N-ras gene

出典: meddic

N-ras遺伝子

H-ras gene、H-ras oncogene、Ha-ras gene、Ha-ras oncogene、K-ras gene、K-ras oncogene、Ki-ras gene、Ki-ras oncogene、N-ras oncogene、ras gene、ras oncogene

UpToDate Contents

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英文文献

  • Oncogenic mutations in extramammary Paget's disease and their clinical relevance.
  • Kang Z, Xu F, Zhang QA, Wu Z, Zhang X, Xu J, Luo Y, Guan M.SourceDepartment of Laboratory Medicine, Huashan Hospital, Shanghai Medical School, Fudan University, Shanghai 200040, People's Republic of China.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2013 Feb 15;132(4):824-31. doi: 10.1002/ijc.27738. Epub 2012 Aug 7.
  • Extramammary Paget's disease (EMPD) is a rare cutaneous malignant neoplasm. The genetic alterations underlying its pathogenesis have less been described. Therefore, we analyzed the possible mutations in the KRAS, HRAS, NRAS, BRAF, ARAF, RAF1, PIK3CA, AKT1, CTNNB1 and APC genes as well as methylation
  • PMID 22821211
  • Mitogen-activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells to centromere-associated protein E inhibition.
  • Mayes PA, Degenhardt YY, Wood A, Toporovskya Y, Diskin SJ, Haglund E, Moy C, Wooster R, Maris JM.SourceDivision of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA; Department of Pediatrics, Perlman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2013 Feb 1;132(3):E149-57. doi: 10.1002/ijc.27781. Epub 2012 Sep 28.
  • Inhibition of centromere-associated protein-E (CENP-E) has demonstrated preclinical anti-tumor activity in a number of tumor types including neuroblastoma. A potent small molecule inhibitor of the kinesin motor activity of CENP-E has recently been developed (GSK923295). To identify an effective drug
  • PMID 22948716
  • Identification of novel driver tumor suppressors through functional interrogation of putative passenger mutations in colorectal cancer.
  • Zhang L, Komurov K, Wright WE, Shay JW.SourceDepartment of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX.
  • International journal of cancer. Journal international du cancer.Int J Cancer.2013 Feb 1;132(3):732-7. doi: 10.1002/ijc.27705. Epub 2012 Jul 21.
  • Cancer genome sequencing efforts are leading to the identification of genetic mutations in many types of malignancy. However, the majority of these genetic alterations have been considered random passengers that do not directly contribute to tumorigenesis. We have previously conducted a soft agar-ba
  • PMID 22753261

和文文献

  • Effect of common B-RAF and N-RAS mutations on global gene expression in melanoma cell lines
  • <no title>
  • 杉山 武敏,逢坂 光彦
  • 日本疾患モデル学会記録 21, 37-44, 2005
  • … Almost 30% of DMBA- and 16% of TMBA-induced leukemia reveal total or partial trisomy of #2 chromosome (+2 and 2q+, respectively) and many of the rest have normal diploid (2n) karyotype. … Most of these leukemias are erythroblastic leukemia and they reveal a specific mutation of N-ras gene (A → T transversion at the second base of colon 61) . …
  • NAID 130000760629
  • 骨髄増殖症候群におけるN-ras,p53遺伝子の変異の検討
  • 鶴見 茂治
  • Dokkyo journal of medical sciences 30(1), 119-124, 2003-03-25
  • … 加症(polycythemia vera: PV),本態性血小板血症(essential thrombocythemia : ET) ,原発性骨髄線維症(idiopathic myelofibro-sis : MF)が含まれ,骨髄系細胞の慢性的な増殖を主徴とするが,その発症や病期進展に関与する分子病態については未だ不明の点が多い.我々は,本邦のMPD64症例(PV15例,ET38例,MF11例;慢性期例計58例,白血病化例計6例)につき,造血器腫瘍で多く変異がみられるN-rasおよびp53遺伝子の変異についての解析を行った。 …
  • NAID 110000008692

関連リンク

Complete information for NRAS gene (protein-coding), neuroblastoma RAS viral (v-ras) oncogene homolog.
NRAS is an enzyme that in humans is encoded by the NRAS gene. It was discovered by researchers at the Institute of Cancer Research, funded by the Imperial Cancer Research Fund (now Cancer Research UK), and named NRAS, for its ...

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★リンクテーブル★
リンク元ras遺伝子」「N-ras遺伝子」「H-ras gene
関連記事gene」「N」「RAS」「gen」「Nd

ras遺伝子」

  [★]

ras gene
H-ras gene、H-ras oncogene、Ha-ras gene、Ha-ras oncogene、K-ras gene、K-ras oncogene、Ki-ras gene、Ki-ras oncogene、N-ras gene、N-ras oncogene、ras oncogene
  • 低分子量Gタンパク質をコードする癌原遺伝子の一種


N-ras遺伝子」

  [★]

N-ras gene
K-ras遺伝子H-ras遺伝子ras遺伝子、K-ras癌遺伝子、H-ras癌遺伝子Ha-ras遺伝子Ha-ras癌遺伝子Ki-ras遺伝子Ki-ras癌遺伝子ras癌遺伝子N-ras癌遺伝子


H-ras gene」

  [★]

H-ras遺伝子

H-ras oncogene、Ha-ras gene、Ha-ras oncogene、K-ras gene、K-ras oncogene、Ki-ras gene、Ki-ras oncogene、N-ras gene、N-ras oncogene、ras gene、ras oncogene


gene」

  [★] 遺伝子

WordNet   license wordnet

「(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"」
cistron, factor

PrepTutorEJDIC   license prepejdic

「遺伝子」


N」

  [★]

WordNet   license wordnet

「the 14th letter of the Roman alphabet」
n

PrepTutorEJDIC   license prepejdic

「nitrogenの化学記号」


RAS」

  [★]



gen」

  [★]

WordNet   license wordnet

「informal term for information; "give me the gen on your new line of computers"」


Nd」

  [★] ネオジム neodymium

PrepTutorEJDIC   license prepejdic

「neodymiumの化学記号」




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