English Journal

Opposing effects of HIF1α and HIF2α on chromaffin cell phenotypic features and tumor cell proliferation: Insights from MYC-associated factor X.

Qin N1, de Cubas AA, Garcia-Martin R, Richter S, Peitzsch M, Menschikowski M, Lenders JW, Timmers HJ, Mannelli M, Opocher G, Economopoulou M, Siegert G, Chavakis T, Pacak K, Robledo M, Eisenhofer G.
International journal of cancer. Journal international du cancer.Int J Cancer.2014 Nov 1;135(9):2054-64. doi: 10.1002/ijc.28868. Epub 2014 Apr 7.
Pheochromocytomas and paragangliomas (PPGLs) are catecholamine-producing chromaffin cell tumors with diverse phenotypic features reflecting mutations in numerous genes, including MYC-associated factor X (MAX). To explore whether phenotypic differences among PPGLs reflect a MAX-mediated mechanism and
PMID 24676840

Moderate, chronic ethanol feeding exacerbates carbon-tetrachloride-induced hepatic fibrosis via hepatocyte-specific hypoxia inducible factor 1α

Roychowdhury S1, Chiang DJ2, McMullen MR1, Nagy LE3.
Pharmacology research & perspectives.Pharmacol Res Perspect.2014 Oct;2(5):e00061.
The hypoxia-sensing transcriptional factor HIF1α is implicated in a variety of hepato-pathological conditions; however, the contribution of hepatocyte-derived HIF1α during progression of alcoholic liver injury is still controversial. HIF1α induces a variety of genes including those involved in ap
PMID 25089199

Correlation between biological marker expression and fluorine-18 fluorodeoxyglucose uptake in hepatocellular carcinoma.

Mano Y1, Aishima S2, Kubo Y2, Tanaka Y2, Motomura T3, Toshima T3, Shirabe K3, Baba S4, Maehara Y3, Oda Y5.
American journal of clinical pathology.Am J Clin Pathol.2014 Sep;142(3):391-7. doi: 10.1309/AJCPG8AFJ5NRKLLM.
OBJECTIVES: This study investigated the association between several biological markers and fluorine-18 fluorodeoxyglucose (FDG) uptake in patients with hepatocellular carcinoma.METHODS: Forty-two patients with hepatocellular carcinoma who underwent FDG positron emission tomography were included in t
PMID 25125631