Jak kinases

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英文文献

  • Inhibition of Janus kinases by tyrosine phosphorylation inhibitor, Tyrphostin AG-490.
  • Rashid S1, Bibi N1, Parveen Z1, Shafique S1.
  • Journal of biomolecular structure & dynamics.J Biomol Struct Dyn.2015 Nov;33(11):2368-79. doi: 10.1080/07391102.2015.1050696. Epub 2015 Jun 23.
  • Janus kinases (JAKs) belong to a crucial family of tyrosine kinases, implicated in the patho-physiology of multiple cancer types, and serve as striking therapeutic targets. To date, many potent, either ATP-competitive (PTK domain) or non-ATP-competitive JAK inhibitors have been identified. Among the
  • PMID 26017266
  • Artocarpus altilis CG-901 alters critical nodes in the JH1-kinase domain of Janus kinase 2 affecting upstream JAK/STAT3 signaling.
  • Nash O1,2,3, Omotuyi O4,5,6, Lee J7, Kwon BM8, Ogbadu L1.
  • Journal of molecular modeling.J Mol Model.2015 Nov;21(11):280. doi: 10.1007/s00894-015-2821-z. Epub 2015 Oct 7.
  • As a key step in achieving low-cost, easily accessible anti-cancer therapy for low- and middle-income countries, we recently established the scientific basis for the folkloric use of Artocarpus altilis for the treatment of cancer by investigating the geranyl dihydrochalcone (CG-901) content and its
  • PMID 26442513

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★リンクテーブル★
関連記事J」「kinase

J」

  [★]

joule

WordNet   license wordnet

「the 10th letter of the Roman alphabet」
j

PrepTutorEJDIC   license prepejdic

「(連続するものの)10番目,第10番のもの」


kinase」

  [★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase

WordNet   license wordnet

「an enzyme that catalyzes the conversion of a proenzyme to an active enzyme」




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