フォルスマン抗原、Forssman抗原
WordNet
- any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)
PrepTutorEJDIC
- 抗原(生物の体内にはいって免疫体を作る物質)
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/01/20 17:00:28」(JST)
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The Forssman Antigen is a glycolipid heterophil protein and a type of heterogenetic antigen found in certain animals like dogs, horses, cats, turtles and sheep, including enteric organisms such as pneumococci. In sheep, it is found in their erythrocytes but not on tissue and organs, except for hamsters and guinea pigs. The Forssman antigen is distinct from the Paul-Bunnell antigen, antibodies to which are diagnostic of glandular fever (infectious mononucleosis). Both antigens are present on the red blood cells of horse and sheep but guinea pig kidney cells have only the Forssman antigen. A serum positive for glandular fever therefore agglutinates horse or sheep red blood cells after absorption with guinea pig kidney (see Basson V, Sharp AA (May 1969). "Monospot: a differential slide test for infectious mononucleosis". J. Clin. Pathol. 22 (3): 324–5. doi:10.1136/jcp.22.3.324. PMC 474075. PMID 5814738.)
Namesake
It is named for John Frederick Forssman (1868 – 1947), a pioneer Swedish Pathologist, who described it in 1930.
References
- "Forssman Antigen -- Medical Definition". medilexicon.com. Retrieved 2014-06-12.
- "Forssman antigen - definition of Forssman antigen in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.". medical-dictionary.thefreedictionary.com. Retrieved 2014-06-12.
- "Forssman antigen - Definition and More from the Free Merriam-Webster Dictionary". merriam-webster.com. Retrieved 2014-06-12.
- "Whonamedit - Arvid Vilhelm Lindau". whonamedit.com. Retrieved 2014-06-12.
UpToDate Contents
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English Journal
- Crystal structure of a symbiosis-related lectin from octocoral.
- Kita A1, Jimbo M2, Sakai R3, Morimoto Y4, Miki K5.
- Glycobiology.Glycobiology.2015 Sep;25(9):1016-23. doi: 10.1093/glycob/cwv033. Epub 2015 May 28.
- D-Galactose-binding lectin from the octocoral, Sinularia lochmodes (SLL-2), distributes densely on the cell surface of microalgae, Symbiodinium sp., an endosymbiotic dinoflagellate of the coral, and is also shown to be a chemical cue that transforms dinoflagellate into a non-motile (coccoid) symbiot
- PMID 26022515
- Monoclonal anti-A activity against the FORS1 (Forssman) antigen.
- Barr K1, Korchagina E, Popova I, Bovin N, Henry S.
- Transfusion.Transfusion.2015 Jan;55(1):129-36. doi: 10.1111/trf.12773. Epub 2014 Jul 14.
- BACKGROUND: The FORS blood group system (originally recognized as the Apae phenotype) was discovered by sporadic activity against polyclonal anti-A reagents and activity against the lectin Helix pomatia. The extent of monoclonal anti-A reagent activity against the FORS1 antigen is serologically and
- PMID 25039359
- Expression of GBGT1 is epigenetically regulated by DNA methylation in ovarian cancer cells.
- Jacob F1, Hitchins MP, Fedier A, Brennan K, Nixdorf S, Hacker NF, Ward R, Heinzelmann-Schwarz VA.
- BMC molecular biology.BMC Mol Biol.2014 Oct 7;15:24. doi: 10.1186/1471-2199-15-24.
- BACKGROUND: The GBGT1 gene encodes the globoside alpha-1,3-N-acetylgalactosaminyltransferase 1. This enzyme catalyzes the last step in the multi-step biosynthesis of the Forssman (Fs) antigen, a pentaglycosyl ceramide of the globo series glycosphingolipids. While differential GBGT1 mRNA expression h
- PMID 25294702
Japanese Journal
- Crystal structure of a symbiosis-related lectin from octocoral.
- Effects of Sho-seiryu-to (Xiao-Qing-Long-Tang) on experimental allergic reactions :
- TRENDS IN GLYCOSPHINGOLIPIDS CHANGE DURING GROWTH AND DIFFERENTIATION OF RAT RENAL GLOMERULAR EPITHELIAL CELLS, SGE1, IN VITRO
Related Links
- antigen [an´tĭ-jen] any substance capable, under appropriate conditions, of inducing a specific immune response and reacting with the products of that response; that is, with specific antibody or specifically sensitized T lymphocytes, or both.
- Define Forssman antigen: also an·ti·gene n. A substance that when introduced into the body stimulates the production of an antibody. Antigens include toxins, bacteria, foreign blood... Forssman antigen - definition of Forssman ...
★リンクテーブル★
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- 英
- Forssman antigen, Forssman's antigen
- 同
- Forssman抗原、異種抗原 heteroantigen、ヘテロフィル抗原、異好抗原 heterophile antigen
- 関
- フォルスマン抗体