GIST
- Activity of dasatinib, a dual SRC/ABL kinase inhibitor, and IPI-504, a heat shock protein 90 inhibitor, against gastrointestinal stromal tumor-associated PDGFRAD842V mutation.
- Dewaele B, Wasag B, Cools J, Sciot R, Prenen H, Vandenberghe P, Wozniak A, Schoffski P, Marynen P, Debiec-Rychter M.
- Clin Cancer Res. 2008 Sep 15;14(18):5749-58.
- PMID 18794084
WordNet
- the 9th letter of the Roman alphabet (同)i
PrepTutorEJDIC
- 『私は』私が
- iodineの化学記号
- (野球で)innings pitched
UpToDate Contents
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English Journal
- Effects of DLC1 Deficiency on Endothelial Cell Contact Growth Inhibition and Angiosarcoma Progression.
- Sánchez-Martín D1, Otsuka A1, Kabashima K1, Ha T1, Wang D1, Qian X1, Lowy DR1, Tosato G1.
- Journal of the National Cancer Institute.J Natl Cancer Inst.2017 Nov 30. doi: 10.1093/jnci/djx219. [Epub ahead of print]
- PMID 29202196
- Tumor Suppression Efficacy of Heat Shock Protein 90 Inhibitor 17AAG in a Liposarcoma Mouse Model.
- Nam S1,2, Kim H2, Hong D2, Park JB1,2,3, Kim SJ4,2,3.
- Anticancer research.Anticancer Res.2017 Nov;37(11):6291-6302.
- PMID 29061812
- Synergistic anti-tumor effect of 17AAG with the PI3K/mTOR inhibitor NVP-BEZ235 on human melanoma.
- Calero R1, Morchon E2, Martinez-Argudo I3, Serrano R4.
- Cancer letters.Cancer Lett.2017 Oct 10;406:1-11. doi: 10.1016/j.canlet.2017.07.021. Epub 2017 Aug 1.
- PMID 28774796
- In vitro investigation of the effect of matrix molecules on the behavior of colon cancer cells under the effect of geldanamycin derivative.
- Vural K1, Kosova F2, Kurt FÖ3, Tuğlu İ4.
- Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.Tumour Biol.2017 Oct;39(10):1010428317720569. doi: 10.1177/1010428317720569.
- PMID 29034805
Japanese Journal
- HSP90阻害薬の幕開け : 非小細胞肺がんを中心に (抗がん剤治療の最前線 : 分子標的薬剤の使用による進歩(前篇)) -- (新たな標的となる遺伝子とその変異,新薬)
Related Links
- Overview. Retaspimycin hydrochloride (HCl), also known as IPI-504, is an intravenously administered, potent and selective heat shock protein 90 (Hsp90) inhibitor. Cancer cells depend on the Hsp90 chaperone to maintain many proteins ...
- 25 Feb 2010 ... Heat shock protein 90 (Hsp90) is an emerging cancer target. Function of Hsp90. • “Chaperone” protein necessary for stability and function of certain 'client' stability and function of certain client proteins. Function of Hsp90 in ...
- 2010年10月15日 ... Infinity Pharmaceuticals、 Inc. (NASDAQ: INFI) IPI-504 の段階 2 の調査、高度の非 小さいセル肺癌を持つ患者の小説によって IV 管理された Hsp90 シャぺロンの抑制剤 からの結果が、臨床腫瘍学 (NSCLC) (等 Sequist、 J Clin Oncol の ...
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