太藤病
WordNet
- an impairment of health or a condition of abnormal functioning
- caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological
PrepTutorEJDIC
- (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
- 女性の話術芸人 =diseur
- 病気にかかった / 病的な,不健全な(morbid)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/06/24 12:12:19」(JST)
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| Eosinophilic folliculitis |
| Classification and external resources |
Eosinophilic folliculitis (also known as "Eosinophilic pustular folliculitis" and "Sterile eosinophilic pustulosis"[1]) is an itchy rash with an unknown cause that is most common among individuals with HIV, though it can occur in HIV-negative individuals where it is known by the eponym Ofuji disease.[2] EF consists of itchy red bumps (papules) centered on hair follicles and typically found on the upper body, sparing the abdomen and legs. The name eosinophilic folliculitis refers to the predominant immune cells associated with the disease (eosinophils) and the involvement of the hair follicles.
Contents
- 1 Epidemiology
- 2 Pathophysiology
- 3 Diagnosis
- 4 Treatment
- 5 See also
- 6 References
Epidemiology
Eosinophilic folliculitis associated with HIV infection typically affects individuals with advanced HIV and low T helper cell counts.[3] It affects both men and women as well as children with HIV and is found throughout the world.
EF may also affect individuals with hematologic disease such as leukemia and lymphoma.[4] It may also affect otherwise normal infants in a self-limited form.[5] HIV-negative individuals can also develop EF — this is more common in Japan.[6]
Pathophysiology
The cause of EF is unknown. A variety of microorganisms have been implicated, including the mite Demodex,[7] the yeast Pityrosporum,[8] and bacteria.[9] An autoimmune process has also been investigated.[10]
Diagnosis
Eosinophilic folliculitis may be suspected clinically when an individual with HIV exhibits the classic symptoms. The diagnosis can be supported by the finding of eosinophilia but a skin biopsy is necessary to establish it. Skin biopsies reveal lymphocytic and eosinophilic inflammation around the hair follicles.
Treatment
Treatment of eosinophilic folliculitis in people with HIV typically begins with the initiation of Highly Active Anti-Retroviral Therapy in order to help reconstitute the immune system. Direct treatment of the EF itself focuses on decreasing the inflammation and itching. Topical corticosteroids and oral antihistamines can alleviate the itching and decrease the size and number of lesions. Treatment with the antifungal drug itraconazole, the antibiotic metronidazole, and the anti-mite drug permethrin may lead to some improvement of symptoms. Other therapies include PUVA, topical tacrolimus, and isotretinoin.[11]
See also
- Eosinophilic pustular folliculitis of infancy
- List of cutaneous conditions
References
- ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
- ^ Ofuji, S; Ogino, A; Horio, T; Oseko, T; Uehara, M (1970). "Eosinophilic pustular folliculitis". Acta dermato-venereologica 50 (3): 195–203. PMID 4193219.
- ^ Parker, SR; Parker, DC; McCall, CO (2006). "Eosinophilic folliculitis in HIV-infected women: case series and review". American journal of clinical dermatology 7 (3): 193–200. doi:10.2165/00128071-200607030-00006. PMID 16734507.
- ^ Patrizi, A; Chieregato, C; Visani, G; Morrone, P; Patrone, P (2004). "Leukaemia-associated eosinophilic folliculitis (Ofuji's disease)". Journal of the European Academy of Dermatology and Venereology : JEADV 18 (5): 596–8. doi:10.1111/j.1468-3083.2004.00982.x. PMID 15324404.
- ^ Buckley, DA; Munn, SE; Higgins, EM (2001). "Neonatal eosinophilic pustular folliculitis". Clinical and experimental dermatology 26 (3): 251–5. doi:10.1046/j.1365-2230.2001.00807.x. PMID 11422167.
- ^ Teraki, Y; Nishikawa, T (2005). "Skin diseases described in Japan 2004". Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 3 (1): 9–25. doi:10.1046/j.1439-0353.2005.04076.x. PMID 16353745.
- ^ Bodokh, I; Lacour, JP; Perrin, C; Bourdet, JF; Ortonne, JP (1994). "Papular eruption in AIDS: role of demodectic mites?". Acta dermato-venereologica 74 (4): 320–2. PMID 7976100.
- ^ Ferrándiz, C; Ribera, M; Barranco, JC; Clotet, B; Lorenzo, JC (1992). "Eosinophilic pustular folliculitis in patients with acquired immunodeficiency syndrome". International Journal of Dermatology 31 (3): 193–5. doi:10.1111/j.1365-4362.1992.tb03934.x. PMID 1568818.
- ^ Smith, KJ; Skelton, HG; Yeager, J; Ruiz, N; Wagner, KF (1995). "Metronidazole for eosinophilic pustular folliculitis in human immunodeficiency virus type 1-positive patients". Archives of dermatology 131 (9): 1089–91. doi:10.1001/archderm.131.9.1089. PMID 7661619.
- ^ Fearfield, LA; Rowe, A; Francis, N; Bunker, CB; Staughton, RC (1999). "Itchy folliculitis and human immunodeficiency virus infection: clinicopathological and immunological features, pathogenesis and treatment". The British journal of dermatology 141 (1): 3–11. doi:10.1046/j.1365-2133.1999.02914.x. PMID 10417509.
- ^ Ellis, E; Scheinfeld, N (2004). "Eosinophilic pustular folliculitis: a comprehensive review of treatment options". American journal of clinical dermatology 5 (3): 189–97. doi:10.2165/00128071-200405030-00007. PMID 15186198.
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Disorders of skin appendages (L60–L75, 703–706)
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| Nail |
- thickness: Onychogryphosis
- Onychauxis
- color: Beau's lines
- Yellow nail syndrome
- Leukonychia
- Azure Lunula
- shape: Koilonychia
- Nail clubbing
- behavior: Onychotillomania
- Onychophagia
- other: Ingrown nail
- Anonychia
- ungrouped: Paronychia
- Chevron nail
- Congenital onychodysplasia of the index fingers
- Green nails
- Half and half nails
- Hangnail
- Hapalonychia
- Hook nail
- Lichen planus of the nails
- Longitudinal erythronychia
- Malalignment of the nail plate
- Median nail dystrophy
- Mees' lines
- Melanonychia
- Muehrcke's lines
- Nail–patella syndrome
- Onychoatrophy
- Onychocryptosis
- Onycholysis
- Onychomadesis
- Onychomatricoma
- Onychomycosis
- Onychophosis
- Onychoptosis defluvium
- Onychorrhexis
- Onychoschizia
- Platonychia
- Pincer nails
- Plummer's nail
- Psoriatic nails
- Pterygium inversum unguis
- Pterygium unguis
- Purpura of the nail bed
- Racquet nail
- Red lunulae
- Shell nail syndrome
- Splinter hemorrhage
- Spotted lunulae
- Staining of the nail plate
- Stippled nails
- Subungual hematoma
- Terry's nails
- Twenty-nail dystrophy
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| Hair |
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| Sweat glands |
| Eccrine |
- Miliaria
- Colloid milium
- Miliaria crystalline
- Miliaria profunda
- Miliaria pustulosa
- Miliaria rubra
- Occlusion miliaria
- Postmiliarial hypohidrosis
- Granulosis rubra nasi
- Ross’ syndrome
- Anhidrosis
- Hyperhidrosis
- Generalized
- Gustatory
- Palmoplantar
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|
| Apocrine |
- Body odor
- Chromhidrosis
- Fox–Fordyce disease
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| Sebaceous |
|
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noco/cong/tumr, sysi/epon
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UpToDate Contents
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- 1. 特定臓器の好酸球性疾患 diseases with eosinophilic involvement of specific organs
- 2. HIV関連好酸球性毛包炎 hiv associated eosinophilic folliculitis
- 3. 毛包炎 folliculitis
English Journal
- Generalized Eosinophilic Pustular Folliculitis of Infancy Responding to Hydroxyzine.
- Lee JH1, Kang JH1, Cho BK1, Park HJ1.
- Annals of dermatology.Ann Dermatol.2015 Aug;27(4):458-60. doi: 10.5021/ad.2015.27.4.458. Epub 2015 Jul 29.
- PMID 26273169
- Eosinophilic folliculitis occurring after stem cell transplant for acute lymphoblastic leukemia: a case report and review.
- Zitelli K1, Fernandes N1, Adams BB1,2.
- International journal of dermatology.Int J Dermatol.2015 Jul;54(7):785-9. doi: 10.1111/ijd.12521. Epub 2014 Jul 11.
- BACKGROUND: Eosinophilic folliculitis (EF) comprises classic eosinophilic pustular folliculitis (EPF), human immunodeficiency virus (HIV)-related EF, and infantile EPF subtypes. A fourth proposed subtype describes EF associated with hematologic malignancy. Recently, EF has occurred after bone marrow
- PMID 25039354
- Vesicles and pustules on the fingers as an initial manifestation of eosinophilic pustular folliculitis.
- Ohata C1, Nii S1, Furumura M1, Nakama T1.
- The Journal of dermatology.J Dermatol.2015 May 25. doi: 10.1111/1346-8138.12946. [Epub ahead of print]
- PMID 26011016
Japanese Journal
- 症例報告 足蹠に膿疱を認め,タクロリムス軟膏が奏効した好酸球性膿疱性毛嚢炎(太藤病)の1例
- Eosinophilic Pustular Folliculitis (Ofuji's Disease) in a Patient with Silicone Tissue Augmentation
- WONG Tak-Wah,TSAI Ya-Ming,LEE J. Yu-Yun,HSU Shih-Tsung,SHEU Hamm-Ming
- Journal of dermatology 31(9), 727-730, 2004-09-01
- NAID 10016259494
- Treatment of eosinophilic pustular folliculitis (Ofuji's disease) with tacrolimus ointment
Related Links
- Ofuji disease symptoms, causes, diagnosis, and treatment information for Ofuji disease (Eosinophilic pustular folliculitis) with alternative diagnoses, full-text book chapters, misdiagnosis, research treatments, prevention, and prognosis. ...
- Eosinophilic folliculitis (also known as "Eosinophilic pustular folliculitis" and "Sterile eosinophilic pustulosis") is an itchy rash with an unknown cause that ... Ofuji's disease is clinically characterized by chronic and recurrent annular ...
- Definition of Ofuji disease in the Medical Dictionary. Ofuji disease explanation. Information about Ofuji disease in Free online English dictionary. What is Ofuji disease? Meaning of Ofuji disease medical term. What does Ofuji forum ...
★リンクテーブル★
[★]
- 英
- eosinophilic pustular folliculitis
- 同
- 好酸球性膿疱性毛嚢炎？、好酸球性膿疱性皮膚症 eosinophilic pustular dermatosis、太藤病 Ofuji disease
- 関
- 好酸球
[★]
- 疾患：illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)
- 特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)
- something that is very wrong with people's attitudes, way of life or with society.
- 関
- ail、ailment、disease entity、disorder、ill、illness、malady、sick、sickness
- disease ≠ illness ≠ disorder