出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/02/21 00:36:41」(JST)[Wiki en表示]
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- Pectic polysaccharides of the fresh plum Prunus domestica L. isolated with a simulated gastric fluid and their anti-inflammatory and antioxidant activities.
- Popov SV, Ovodova RG, Golovchenko VV, Khramova DS, Markov PA, Smirnov VV, Shashkov AS, Ovodov YS.SourceInstitute of Physiology, Komi Science Centre, The Urals Branch of the Russian Academy of Sciences, 50, Pervomaiskaya Str., Syktyvkar 167982, Russia. Electronic address: email@example.com.
- Food chemistry.Food Chem.2014 Jan 15;143:106-13. doi: 10.1016/j.foodchem.2013.07.049. Epub 2013 Jul 26.
- A pectic polysaccharide, designated as PD, was extracted from fresh plums (Prunus domestica L.) with a simulated gastric fluid. Galacturonan, which was partially substituted with methyl and O-acetyl ester groups, and rhamnogalacturonan were the main constituents of the linear regions of the sugar ch
- PMID 24054219
- B7-H1 protein vaccine induces protective and therapeutic antitumor responses in SP2/0 myeloma-bearing mice.
- Zhang C, Wang W, Qin X, Xu Y, Huang T, Hao Q, Li W, Wu S, Zhang Y.SourceState Key Laboratory of Cancer Biology, Biotechnology Center, School of Pharmacy, The Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China.
- Oncology reports.Oncol Rep.2013 Nov;30(5):2442-8. doi: 10.3892/or.2013.2686. Epub 2013 Aug 22.
- B7-H1 is a co-inhibitory molecule belonging to the B7 family. The B7-H1 protein is only expressed on macrophage lineage of cells in normal tissues, but is overexpressed in most types of tumor. The aberrant expression of cell surface B7-H1 on cancer cells is generally associated with high-risk progno
- PMID 23970300
- Age-dependent changes in the expression of regulatory cell surface ligands in activated human T-cells.
- Canaday DH, Parker KE, Aung H, Chen HE, Nunez-Medina D, Burant CJ.AbstractBACKGROUND: The immune system consists of multiple preformed and more specific adaptive immune responses, which are all subject to both positive and negative regulation. Programmed cell death protein 1 (PD-1) is a cell surface ligand implicated in the induction of anergy, Inducible T-cell Costimulator (ICOS) plays a stimulatory role in the development of both CD4+ and CD8+ T-cells, Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) plays a role in inhibitory regulation of T-cell activity, and T cell immunoglobulin and mucin protein 3 (Tim-3) has been described as a negative regulatory molecule in CD4+ helper type 1 cells and CD8+ cytotoxic type 1 cells. Each of these ligands is induced with T-cell activation allowing greater opportunity to have a regulatory role.
- BMC immunology.BMC Immunol.2013 Oct 1;14(1):45. [Epub ahead of print]
- BACKGROUND: The immune system consists of multiple preformed and more specific adaptive immune responses, which are all subject to both positive and negative regulation. Programmed cell death protein 1 (PD-1) is a cell surface ligand implicated in the induction of anergy, Inducible T-cell Costimulat
- PMID 24083425
- 第50回米国臨床腫瘍学会(ASCO)年次総会 : 大規模なフェーズⅠ試験が目立ったPD-1/PD-L1阻害剤
- 国際医薬品情報 (1013), 35-44, 2014-07-14
- NAID 40020117456
- 免疫療法 (特集 肺癌 : 診断と治療の進歩) -- (治療)
- 滝口 裕一
- 日本内科学会雑誌 103(6), 1330-1336, 2014-06-10
- NAID 40020123367
- PD-1,PDL-1を標的としたがん治療開発の課題と展望 (特集 注目すべき新標的と期待される次世代抗悪性腫瘍薬)
- 林 秀敏,岡本 勇
- 腫瘍内科 13(6), 767-772, 2014-06
- NAID 40020137122
- What's the next step for researchers focused on PD-1 and PD-L1, the two big targets for checkpoint inhibitors that are now hitting the oncology market?
- The future of PD-1 and PD-L1 inhibition in non-small cell lung cancer (NSCLC) is bright, with ongoing studies suggesting that the strategy will lead to a “new world ...
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