」

  [★]

WordNet   license wordnet

「pierce with a wooden pin or knock or thrust a wooden pin into」

WordNet   license wordnet

「stabilize (the price of a commodity or an exchange rate) by legislation or market operations; "The weak currency was pegged to the US Dollar"」

WordNet   license wordnet

「a wooden pin pushed or driven into a surface」
nog

WordNet   license wordnet

「a holder attached to the gunwale of a boat that holds the oar in place and acts as a fulcrum for rowing」
pin, thole, tholepin, rowlock, oarlock

WordNet   license wordnet

「a prosthesis that replaces a missing leg」
wooden leg, leg, pegleg

WordNet   license wordnet

「regulator that can be turned to regulate the pitch of the strings of a stringed instrument」

WordNet   license wordnet

「small markers inserted into a surface to mark scores or define locations etc.」
pin

WordNet   license wordnet

「fasten or secure with a wooden pin; "peg a tent"」
peg down

PrepTutorEJDIC   license prepejdic

「(木などの,おもに木工に用いる)『くぎ』,掛けくぎ;(たるなどの)『せん』;(テントなどの)『くい』 / (弦楽器の弦をしめる)ねじ / 《話》(評価などの)段階)degree) / (議論などの)きっかけ,口実 / 《話》(おもに野球で)送球 / …‘を'『木くぎ』(『くい』)『でとめる』,‘に'木くぎ(木くい)を打つ《+『名』+『down』,+『down』+『名』》 / 〈物価・賃金など〉‘を'仰える,安定させる / 《話》(おもに野球で)〈ボール〉‘を'投げる / 《話》…‘を'認める,見定める」

PE」

  [★]


P」

  [★]


WordNet   license wordnet

「the 16th letter of the Roman alphabet」
p

PrepTutorEJDIC   license prepejdic

「parking」

PrepTutorEJDIC   license prepejdic

「phosphorusの化学記号」


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