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- 1. ビタミンAの概要 overview of vitamin a
English Journal
- ASP2408 and ASP2409, novel CTLA4-Ig variants with CD86-selective ligand binding activity and improved immunosuppressive potency, created by directed evolution.
- Oshima S1, Karrer EE2, Paidhungat MM3, Neighbors M4, Chapin SJ4, Fan RA4, Reed MA4, Wu K4, Wong C4, Chen Y5, Whitlow M6, Anderson FA3, Bam RA3, Zhang Q3, Larsen BR5, Viswanathan S7, Devens BH4, Bass SH3, Higashi Y8.
- Protein engineering, design & selection : PEDS.Protein Eng Des Sel.2016 May;29(5):159-67. doi: 10.1093/protein/gzw002. Epub 2016 Mar 10.
- The CTLA4-Ig therapeutics abatacept and belatacept inhibit CD28-mediated T cell activation by binding CD80 (B7-1) and CD86 (B7-2) co-stimulatory ligands. Both compounds preferentially bind CD80, yet CD86 has been implicated as the dominant co-stimulatory ligand. Using directed evolution methods, nov
- PMID 26968452
- Gut immunity in a protochordate involves a secreted immunoglobulin-type mediator binding host chitin and bacteria.
- Dishaw LJ1, Leigh B2, Cannon JP1, Liberti A3, Mueller MG1,4, Skapura DP4, Karrer CR1, Pinto MR3, De Santis R3, Litman GW1,4.
- Nature communications.Nat Commun.2016 Feb 15;7:10617. doi: 10.1038/ncomms10617.
- Protochordate variable region-containing chitin-binding proteins (VCBPs) consist of immunoglobulin-type V domains and a chitin-binding domain (CBD). VCBP V domains facilitate phagocytosis of bacteria by granulocytic amoebocytes; the function of the CBD is not understood. Here we show that the gut mu
- PMID 26875669
- Reduced naïve CD8(+) T-cell priming efficacy in elderly adults.
- Briceño O1,2, Lissina A1,2, Wanke K3, Afonso G4,5,6, von Braun A3, Ragon K1,2, Miquel T1,2, Gostick E7, Papagno L1,2, Stiasny K8, Price DA7, Mallone R4,5,6,9, Sauce D1,2, Karrer U3, Appay V1,2.
- Aging cell.Aging Cell.2016 Feb;15(1):14-21. doi: 10.1111/acel.12384. Epub 2015 Oct 15.
- Aging is associated with impaired vaccine efficacy and increased susceptibility to infectious and malignant diseases. CD8(+) T-cells are key players in the immune response against pathogens and tumors. In aged mice, the dwindling naïve CD8(+) T-cell compartment is thought to compromise the inductio
- PMID 26472076
Japanese Journal
- 沖縄舟状海盆から得られた日本初記録のアナゴ科魚類カザリエラアナゴ（新称） <i>Blachea xenobranchialis</i>
- 魚類学雑誌 60(2), 135-140, 2013
- NAID 130005118044
- 天然カロテノイドの分析と構造研究
- オレオサイエンス 12(10), 485-494, 2012
- NAID 130004853404
- Two-Dimensional Electron Gas Recombination in Undoped AlGaN/GaN Heterostructures
- Japanese journal of applied physics. Pt. 1, Regular papers & short notes 43(6A), 3360-3366, 2004-06-15
- NAID 10013154462
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