Gタンパク質αサブユニット
WordNet
- first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
- the 1st letter of the Greek alphabet
- the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
- early testing stage of a software or hardware product; "alpha version"
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- a unit of force equal to the force exerted by gravity; used to indicate the force to which a body is subjected when it is accelerated (同)gee, g-force
- the 7th letter of the Roman alphabet (同)g
- any high mountain
PrepTutorEJDIC
- アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)
- 蛋白(たんばく)質
- 高山,高峰
UpToDate Contents
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- 1. ペプチドホルモンのシグナル伝達および調節 peptide hormone signal transduction and regulation
- 2. 幼児および小児における低カルシウム血症の病因 etiology of hypocalcemia in infants and children
- 3. 小児における先天性および後天性の甲状腺腫 congenital and acquired goiter in children
- 4. 新生児グレーヴス病の評価およびマネージメント evaluation and management of neonatal graves disease
- 5. 原発性早期卵巣障害（早期卵巣機能不全）の病因と原因 pathogenesis and causes of spontaneous primary ovarian insufficiency premature ovarian failure
English Journal
- Development of the mammalian axial skeleton requires signaling through the Gαi subfamily of heterotrimeric G proteins.
- Plummer NW, Spicher K, Malphurs J, Akiyama H, Abramowitz J, Nürnberg B, Birnbaumer L.SourceLaboratory of Neurobiology, National Institute of Environmental Health Sciences, National Institutes of Health/Department of Health and Human Services, Durham, NC 27709.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2012 Dec 26;109(52):21366-71. doi: 10.1073/pnas.1219810110. Epub 2012 Dec 11.
- 129/SvEv mice with a loss-of-function mutation in the heterotrimeric G protein α-subunit gene Gnai3 have fusions of ribs and lumbar vertebrae, indicating a requirement for Gα(i) (the "inhibitory" class of α-subunits) in somite derivatives. Mice with mutations of Gnai1 or Gnai2 have neither defect
- PMID 23236180
- Structural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis.
- Bosch DE, Kimple AJ, Manning AJ, Muller RE, Willard FS, Machius M, Rogers SL, Siderovski DP.SourceDepartment of Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
- Structure (London, England : 1993).Structure.2012 Dec 19. pii: S0969-2126(12)00427-3. doi: 10.1016/j.str.2012.11.012. [Epub ahead of print]
- G protein signaling pathways, as key components of physiologic responsiveness and timing, are frequent targets for pharmacologic intervention. Here, we identify an effector for heterotrimeric G protein α subunit (EhGα1) signaling from Entamoeba histolytica, the causative agent of amoebic colitis.
- PMID 23260656
- An improved bioluminescence-based signaling assay for odor sensing with a yeast expressing a chimeric olfactory receptor.
- Fukutani Y, Ishii J, Noguchi K, Kondo A, Yohda M.SourceDepartment of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan.
- Biotechnology and bioengineering.Biotechnol Bioeng.2012 Dec;109(12):3143-51. doi: 10.1002/bit.24589. Epub 2012 Jul 4.
- The goal of this work was to improve the bioluminescence-based signaling assay system to create a practical application of a biomimetic odor sensor using an engineered yeast-expressing olfactory receptors (ORs). Using the yeast endogenous pheromone receptor (Ste2p) as a model GPCR, we determined the
- PMID 22729937
Japanese Journal
- Aggregatibacter Actinomycetemcomitans reduced GNAS Gene Expression in Human Trophoblasts
- Li Ying
- Journal of Hard Tissue Biology 22(1), 35-40, 2013
- … In BeWo cells, Aa-LPS altered many gene expressions including the alpha subunit of the heterotrimeric G protein that stimulates adenylyl cyclase (GNAS) mRNA level. …
- NAID 130004848408
- The White-Rot Fungus Pleurotus ostreatus Transformant Overproduced Intracellular cAMP and Laccase
- YAO Yuki,SAKAMOTO Takaiku,HONDA Yoichi [他],KAGOTANI Yasuyuki,IZUMITSU Kousuke,SUZUKI Kazumi,IRIE Toshikazu
- Bioscience, Biotechnology, and Biochemistry 77(11), 2309-2311, 2013
- … Transformation of Pleurotus ostreatus PC9 with the mutated heterotrimeric G protein alpha subunit (Gα) gene resulted in higher laccase (Lac) activity and intracellular cyclic adenosine monophosphate (cAMP) concentrations as compared to those in wild-type PC9. …
- NAID 130003381926
- 2K1412 活性化後に起こるGα2とcAMP受容体間相互作用の検証(細胞生物的課題2,第49回日本生物物理学会年会)
- Morimatsu Miki,Miyanaga Yukihiro,Tanabe Kaori,Ueda Masahiro
- 生物物理 51(SUPPLEMENT_1), S92-S93, 2011-08-15
- NAID 110008903306
Related Links
- Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with ...
- InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable ...
Related Pictures
★リンクテーブル★
| リンク元 | 「G-alpha」「GTP-binding protein alpha subunit」 |
| 関連記事 | 「G」「alpha」「G protein」「Gd」「g」 |
「G-alpha」
「GTP-binding protein alpha subunit」
「G」
「alpha」
- 関
- alfa
「G protein」
「Gd」
「g」
- 関
- gram