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1. 成人における門脈圧亢進症 portal hypertension in adults
2. 非肝硬変性門脈圧亢進症 noncirrhotic portal hypertension
3. 肝硬変患者における静脈瘤出血の予測 prediction of variceal hemorrhage in patients with cirrhosis
4. 造血細胞移植後の肝類洞閉塞症候群（静脈閉塞性疾患）の診断 diagnosis of hepatic sinusoidal obstruction syndrome veno occlusive disease following hematopoietic cell transplantation
5. 肝硬変患者における静脈瘤出血に対する一次予防および静脈瘤形成予防 primary and pre primary prophylaxis against variceal hemorrhage in patients with cirrhosis

English Journal

Comparative randomized study on efficacy of losartan versus propranolol in lowering portal pressure in decompensated chronic liver disease.

Agasti AK1, Mahajan AU, Phadke AY, Nathani PJ, Sawant P.
Journal of digestive diseases.J Dig Dis.2013 May;14(5):266-71. doi: 10.1111/1751-2980.12025.
OBJECTIVE: This study aimed to compare the efficacy of losartan, an angiotensin II receptor antagonist, with propranolol on portal hypertension in patients with decompensated chronic liver disease.METHODS: In all, 30 patients with Child-Pugh B cirrhosis and large varices without any prior therapy fo
PMID 23280243

Hepato-systemic gradient of carbon monoxide in cirrhosis.

Tarquini R1, Masini E, La Villa G, Mazzoccoli G, Mastroianni R, Romanelli RG, Vizzutti F, Arena U, Santosuosso U, Laffi G.
European journal of internal medicine.Eur J Intern Med.2012 Jan;23(1):e14-8. doi: 10.1016/j.ejim.2011.10.008. Epub 2011 Nov 21.
BACKGROUND AND AIMS: Experimental data suggest that in liver cirrhosis splanchnic and systemic vasculature exhibit marked endothelial Carbon monoxide (CO) overproduction, while recent data demonstrated heme oxygenase (HO) hyperactivity in the liver of rats with cirrhosis. No data are so far availabl
PMID 22153542

Should we routinely measure portal pressure in patients with cirrhosis, using hepatic venous pressure gradient (HVPG) as a guide for prophylaxis and therapy of bleeding and rebleeding? No.

Thalheimer U1, Bellis L, Puoti C, Burroughs AK.
European journal of internal medicine.Eur J Intern Med.2011 Feb;22(1):5-7. doi: 10.1016/j.ejim.2010.12.006. Epub 2010 Dec 31.
Portal hypertension (PH) is a severe complication of liver cirrhosis. Measurement of the degree of portal hypertension is usually performed by measuring the hepatic venous pressure gradient (HVPG) which is the difference between the free hepatic venous pressure (FHVP) and the wedged hepatic venous p
PMID 21238884

Japanese Journal

無腹水肝硬変患者の肝及び全身循環動態に及ぼす spironolactone の作用

奥村英正,古明地弘和,荒牧琢己,里村克章,勝田悌実,寺田秀人,関山達也,大須賀勝,小宮山徹三,赤池正博
肝臓 29(12), 1593-1598, 1988
… The measurements of hemodynamics were performed prior and after the oral administration of spironolactone at daily doses of 100mg for four weeks.<BR>The hepatic venous pressure gradient (as WHVP-FHVP) significantly decreased by 24.7%. …
NAID 130000879139

慢性肝疾患の門脈圧に対するpropranololの効果 : vasopressin との比較

奥村英正,関山達也,勝田悌実,荒牧琢己,里村克章,赤池正博,寺田秀人,関野三津也
肝臓 25(12), 1534-1540, 1984
… After intravenous infusion of 5mg of propranolol for 10 minutes, wedged and free hepatic venous presure (WHVP, FHVP), estimated hepatic blood flow (EHBF), cardiac output and total systemic vascular resistance (TSR) were measured serially. … Portal venous pressure (WHVP-FHVP) decreased significantly by 23% at 20 minutes after the start of infusion and the effect persisted for 50 minutes. …
NAID 130000874634

Related Pictures

HVPG (WHVP-FHVP) >12mmHg Images - Frompo FHVP - Free Hepatic Venous Pressure HVPG=WHVP-FHVP 关系/示意图/经颈 Hypertension: HVPG (WHVP-FHVP) >12mmHg FHVP Financial Policy hvpg 为 whvp 减去 fhvp hvpg whvp fhvp figure 3 fhvp free hepatic vein pressure