カゼイ菌

関: Lactobacillus casei

WordNet

look over, usually with the intention to rob; "They men cased the housed"
the quantity contained in a case (同)caseful
a specific state of mind that is temporary; "a case of the jitters"
(printing) the receptacle in which a compositor has his type, which is divided into compartments for the different letters, spaces, or numbers; "for English, a compositor will ordinarily have two such cases, the upper case containing the capitals and the lower case containing the small letters" (同)compositor''s case, typesetter''s case
a glass container used to store and display items in a shop or museum or home (同)display case, showcase, vitrine
bed linen consisting of a cover for a pillow; "the burglar carried his loot in a pillowcase" (同)pillowcase, slip, pillow slip
a portable container for carrying several objects; "the musicians left their instrument cases backstage"
nouns or pronouns or adjectives (often marked by inflection) related in some way to other words in a sentence (同)grammatical case
an occurrence of something; "it was a case of bad judgment"; "another instance occurred yesterday"; "but there is always the famous example of the Smiths" (同)instance, example
a person requiring professional services; "a typical case was the suburban housewife described by a marriage counselor"
a problem requiring investigation; "Perry Mason solved the case of the missing heir"
a statement of facts and reasons used to support an argument; "he stated his case clearly"
the actual state of things; "that was not the case"
the 12th letter of the Roman alphabet (同)l

PrepTutorEJDIC

〈C〉(…の)『実例』,事例《+『of』+『名』》 / 《the case》『実情』,真相 / 〈C〉〈U〉『場合』,情況,事情,立場 / 〈C〉(…の)(決定すべき)問題,重大事《+『of』+『名』》 / 〈C〉『訴訟』[『事件』],裁判 / 〈C〉(正当な)論拠,弁護;(被告または原告の)主張,申し立て / 〈C〉病状,容態;(症状から見た)患者 / 〈C〉〈U〉格(名詞・代名詞の語形変化)
(運搬・保管用のいろいろな)『箱』,ケース / (各種の)『容器』,筒,さや,袋,おおい / (標本・陳列用の)ガラス箱,戸だな / (戸・窓などの)わく / 活字箱 / …'を'箱(袋,さやなど)に入れる《+『名』+『up,』+『名』+『up』》
lira(イタリアの貨幣単位リラ)
liter[s]

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/07/23 13:29:19」(JST)

wiki en

[Wiki en表示]

Lactobacillus casei is a species of genus Lactobacillus found in the human intestine and mouth. This particular species of Lactobacillus is documented to have a wide pH and temperature range, and complements the growth of L. acidophilus, a producer of the enzyme amylase (a carbohydrate-digesting enzyme).

Uses

Dairy

The most common application of L. casei is industrial, specifically for dairy production.

L. casei is typically the dominant species of nonstarter lactic acid bacteria (i.e. contaminant bacteria^[1]) present in ripening cheddar cheese, and, recently, the complete genome sequence of L. casei ATCC 334 has become available. L. casei is also the dominant species in naturally fermented Sicilian green olives.^[2]

Medical

A commercial beverage containing L. casei strain Shirota has been shown to inhibit the growth of Helicobacter pylori in vivo. But, when the same beverage was consumed by humans in a small trial, H. pylori colonization decreased only slightly, and the trend was not statistically significant.^[3] Some L. casei strains are considered to be probiotic, and may be effective in alleviation of gastrointestinal pathogenic bacterial diseases. According to World Health Organization, those properties have to be demonstrated on each specific strain—including human clinical studies—to be valid.^[4] L. casei has been combined with other probiotic strains of bacteria in randomized trials studying its effects in preventing antibiotic-associated diarrhea (AAD) and Clostridium difficile infections (CDI) and patients in the trials who were not given the placebo had significantly lower rates of AAD or CDI (depending on the trial) with no adverse effects reported.^[5] Additionally, trials have shown significantly shorter recovery times in children suffering from acute diarrhea (primarily caused by rotavirus) when given different L. casei treatments when compared to placebo.^[6] Studies suggest that Lactobacillus is a safe and effective treatment for acute and infectious diarrhea.^[7] In the preparation of food, L. casei bacteria can be used in the natural fermentation of beans to lower levels of the compounds causing flatulence upon digestion.^[8] Pancreatic necrosis if left untreated has an almost 100 percent fatality rate due to bacterial translocation. Lactobacillus casei has been found to have a wide spectrum of coverage against pathogenic organisms that translocate from the gastrointestinal tract thereby demonstrating therapeutic benefit in pancreatic necrosis. The addition of other probiotic strains reduces pro-inflammatory cytokines and further suppresses bacterial overgrowth in the small intestine leading to a reduction in bacterial translocation.^[9] Administration of lactobacillus casei prior to an inflammatory insult to the bowel prevents the development of increased intestinal permeability.^[10]^[11]

Commercial probiotic

Among the best-documented, probiotics L.casei, L. casei DN-114001, and L. casei Shirota have been extensively studied^[12] and are widely available as BIO-K Plus functional foods (see Actimel, Yakult).

Other

In the past few years, there have been many studies in the decolorization of azo dyes by lactic acid bacteria such as L. casei TISTR 1500, L. paracasei, Oenococcus oeni, etc. With the azoreductase activity, mono-, di- azo bonds are degraded completely, and generate other aromatic compounds as intermediates.^[13]

References

^ Banks JM, Williams AG; Williams (2004). "The role of the nonstarter lactic acid bacteria in Cheddar cheese ripening". International Journal of Dairy Technology 57 (2–3): 145–152. doi:10.1111/j.1471-0307.2004.00150.x. Retrieved 2013-10-30.
^ Randazzo CL, Restuccia C, Romano AD, Caggia C; Restuccia; Romano; Caggia (January 2004). "Lactobacillus casei, dominant species in naturally fermented Sicilian green olives DORITOS". Int. J. Food Microbiol. 90 (1): 9–14. doi:10.1016/S0168-1605(03)00159-4. PMID 14672826.
^ Cats A, Kuipers EJ, Bosschaert MA, Pot RG, Vandenbroucke-Grauls CM, Kusters JG; Kuipers; Bosschaert; Pot; Vandenbroucke-Grauls; Kusters (February 2003). "Effect of frequent consumption of a Lactobacillus casei-containing milk drink in Helicobacter pylori-colonized subjects". Aliment. Pharmacol. Ther. 17 (3): 429–35. doi:10.1046/j.1365-2036.2003.01452.x. PMID 12562457.
^ "Joint FAO/WHO Working Group Report on Drafting Guidelines for the Evaluation of Probiotics in Food" (PDF). London, Ontario, Canada. April 30 – May 1, 2002.
^ McFarland, LV (2009). "Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections" (PDF). Anaerobe 15 (6): 274–80. doi:10.1016/j.anaerobe.2009.09.002. PMID 19825425. Retrieved 2012-04-15.
^ Isolauri, Erika;; et al. (1991). "A Human Lactobacillus Strain (Lactobacillus casei sp strain GG) Promotes Recovery From Acute Diarrhea in Children". Pediatrics 88 (1): 90–97. PMID 1905394. Retrieved 2012-04-15.
^ Van Niel, C. W.; Feudtner, C.; Garrison, M. M.; Christakis, D. A. (2002). "Lactobacillus Therapy for Acute Infectious Diarrhea in Children: A Meta-analysis". Pediatrics 109 (4): 678–684. doi:10.1542/peds.109.4.678. PMID 11927715.
^ Marisela Granito, Glenda Álvarez; Álvarez (June 2006). "Lactic acid fermentation of black beans (Phaseolus vulgaris): microbiological and chemical characterization". Journal of the Science of Food and Agriculture 86 (8): 1164–1171. doi:10.1002/jsfa.2490.
^ Ridwan, BU.; Koning, CJ.; Besselink, MG.; Timmerman, HM.; Brouwer, EC.; Verhoef, J.; Gooszen, HG.; Akkermans, LM. (Jan 2008). "Antimicrobial activity of a multispecies probiotic (Ecologic 641) against pathogens isolated from infected pancreatic necrosis" (PDF). Lett Appl Microbiol 46 (1): 61–7. doi:10.1111/j.1472-765X.2007.02260.x. PMID 17944834.
^ Eun, CS.; Kim, YS.; Han, DS.; Choi, JH.; Lee, AR.; Park, YK. (Jan 2011). "Lactobacillus casei prevents impaired barrier function in intestinal epithelial cells". APMIS 119 (1): 49–56. doi:10.1111/j.1600-0463.2010.02691.x. PMID 21143526.
^ Zakostelska, Z.; Kverka, M.; Klimesova, K.; Rossmann, P.; Mrazek, J.; Kopecny, J.; Hornova, M.; Srutkova, D.; et al. (2011). "Lysate of probiotic Lactobacillus casei DN-114 001 ameliorates colitis by strengthening the gut barrier function and changing the gut microenvironment". PLOS ONE 6 (11): e27961. doi:10.1371/journal.pone.0027961. PMC 3222668. PMID 22132181.
^ Kazuyoshi Takeda; Ko Okumura. "Effects of a Fermented Milk Drink Containing Lactobacillus casei Strain Shirota on the Human NK-Cell Activity".
^ Seesuriyachan P, Takenaka S, Kuntiya A, Klayraung S, Murakami S, Aoki K; Takenaka; Kuntiya; Klayraung; Murakami; Aoki (March 2007). "Metabolism of azo dyes by Lactobacillus casei TISTR 1500 and effects of various factors on decolorization". Water Res. 41 (5): 985–92. doi:10.1016/j.watres.2006.12.001. PMID 17254626.

UpToDate Contents

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1. アレルギー疾患の治療のためのプレバイオティクスおよびプロバイオティクス prebiotics and probiotics for treatment of allergic disease
2. クロストリジウム・ディフィシルとプロバイオティクス clostridium difficile and probiotics
3. 消化器疾患に対するプロバイオティクス probiotics for gastrointestinal diseases
4. 小腸内細菌過剰繁殖の治療 treatment of small intestinal bacterial overgrowth
5. 幼児および小児における慢性機能性便秘および便失禁：治療 chronic functional constipation and fecal incontinence in infants and children treatment

English Journal

Potentiation by metal ions of the efficacy of the ionophores, monensin and tetronasin, towards four species of ruminal bacteria.

Newbold CJ, Wallace RJ, Walker-Bax ND.SourceRowett Institute of Nutrition and Health, University of Aberdeen, Bucksburn, Aberdeen, UK.
FEMS microbiology letters.FEMS Microbiol Lett.2013 Jan;338(2):161-7. doi: 10.1111/1574-6968.12044. Epub 2012 Dec 4.
Concentrations of Na(+) , K(+) and Ca(2+) in the growth medium were varied within limits normally found in vivo to determine how cation concentrations affect the sensitivity of ruminal bacteria to the ionophores, monensin (a Na(+) /H(+) and K(+) /H(+) exchanger) and tetronasin (Ca(2+) /H(+) ). H
PMID 23210858

Lactobacillus casei and Lactobacillus acidophilus Regulate Inflammatory Pathway and Improve Antioxidant Status in Collagen-Induced Arthritic Rats.

Amdekar S, Singh V, Kumar A, Sharma P, Singh R.Source1 Department of Microbiology, Barkatullah University , Bhopal, Madhya Pradesh, India .
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.J Interferon Cytokine Res.2013 Jan;33(1):1-8. doi: 10.1089/jir.2012.0034. Epub 2012 Oct 2.
In view of well-established immunomodulatory properties of Lactobacillus, present investigation was carried out to evaluate antioxidant and anti-inflammatory potential of Lactobacillus casei and Lactobacillus acidophilus, against inflammatory pathway and oxidative stress developed in an experimental
PMID 23030670

Japanese Journal

プロバイオティクス (特集上気道感染症を科学する) -- (民間療法,予防方法に効果はあるか)

日本胸部臨床 75(9), 994-997, 2016-09
NAID 40020952949

High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice

2016-07-04
NAID 120005818448

清酒酵母研究の歩み

東京農業大学農学集報 60(4), 205-211, 2016-03-15
NAID 110010016586

「カゼイ菌」

Lactobacillus casei
	Yakult, a drink containing Lactobacillus casei
Scientific classification
Domain:	Bacteria
Phylum:	Firmicutes
Class:	Bacilli
Order:	Lactobacillales
Family:	Lactobacillaceae
Genus:	Lactobacillus
Species:	L. casei
Binomial name
	Lactobacillus casei; (Orla-Jensen 1916); Hansen & Lessel 1971

　　[★]

ラ: Lactobacillus casei、L. casei
関: ラクトバチルス・カゼイ

「Lactobacillus casei」

　　[★]

ラクトバチルス・カゼイ、カゼイ菌

関: L. casei

「case」

　　[★]

n.

ケース、場合、事、症例

関: circumstance、event、instance、occasion

「L」

　　[★]

[1] Banks JM, Williams AG; Williams (2004). "The role of the nonstarter lactic acid bacteria in Cheddar cheese ripening". International Journal of Dairy Technology 57 (2–3): 145–152. doi:10.1111/j.1471-0307.2004.00150.x. Retrieved 2013-10-30.

[2] Randazzo CL, Restuccia C, Romano AD, Caggia C; Restuccia; Romano; Caggia (January 2004). "Lactobacillus casei, dominant species in naturally fermented Sicilian green olives DORITOS". Int. J. Food Microbiol. 90 (1): 9–14. doi:10.1016/S0168-1605(03)00159-4. PMID 14672826.

[3] Cats A, Kuipers EJ, Bosschaert MA, Pot RG, Vandenbroucke-Grauls CM, Kusters JG; Kuipers; Bosschaert; Pot; Vandenbroucke-Grauls; Kusters (February 2003). "Effect of frequent consumption of a Lactobacillus casei-containing milk drink in Helicobacter pylori-colonized subjects". Aliment. Pharmacol. Ther. 17 (3): 429–35. doi:10.1046/j.1365-2036.2003.01452.x. PMID 12562457.

[4] "Joint FAO/WHO Working Group Report on Drafting Guidelines for the Evaluation of Probiotics in Food" (PDF). London, Ontario, Canada. April 30 – May 1, 2002.

[5] McFarland, LV (2009). "Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infections" (PDF). Anaerobe 15 (6): 274–80. doi:10.1016/j.anaerobe.2009.09.002. PMID 19825425. Retrieved 2012-04-15.

[6] Isolauri, Erika;; et al. (1991). "A Human Lactobacillus Strain (Lactobacillus casei sp strain GG) Promotes Recovery From Acute Diarrhea in Children". Pediatrics 88 (1): 90–97. PMID 1905394. Retrieved 2012-04-15.

[7] Van Niel, C. W.; Feudtner, C.; Garrison, M. M.; Christakis, D. A. (2002). "Lactobacillus Therapy for Acute Infectious Diarrhea in Children: A Meta-analysis". Pediatrics 109 (4): 678–684. doi:10.1542/peds.109.4.678. PMID 11927715.

[8] Marisela Granito, Glenda Álvarez; Álvarez (June 2006). "Lactic acid fermentation of black beans (Phaseolus vulgaris): microbiological and chemical characterization". Journal of the Science of Food and Agriculture 86 (8): 1164–1171. doi:10.1002/jsfa.2490.

[Ridwan-2008-9] Ridwan, BU.; Koning, CJ.; Besselink, MG.; Timmerman, HM.; Brouwer, EC.; Verhoef, J.; Gooszen, HG.; Akkermans, LM. (Jan 2008). "Antimicrobial activity of a multispecies probiotic (Ecologic 641) against pathogens isolated from infected pancreatic necrosis" (PDF). Lett Appl Microbiol 46 (1): 61–7. doi:10.1111/j.1472-765X.2007.02260.x. PMID 17944834.

[pmid21143526-10] Eun, CS.; Kim, YS.; Han, DS.; Choi, JH.; Lee, AR.; Park, YK. (Jan 2011). "Lactobacillus casei prevents impaired barrier function in intestinal epithelial cells". APMIS 119 (1): 49–56. doi:10.1111/j.1600-0463.2010.02691.x. PMID 21143526.

[pmid22132181-11] Zakostelska, Z.; Kverka, M.; Klimesova, K.; Rossmann, P.; Mrazek, J.; Kopecny, J.; Hornova, M.; Srutkova, D.; et al. (2011). "Lysate of probiotic Lactobacillus casei DN-114 001 ameliorates colitis by strengthening the gut barrier function and changing the gut microenvironment". PLOS ONE 6 (11): e27961. doi:10.1371/journal.pone.0027961. PMC 3222668. PMID 22132181.

[12] Kazuyoshi Takeda; Ko Okumura. "Effects of a Fermented Milk Drink Containing Lactobacillus casei Strain Shirota on the Human NK-Cell Activity".

[13] Seesuriyachan P, Takenaka S, Kuntiya A, Klayraung S, Murakami S, Aoki K; Takenaka; Kuntiya; Klayraung; Murakami; Aoki (March 2007). "Metabolism of azo dyes by Lactobacillus casei TISTR 1500 and effects of various factors on decolorization". Water Res. 41 (5): 985–92. doi:10.1016/j.watres.2006.12.001. PMID 17254626.

v t e Dietary supplements

Types	Amino acids Bodybuilding supplement Energy drink Energy bar Fatty acids Herbal Supplements Minerals Prebiotics Probiotics (Lactobacillus Bifidobacterium) Protein bar Vitamins

Vitamins and chemical elements ("minerals")	Retinol (Vitamin A) B vitamins: Thiamine (B₁) Riboflavin (B₂) Niacin (B₃) Pantothenic acid (B₅) Pyridoxine (B₆) Biotin (B₇) Folic acid (B₉) Cyanocobalamin (B₁₂) Ascorbic acid (Vitamin C) Ergocalciferol and Cholecalciferol (Vitamin D) Tocopherol (Vitamin E) Naphthoquinone (Vitamin K) Calcium Choline Chromium Cobalt Copper Fluorine Iodine Iron Magnesium Manganese Molybdenum Phosphorus Potassium Selenium Sodium Sulfur Zinc

Other common ingredients	AAKG β-hydroxy β-methylbutyrate Carnitine Chondroitin sulfate Cod liver oil Copper gluconate Creatine/Creatine supplements Dietary fiber Echinacea Elemental calcium Ephedra Fish oil Folic acid Ginseng Glucosamine Glutamine Grape seed extract Guarana Iron supplements Japanese Honeysuckle Krill oil Lingzhi Linseed oil Lipoic acid Milk thistle Melatonin Red yeast rice Royal jelly Saw palmetto Spirulina St John's wort Taurine Wheatgrass Wolfberry Yohimbine Zinc gluconate

Related articles	Codex Alimentarius Enzyte Hadacol Herbal tea Nutraceutical Multivitamin Nutrition

リンク元	「カゼイ菌」「Lactobacillus casei」
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L. casei