MIDD

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/09/14 14:53:10」(JST)

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英文文献

  • Myeloma-related Kidney Disease.
  • Leung N1, Nasr SH2.Author information 1Division of Nephrology and Hypertension, and Hematology, Mayo Clinic, Rochester, MN; and Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN. Electronic address: leung.nelson@mayo.edu.2Division of Nephrology and Hypertension, and Hematology, Mayo Clinic, Rochester, MN; and Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.AbstractMultiple myeloma is a malignant plasma cell disorder characterized by the overproduction of monoclonal proteins. The kidney is 1 of the major target organs of multiple myeloma. Most often, this is the result of the monoclonal proteins, which can injure the kidney via several mechanisms. In some cases, direct invasion by myeloma cells and/or bone marrow cells can also result in kidney injury. A kidney biopsy can help distinguish the various myeloma-related kidney diseases and aid in the treatment plan.
  • Advances in chronic kidney disease.Adv Chronic Kidney Dis.2014 Jan;21(1):36-47. doi: 10.1053/j.ackd.2013.08.009.
  • Multiple myeloma is a malignant plasma cell disorder characterized by the overproduction of monoclonal proteins. The kidney is 1 of the major target organs of multiple myeloma. Most often, this is the result of the monoclonal proteins, which can injure the kidney via several mechanisms. In some case
  • PMID 24359985
  • A review of maternally inherited diabetes and deafness.
  • Li HZ1, Li RY1, Li M2.Author information 1Institute for Integrated Traditional and Western Medicine, the Second Affiliated Hospital of Xingtai Medical College, Xingtai 054000, Hebei Province, China.2Department of Health, Hotan Detachment of the Xinjiang Armed Police Corps, Hotan 848011, Xinjiang Uygur Autonomous Region, China.AbstractMaternally inherited diabetes and deafness (MIDD), a mitochondrial disease first described in 1992, results from the mitochondrial DNA mutation and affects up to 1% of the patients with diabetes. This review discusses the biomedical mechanisms of MIDD patients; summarizes the recent improvement of clinical and genetic diagnosis of MIDD; outlines the advances of the clinical management of these patients and their families.
  • Frontiers in bioscience (Landmark edition).Front Biosci (Landmark Ed).2014 Jan 1;19:777-82.
  • Maternally inherited diabetes and deafness (MIDD), a mitochondrial disease first described in 1992, results from the mitochondrial DNA mutation and affects up to 1% of the patients with diabetes. This review discusses the biomedical mechanisms of MIDD patients; summarizes the recent improvement of c
  • PMID 24389221
  • The m.3243A>G mitochondrial DNA mutation and related phenotypes. A matter of gender?
  • Mancuso M, Orsucci D, Angelini C, Bertini E, Carelli V, Comi GP, Donati A, Minetti C, Moggio M, Mongini T, Servidei S, Tonin P, Toscano A, Uziel G, Bruno C, Ienco EC, Filosto M, Lamperti C, Catteruccia M, Moroni I, Musumeci O, Pegoraro E, Ronchi D, Santorelli FM, Sauchelli D, Scarpelli M, Sciacco M, Valentino ML, Vercelli L, Zeviani M, Siciliano G.Author information Neurological Clinic, University of Pisa, Via Roma 67, 56100, Pisa, Italy, mancusomichelangelo@gmail.com.AbstractThe m.3243A>G "MELAS" (mitochondrial encephalopathy with lactic acidosis and stroke-like episodes) mutation is one of the most common point mutations of the mitochondrial DNA, but its phenotypic variability is incompletely understood. The aim of this study was to revise the phenotypic spectrum associated with the mitochondrial m.3243A>G mutation in 126 Italian carriers of the mutation, by a retrospective, database-based study ("Nation-wide Italian Collaborative Network of Mitochondrial Diseases"). Our results confirmed the high clinical heterogeneity of the m.3243A>G mutation. Hearing loss and diabetes were the most frequent clinical features, followed by stroke-like episodes. "MIDD" (maternally-inherited diabetes and deafness) and "PEO" (progressive external ophthalmoplegia) are nosographic terms without any real prognostic value, because these patients may be even more prone to the development of multisystem complications such as stroke-like episodes and heart involvement. The "MELAS" acronym is convincing and useful to denote patients with histological, biochemical and/or molecular evidence of mitochondrial disease who experience stroke-like episodes. Of note, we observed for the first time that male gender could represent a risk factor for the development of stroke-like episodes in Italian m.3243A>G carriers. Gender effect is not a new concept in mitochondrial medicine, but it has never been observed in MELAS. A better elucidation of the complex network linking mitochondrial dysfunction, apoptosis, estrogen effects and stroke-like episodes may hold therapeutic promises.
  • Journal of neurology.J Neurol.2013 Dec 29. [Epub ahead of print]
  • The m.3243A>G "MELAS" (mitochondrial encephalopathy with lactic acidosis and stroke-like episodes) mutation is one of the most common point mutations of the mitochondrial DNA, but its phenotypic variability is incompletely understood. The aim of this study was to revise the phenotypic spectrum as
  • PMID 24375076

和文文献

  • アミロイド腎症とMonoclonal Immunoglobulin Deposition Disease (MIDD) (特集 ネフローゼ症候群)
  • The Japanese journal of nephrology = 日本腎臓学会誌 56(4), 493-499, 2014
  • NAID 40020126085
  • 単クローン性免疫グロブリン関連腎症―特にproliferative glomerulonephritis with monoclonal IgG deposits について
  • 網羅的解析により診断された耳小骨奇形を合併したミトコンドリア3243変異例

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maternal-inherited diabetes with deafness」

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MIDD
MIDD


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「Michigan / Military Intelligence 陸軍情報部」


MID」

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multiinfarct dementia,多発梗塞性認知症


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