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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/07/05 00:23:01」(JST)

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Mycobacterium genavense is a slow-growing species of the phylum actinobacteria (Gram-positive bacteria with high guanine and cytosine content, one of the dominant phyla of all bacteria), belonging to the genus mycobacterium.

Description[edit]

Nonmotile, acid-fast coccobacilli (1.0 µm x 2.0 µm). No formation of spores, capsules or aerial hyphae.

Colony characteristics

Tiny, transparent, nonphotochromogenic and dysgonic colonies (on solid Middlebrook 7H11 medium MJ (Allied Laboratories).

Physiology

Slow, fastidious growth in liquid media within 3–12 weeks at 31°C, 37°C and 42°C, with slightly better growth at 45°C.
Primary cultures for isolation require liquid broth media such as BACTEC 12B medium, Middlebrook 7H9 medium.
Acid broth media such as, BACTEC pyrazinamidase test medium, may facilitate primary isolation.
No growth on standard solid media like Löwenstein-Jensen, unsupplemented Middlebrook 7H11 or Middlebrook 7H10 media.
Visible growth on solid Middlebrook 7H11 medium supplemented with MJ after inoculation with a broth culture within 3–9 weeks.
Susceptible to streptomycin and rifampicin
Resistant to isoniazid and ethambutol

Differential characteristics

Differentiation from other slowly growing mycobacteria by its fastidious growth.
Closely related to M. simiae by evaluation of 16S rDNA sequences.

Pathogenesis[edit]

Opportunistic pathogen. Clinically indistinguishable from generalised infections in patients with AIDS due to M. avium complex strains, but more related to gastro-intestinal disorders.
Most common cause of mycobacterial disease in parrots and parakeets.

Type strain[edit]

Strain 2289 = ATCC 51234

References[edit]

Böttger et al. 1993. Mycobacterium genavense sp. nov. Int. J. Syst. Bacteriol., 43, 841-843.

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UpToDate Contents

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1. HIV感染患者における非結核性抗酸菌（MACを除く）の概要 overview of nontuberculous mycobacteria excluding mac in hiv infected patients
2. 非結核性抗酸菌の微生物学 microbiology of nontuberculous mycobacteria

English Journal

Disseminated Mycobacterium genavense infection in a chinchilla (Chinchilla lanigera).

Huynh M1, Pingret JL2, Nicolier A3.
Journal of comparative pathology.J Comp Pathol.2014 Jul;151(1):122-5. doi: 10.1016/j.jcpa.2014.03.003. Epub 2014 Mar 14.
A 1-year-old neutered male chinchilla (Chinchilla lanigera) was presented with emaciation and a 1-month history of progressive weight loss. The animal was bright and responsive on clinical examination, but had poor body condition. Serum biochemical analysis revealed elevated alanine amino transferas
PMID 24813153

Disseminated Mycobacterium genavense infection in a patient with immunosuppressive therapy and lymphoproliferative malignancy.

Numbi N, Demeure F, Van Bleyenbergh P, De Visscher N.
Acta clinica Belgica.Acta Clin Belg.2014 Apr;69(2):142-5. doi: 10.1179/0001551213Z.00000000016.
We present the case of a 51-year-old woman who presented a right supraclavicular mass corresponding to lymphadenitis with atypical mycobacterium (Mycobacterium genavense). Later, she developed subcutaneous purulent small nodules containing the same germ. The presence of this mycobacterium was in the
PMID 24724760

Japanese Journal

AIDS患者における播種性非結核性抗酸菌症 (Mycobacterium genavense) の1例

新野大介,松木啓,田中健之,柳原克紀,大楠清文,林徳真吉,今泉芳孝,宮崎泰司,有吉紅也,大島孝一
診断病理 : Japanese journal of diagnostic pathology 28(1), 18-20, 2011-01-31
NAID 10028288045

症例報告原発性免疫不全症患者に合併したMycobacterium genavense感染による多発脳病変の1例

内野晴登,寺坂俊介,山口秀 [他]
Brain and nerve 63(1), 79-83, 2011-01
NAID 40017442190

「ラニヨン分類」

Mycobacterium genavense
Scientific classification
Kingdom:	Bacteria
Phylum:	Actinobacteria
Order:	Actinomycetales
Suborder:	Corynebacterineae
Family:	Mycobacteriaceae
Genus:	Mycobacterium
Species:	M. genavense
Binomial name
	Mycobacterium genavense; Böttger et al. 1993, ATCC 51234

　　[★]

英: Runyon classification
同: Runyon分類
関: 抗酸菌

[show details]

ラニアン分類 : 1 件
ラニャン分類 : nothing
ラニヤン分類 : 
ラニョン分類 : 
ラニヨン分類 : 4 件

ラニアン分類 Runyon : nothing
ラニャン分類 Runyon : nothing
ラニヤン分類 Runyon : 
ラニョン分類 Runyon : 
ラニヨン分類 Runyon : 3 件

分類				菌種名
培養可能菌	遅発育菌	結核菌群		Mycobacterium tuberculosis
				Mycobacterium bovis
				Mycobacterium microti
				Mycobacterium africanum
		非結核性抗酸菌群	I群菌光発色菌	Mycobacterium kansasii
				Mycobacterium marinum
				Mycobacterium simiae
				Mycobacterium asiaticum
			II群菌暗発色菌	Mycobacterium flavescens
				Mycobacterium gordonae
				Mycobacterium scrofulaceum
				Mycobacterium szulgai
			III群菌非光発色菌	Mycobacterium avium complex
				Mycobacterium celatum
				Mycobacterium haemophilum
				Mycobacterium gastri
				Mycobacterium genavense
				Mycobacterium malmoense
				Mycobacterium nonchromogenicum
				Mycobacterium shimoidei
				Mycobacterium terrae
				Mycobacterium trivale
				Mycobacterium ulcerans
				Mycobacterium xenopi
	迅速発育菌		IV群菌	Mycobacterium abscessus
				Mycobacterium fortuitum group
				Mycobacterium chelonae group
				Mycobacterium phlei
				Mycobacterium smegmatis
				Mycobacterium vaccae
培養不能菌				Mycobacterium leprae

参考

http://www.jata.or.jp/rit/rj/319kataki10.pdf#search='%E8%BF%85%E9%80%9F%E7%99%BA%E8%82%B2%E7%BE%A4+rapid+group'

「Mycobacterium」

　　[★] マイコバクテリウム属

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案内

案内

Mycobacterium genavense