N型電位依存性カルシウムチャネル
WordNet
- direct the flow of; "channel information towards a broad audience" (同)canalize, canalise
- a television station and its programs; "a satellite TV channel"; "surfing through the channels"; "they offer more than one hundred channels" (同)television channel, TV channel
- a passage for water (or other fluids) to flow through; "the fields were crossed with irrigation channels"; "gutters carried off the rainwater into a series of channels under the street"
- (often plural) a means of communication or access; "it must go through official channels"; "lines of communication were set up between the two firms" (同)communication channel, line
- a path over which electrical signals can pass; "a channel is typically what you rent from a telephone company" (同)transmission channel
- a deep and relatively narrow body of water (as in a river or a harbor or a strait linking two larger bodies) that allows the best passage for vessels; "the ship went aground in the channel"
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"
- addicted to a drug (同)dependant, drug-addicted, hooked, strung-out
- contingent on something else (同)dependant, qualified
- (of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence" (同)subordinate
- the rate at which energy is drawn from a source that produces a flow of electricity in a circuit; expressed in volts (同)electromotive_force, emf
- a white metallic element that burns with a brilliant light; the fifth most abundant element in the earths crust; an important component of most plants and animals (同)Ca, atomic number 20
PrepTutorEJDIC
- 〈C〉『水路』(川・湾・運河の船の通行ができる深い部分) / 〈U〉河床・川底 / 〈C〉『海峡』 / 〈C〉みぞ(groove),(道路の)水渠(すいきょ) / 《複数形で》(運搬・伝達の)正式の経路(手続き);(一般に)経路 / 〈C〉(テレビ・ラジオの)チャンネル / …‘に'水路を開く / …‘に'みぞを堀る / …'を'伝える,流す
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
- 『頼っている』,依存している,従属している / 扶養される人(家族)
- 電圧,電圧量,ボルト数
- 『カルシウム』(金属元素;化学記号は『Ca』)
UpToDate Contents
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English Journal
- ZC88, a novel N-type calcium channel blocker from 4-amino-piperidine derivatives state-dependent inhibits Cav2.2 calcium channels.
- Zhang S1, Yang L2, Zhang K1, Liu X1, Dai W1, Zhang C1, Yong Z1, Li J3, Zheng J4.
- Brain research.Brain Res.2015 Apr 24;1605:12-21. doi: 10.1016/j.brainres.2015.01.054. Epub 2015 Feb 12.
- Small molecular inhibitors of Cav2.2 have been reported for the treatment of neuropathic pain; however, low selectivity and side effects limit their further development. In our study, a series of new compounds were designed and synthesized by optimizing the 4-amino-piperidine template. The results s
- PMID 25681549
- Methamphetamine blunts Ca2+ currents and excitatory synaptic transmission through D1/5 receptor-mediated mechanisms in the mouse medial prefrontal cortex.
- González B1, Rivero-Echeto C, Muñiz JA, Cadet JL, García-Rill E, Urbano FJ, Bisagno V.
- Addiction biology.Addict Biol.2015 Apr 14. doi: 10.1111/adb.12249. [Epub ahead of print]
- Psychostimulant addiction is associated with dysfunctions in frontal cortex. Previous data demonstrated that repeated exposure to methamphetamine (METH) can alter prefrontal cortex (PFC)-dependent functions. Here, we show that withdrawal from repetitive non-contingent METH administration (7 days, 1�
- PMID 25871318
- Cacna1c (Cav1.2) Modulates Electroencephalographic Rhythm and Rapid Eye Movement Sleep Recovery.
- Kumar D, Dedic N, Flachskamm C, Voulé S, Deussing JM, Kimura M.
- Sleep.Sleep.2015 Feb 25. pii: sp-00632-14. [Epub ahead of print]
- Study Objectives: The CACNA1C gene encodes the alpha 1C (α1C) subunit of the Cav1.2 voltage-dependent L-type calcium channel (LTCC). Some of the other voltage-dependent calcium channels, e.g., P-/Q-type, Cav2.1; N-type, Cav2.2; E-/R-type, Cav2.3; and T-type, Cav3.3 have been implicated in sleep mod
- PMID 25845695
Japanese Journal
- T-Type Ca Channel Blockade as a Determinant of Kidney Protection
- HAYASHI Koichi,HOMMA Koichiro,WAKINO Shu,TOKUYAMA Hirobumi,SUGANO Naoki,SARUTA Takao,ITOH Hiroshi
- Keio journal of medicine 59(3), 84-95, 2010-09-01
- … Voltage-dependent Ca channels are classified into several subtypes based on the isoform of their α1 subunits. … Traditional Ca channels blockers (CCBs), including nifedipine and amlodipine, act predominantly on L-type Ca channels, whereas novel CCBs such as efonidipine, benidipine and azelnidipine inhibit both L-type and T-type Ca channels. …
- NAID 10029470053
- Suppression of Formalin-Induced Nociception by Cilnidipine, a Voltage-Dependent Calcium Channel Blocker
- Koganei Hajime,Shoji Masataka,Iwata Seinosuke
- Biological and Pharmaceutical Bulletin 32(10), 1695-1700, 2009
- … Cilnidipine is a 1,4-dihydropyridine-derived voltage-dependent calcium channel (VDCC) blocker and suppresses N-type VDCC currents in addition to L-type VDCC currents. … An earlier investigation has suggested that intrathecally injected cilnidipine produces antinociception by blocking N-type VDCCs in mice. …
- NAID 130000116929
- 2 海洋共生藻由来の超炭素鎖有機分子の構造と機能(口頭発表の部)
- 北 将樹,大石 奈央,小西 香織,Han Chunguang,加藤 彰,山野 喜,Siwu Eric R. O.,北村 誠,山田 薫,上村 大輔
- 天然有機化合物討論会講演要旨集 (49), 7-12, 2007-08-24
- … Symbiodinolide (1), a 62-membered novel polyol macrolide with a molecular weight of 2,859 mu, exhibited a potent voltage-dependent N-type calcium ion channel-opening activity at 7 nM. …
- NAID 110006682732
★リンクテーブル★
[★]
- 英
- N-type calcium channel、N-type voltage-dependent calcium channel
- 関
- N-typeカルシウムチャネル、N型電位依存性カルシウムチャネル
[★]
N型カルシウムチャネル、N-typeカルシウムチャネル
- 関
- N-type voltage-dependent calcium channel
[★]
- 英
- N-type voltage-dependent calcium channel
- 関
- N型カルシウムチャネル
[★]
- (windows)ファイル内容表示(linux -> cat])
- ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html
- 関
- form、mode、pattern、type specimen、typed
[★]
- 川床、川底。水路、河道
- 海峡
- 水管、導管
- 溝
- 経路、ルート。道筋、方向
- 関
- ion channel、ionic channel
[★]
- 関
- depend、dependence、dependency、dependently
[★]
- 関
- number of experiment、sample size
- pの前の[n]はmと記載する。synptom→symptom
[★]
- 関
- electric potential、electrical potential、potential