MHC class II gene

• MHCクラスII遺伝子

関

class II gene、HLA class II gene、immune response gene、Ir gene

WordNet

1. elegance in dress or behavior; "she has a lot of class"
2. a collection of things sharing a common attribute; "there are two classes of detergents" (同)category, family
3. a league ranked by quality; "he played baseball in class D for two years"; "Princeton is in the NCAA Division 1-AA" (同)division
4. a body of students who are taught together; "early morning classes are always sleepy" (同)form, grade, course
5. people having the same social, economic, or educational status; "the working class"; "an emerging professional class" (同)stratum, social_class, socio-economic class
6. a body of students who graduate together; "the class of 97"; "she was in my year at Hoehandle High" (同)year
7. (biology) a taxonomic group containing one or more orders
8. the 9th letter of the Roman alphabet (同)i
9. (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
10. the 13th letter of the Roman alphabet (同)m

PrepTutorEJDIC

1. 〈C〉(何らかの類似性を持つ)(…の)『種類』,類(sort, kind)《+『of』+『名』》 / 〈C〉《集合的に》《単数扱い》『クラス』,学級,組 / 〈U〉〈C〉(クラス単位の)『授業』;授業時間 / 〈C〉《米》《集合的に》(主に高校・大学の)同期生 / 〈C〉《しばしば複数形で》(同程度の教育・経済力・社会的地位などを持つ)『階級』,階層 / 〈C〉(交通機関などの)『等級』 / 〈C〉(英国の大学の)試験の合格等級 / 〈C〉綱(こう)(動植物の分類で門(phylum, division)と目(もく)(order)の間) / 〈U〉《話》(その人の社会的地位を高く見せる)風格 / …'を'(…の)部類に入れる《+『名』+『among』(『with』)+『名』》,(…として)…'を'分類する《+『名』+『as』+『名』》
2. 『私は』私が
3. iodineの化学記号
4. 遺伝子
5. Mach number / mark[s] / Monsieur

UpToDate Contents

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English Journal

• Alternative Activation of Human Plasmacytoid DCs In Vitro and in Melanoma Lesions: Involvement of LAG-3.

• Camisaschi C1, De Filippo A1, Beretta V1, Vergani B2, Villa A2, Vergani E1, Santinami M3, Cabras AD4, Arienti F5, Triebel F6, Rodolfo M1, Rivoltini L1, Castelli C1.
• The Journal of investigative dermatology.J Invest Dermatol.2014 Jul;134(7):1893-902. doi: 10.1038/jid.2014.29. Epub 2014 Jan 17.
• Plasmacytoid dendritic cells (pDCs) at tumor sites are often tolerogenic. Although pDCs initiate innate and adaptive immunity upon Toll-like receptor (TLR) triggering by pathogens, TLR-independent signals may be responsible for pDC activation and immune suppression in the tumor inflammatory environm
• PMID 24441096

• PCR-based isolation of multigene families: lessons from the avian MHC class IIB.

• Burri R1, Promerová M, Goebel J, Fumagalli L.
• Molecular ecology resources.Mol Ecol Resour.2014 Jul;14(4):778-88. doi: 10.1111/1755-0998.12234. Epub 2014 Mar 7.
• The amount of sequence data available today highly facilitates the access to genes from many gene families. Primers amplifying the desired genes over a range of species are readily obtained by aligning conserved gene regions, and laborious gene isolation procedures can often be replaced by quicker P
• PMID 24479469

• Ultra-deep Illumina sequencing accurately identifies MHC class IIb alleles and provides evidence for copy number variation in the guppy (Poecilia reticulata).

• Lighten J1, van Oosterhout C, Paterson IG, McMullan M, Bentzen P.
• Molecular ecology resources.Mol Ecol Resour.2014 Jul;14(4):753-67. doi: 10.1111/1755-0998.12225. Epub 2014 Feb 5.
• We address the bioinformatic issue of accurately separating amplified genes of the major histocompatibility complex (MHC) from artefacts generated during high-throughput sequencing workflows. We fit observed ultra-deep sequencing depths (hundreds to thousands of sequences per amplicon) of allelic va
• PMID 24400817

Japanese Journal

• Expansion of viral variants associated with immune escape and impaired virion secretion in patients with HBV reactivation after resolved infection

• Inuzuka Tadashi,Ueda Yoshihide,Arasawa Soichi,Takeda Haruhiko,Matsumoto Tomonori,Osaki Yukio,Uemoto Shinji,Seno Hiroshi,Marusawa Hiroyuki
• Scientific Reports (8), 2018-12-24
• … Ultra-deep sequencing revealed that the prevalence of genotype B and the ratio of non-synonymous to synonymous evolutionary changes in the surface (S) gene were significantly higher in non-HSCT cases than in patients with HSCT. … Those non-synonymous variants included immune escape (6/16 cases) and MHC class II-restricted T-cell epitope variants (6/16 cases). …
• NAID 120006719417

• Genetic diversity of MHC class II DRB alleles in the continental and Japanese populations of the sable Martes zibellina (Mustelidae, Carnivora, Mammalia)

• Nishita Yoshinori,Abramov Alexei V,Murakami Takahiro,Masuda Ryuichi
• Mammal Research 63(3), 369-378, 2018-07
• … To further understand the molecular evolution of the major histocompatibility complex (MHC), we sequenced part of exon 2 in MHC class II DRB genes, including codons encoding the antigen binding site, from 33 individuals from continental Eurasia and Japan. …
• NAID 120006649183

• 実験的自己免疫視神経炎のメカニズム解析および抗MOG抗体陽性視神経炎の解析

• 松田 隆作
• 神経眼科 35(4), 379-388, 2018
• … は21日目に有意に延長した．軸索変性は14日より早く観察され，ミクログリアの浸潤は，T細胞が浸潤する前の免疫14日目に観察され，21日目には脱髄が観察された．さらに，神経ペプチドの一種であるcalcitonin gene-related peptide（CGRP）遺伝子導入樹状細胞はEAON/EAEの発症を抑制し，その抑制機序にIL-10が関与していることを明らかにした．また，我々はIL-10遺伝子導入樹状細胞がEAON/EAEを抑制することも明らかにし，その奏功 …
• NAID 130007556785

Related Links

• Regulation of MHC class II gene expression by the class II ...

Figure 1 | Regulation of the transcription of MHC class II genes. The SXY module that is present in all classical MHC class II genes — as well as in the genes encoding invariant chain (Ii), HLA-DM, HLA-DO and MHC ...

• Regulation of MHC class I and II gene transcription ...

1. Immunogenetics. 1998 Aug;48(3):208-21. Regulation of MHC class I and II gene transcription: differences and similarities. van den Elsen PJ, Gobin SJ, van Eggermond MC, Peijnenburg A. Major histocompatibility ...

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★リンクテーブル★

リンク元	「class II gene」「HLA class II gene」「immune response gene」「MHCクラスII遺伝子」
関連記事	「class」「II」「I」「MHC class」「MH」

「class II gene」

　　[★]

• クラスII遺伝子

関

HLA class II gene、immune response gene、Ir gene、MHC class II gene

「HLA class II gene」

　　[★]

• HLAクラスII遺伝子

関

class II gene、immune response gene、Ir gene、MHC class II gene

「immune response gene」

　　[★]

• 免疫応答遺伝子

関

class II gene、HLA class II gene、Ir gene、MHC class II gene

「MHCクラスII遺伝子」

　　[★]

英

MHC class II gene

関

MHC

「class」

　　[★]

• n.

• クラス、分類、種類、部門、(分類学)綱

関

assortment、branch、categorization、categorize、category、classification、classifier、classify、department、division、group、grouping、kind、pattern、section、sector、sort、systematization、typing

　 　 　 　 　 　 　 　

「II」

　　[★]

• 蛍光像増倍管 image intensifier
• インスリン分泌指数 インスリノゲニック・インデックス insulinogenic index
• 黄疸指数 icterus index

「I」

　　[★]

• イソロイシン isoleucine
• イノシン inosine
• 阻害剤 inhibitor
• iodine
• ヨード iodide
• I因子 factor I

　 　 　

「MHC class」

　　[★]

• 主要組織適合抗原クラス、MHCクラス

関

major histocompatibility complex class

「MH」

　　[★]

• 悪性高体温症 malignant hyperthermia
• 月経歴 menstrual history