WordNet

the 8th letter of the Roman alphabet (同)h
any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)

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1. 赤血球抗原および抗体のプライマー a primer of red blood cell antigens and antibodies
2. 抗原提示細胞 antigen presenting cells
3. 胎児および新生児における免疫細胞の発達 the development of immune cells in the fetus and neonate
4. 前立腺癌のスクリーニング screening for prostate cancer
5. 妊娠中の微量な赤血球抗体の意義 significance of minor red blood cell antibodies during pregnancy

PEP-1-SIRT2 inhibits inflammatory response and oxidative stress-induced cell death via expression of antioxidant enzymes in murine macrophages.

Kim MJ, Kim DW, Park JH, Kim SJ, Lee CH, Yong JI, Ryu EJ, Cho SB, Yeo HJ, Hyeon J, Cho SW, Kim DS, Son O, Park J, Han KH, Cho YS, Eum WS, Choi SY.SourceDepartment of Biomedical Science and Research Institute of Bioscience and Biotechnology, Hallym University, Chunchon 200-702, Korea.
Free radical biology & medicine.Free Radic Biol Med.2013 Oct;63:432-45. doi: 10.1016/j.freeradbiomed.2013.06.005. Epub 2013 Jun 12.
Sirtuin 2 (SIRT2), a member of the sirtuin family of proteins, plays an important role in cell survival. However, the biological function of SIRT2 protein is unclear with respect to inflammation and oxidative stress. In this study, we examined the protective effects of SIRT2 on inflammation and oxid
PMID 23770196

Siracusa MC, Kim BS, Spergel JM, Artis D.SourceDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.
The Journal of allergy and clinical immunology.J Allergy Clin Immunol.2013 Oct;132(4):789-801; quiz 788. doi: 10.1016/j.jaci.2013.07.046.
Basophils were discovered by Paul Ehrlich in 1879 and represent the least abundant granulocyte population in mammals. The relative rarity of basophils and their phenotypic similarities with mast cells resulted in this cell lineage being historically overlooked, both clinically and experimentally. Ho
PMID 24075190

IL-2-inducible T-cell kinase modulates TH2-mediated allergic airway inflammation by suppressing IFN-γ in naive CD4+ T cells.

Kannan AK, Sahu N, Mohanan S, Mohinta S, August A.SourceDepartment of Microbiology and Immunology, Cornell University, Ithaca, NY.
The Journal of allergy and clinical immunology.J Allergy Clin Immunol.2013 Oct;132(4):811-20.e1-5. doi: 10.1016/j.jaci.2013.04.033. Epub 2013 Jun 12.
BACKGROUND: Asthma is a predominantly TH2 cell-dominated inflammatory disease characterized by airway inflammation and a major public health concern affecting millions of persons. The Tec family tyrosine kinase IL-2-inducible T-cell kinase (Itk) is primarily expressed in T cells and critical for the
PMID 23768572

Superoxide stimulation enhances CXCR4 expression in heart muscle-derived stem cells via ASK1 activation

Akashi Shintaro,Miura Toshiro,Shibuya Masaki,Fukagawa Yasuhiro,Oda Takamasa,Nakamura Takeshi,Ikeda Yasuhiro,Matsuzaki Masunori,Yano Masafumi
The bulletin of the Yamaguchi Medical School 60(1-2), 11-18, 2013
… Methods and Results: Heart muscle-derived Sca-1(+) cells (HDSCs) were isolated from normal mouse heart using surface antigen Sca-1. … The expression of CXCR4 was enhanced by stimulation of hydrogen peroxide (0.1, 0.33, 1μM) for 24h. … H_2O_2 stimulation enhanced ASK1 p966 phosphory- lation. …
NAID 120005373259

Chemokine-dependent T cell migration requires aquaporin-3-mediated hydrogen peroxide uptake.

Hara-Chikuma Mariko,Chikuma Shunsuke,Sugiyama Yoshinori,Kabashima Kenji,Verkman Alan S,Inoue Shintaro,Miyachi Yoshiki
The Journal of experimental medicine 209(10), 1743-1752, 2012-09-24
… Chemokine-dependent trafficking is indispensable for the effector function of antigen-experienced T cells during immune responses. … T cell migration toward chemokines is dependent on AQP3-mediated hydrogen peroxide (H(2)O(2)) uptake but not the canonical water/glycerol transport. …
NAID 120005054804

Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling.

Nakajima Saeko,Igyártó Botond Z,Honda Tetsuya,Egawa Gyohei,Otsuka Atsushi,Hara-Chikuma Mariko,Watanabe Norihiko,Ziegler Steven F,Tomura Michio,Inaba Kayo,Miyachi Yoshiki,Kaplan Daniel H,Kabashima Kenji
The Journal of allergy and clinical immunology 129(4), 1048-1055.e6, 2012-04
… Consistently, even in the steady state, permanent LC depletion resulted in decreased serum IgE levels, suggesting that LCs mediate the T[H]2 local environment. … Conclusion: LCs initiate epicutaneous sensitization with protein antigens and induce T[H]2-type immune responses via TSLP signaling. …
NAID 120004025593