WordNet
- the 7th letter of the Roman alphabet (同)g
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- 1. 白血球粘着不全症 leukocyte adhesion deficiency
- 2. 炎症の病因における白血球内皮細胞接着 leukocyte endothelial adhesion in the pathogenesis of inflammation
- 3. マンノース結合レクチン mannose binding lectin
- 4. 血液-血液透析膜の相互作用に関与する生化学的機序 biochemical mechanisms involved in blood hemodialysis membrane interactions
- 5. コレラ菌感染の病因 pathogenesis of vibrio cholerae infection
English Journal
- N-Glycosylations of human α1,3-fucosyltransferase IX are required for full enzyme activity.
- Seelhorst K, Stacke C, Ziegelmüller P, Hahn U.SourceHamburg University, MIN-Faculty, Department of Chemistry, Institute of Biochemistry and Molecular Biology, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany.
- Glycobiology.Glycobiology.2012 Dec 21. [Epub ahead of print]
- Human α1,3-fucosyltransferase IX catalyzes the transfer of L-fucose from GDP-β-L-Fucose to N-acetyllactosamine, generating a Lewis X epitope, and is thereby involved in the synthesis of fucosylated cell surface glycoconjugates. It contains three putative N-glycosylation sites (Asn62, Asn101 and As
- PMID 23263199
- Donor substrate binding and enzymatic mechanism of human core α1,6-fucosyltransferase (FUT8).
- Kötzler MP, Blank S, Bantleon FI, Spillner E, Meyer B.SourceInstitute of Organic Chemistry, University of Hamburg, Germany.
- Biochimica et biophysica acta.Biochim Biophys Acta.2012 Dec;1820(12):1915-25. doi: 10.1016/j.bbagen.2012.08.018. Epub 2012 Sep 7.
- BACKGROUND: Fucosylation is essential for various biological processes including tumorigenesis, inflammation, cell-cell recognition and host-pathogen interactions. Biosynthesis of fucosylated glycans is accomplished by fucosyltransferases. The enzymatic product of core α1,6-fucosyltransferase (FUT8
- PMID 22982178
Japanese Journal
- Decrease in Antithrombin III Fucosylation by Expressing GDP-fucose Transporter siRNA in Chinese Hamster Ovary Cells(CELL AND TISSUE ENGINEERING)
- Omasa Takeshi,Tanaka Ryo,Doi Tomohiro,Ando Masayuki,Kitamoto Yuka,Honda Kohsuke,Kishimoto Michimasa,Ohtake Hisao
- Journal of bioscience and bioengineering 106(2), 168-173, 2008-08-25
- … The full-length cDNA of GDP-fucose transporter (GFT) was cloned from Chinese hamster ovary (CHO) 13D-35D cells. … CHO cells, which were transfected with the siRNA expression plasmid, showed approximately 75% reduction of Golgi-GDP fucose, resulting in 10-40% increase in defucosylated AT-III. …
- NAID 110006873806
- Biological Function of Fucosylation in Cancer Biology
- MIYOSHI Eiji,MORIWAKI Kenta,NAKAGAWA Tsutomu
- The journal of biochemistry 143(6), 725-729, 2008-06-01
- NAID 10024910144
Related Links
- L-フコシドは生体内では、糖ヌクレオチドの一種GDP-フコースから、各種フコース転移 酵素による反応によってつくられる。ヒトでは上記H抗原のほかいくつかフコース転移 酵素がクローニングされている。植物ではキシログルカンのフコース転移酵素が初めに ...
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| リンク元 | 「グアノシン二リン酸フコース」「GDPフコース」 |
| 関連記事 | 「GDP」「G」 |
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