有効腎血漿流量有効腎血循環量 effective renal plasma flow

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/16 08:35:55」(JST)

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Parameter	Value
renal blood flow	RBF=1000 ml/min
hematocrit	HCT=40%
renal plasma flow	RPF=600 ml/min
filtration fraction	FF=20%
glomerular filtration rate	GFR=120 ml/min
urine flow rate	V=1 mL/min

Sodium	Inulin	Creatinine	PAH
S_Na=150 mEq/L	S_In=1 mg/mL	S_Cr=0.01 mg/ml	S_PAH=
U_Na=710 mEq/L	U_In=150 mg/mL	U_Cr=1.25 mg/mL	U_PAH=
C_Na=5 mL/min	C_In=150 ml/min	C_Cr=125 mL/min	C_PAH=420 ml/min
			ER=90%
			ERPF=540 ml/min

Effective renal plasma flow (eRPF) is a measure used in renal physiology^[1] to calculate renal plasma flow (RPF) and hence estimate renal function.

Where extraction ratio is the ratio of compound entering the kidney that got excreted into the final urine.

When using a compound with an extraction ratio near 1, such as para-aminohippurate (PAH), then eRPF is almost equal to RPF. Therefore, PAH clearance is a method to estimate renal plasma flow.

References

^ "Hubio562: Clearance Lab Answers". http://courses.washington.edu/hubio562/clearanceLab/clearancelabAnswers.html. Retrieved 2009-04-29.^{[dead link]}

English Journal

Long-term functional evaluation of the treated kidney in a prospective series of patients who underwent laparoscopic partial nephrectomy for small renal tumors.

Porpiglia F, Fiori C, Bertolo R, Morra I, Russo R, Piccoli G, Angusti T, Podio V.SourceDivision of Urology, University of Turin, "San Luigi Gonzaga" Hospital, Orbassano, Turin, Italy.
European urology.Eur Urol.2012 Jul;62(1):130-5. Epub 2012 Feb 14.
BACKGROUND: Renal scintigraphy may allow long-term monitoring of ischemic damage after partial nephrectomy (PN).OBJECTIVE: Evaluate use of renal scintigraphy for evaluating long-term effects of warm ischemia on renal function in patients with a normal contralateral kidney.DESIGN, SETTING, AND PARTIC
PMID 22349568

Renal function and adaptive changes in patients after radical or partial nephrectomy.

Antoniewicz AA, Poletajew S, Borówka A, Pasierski T, Rostek M, Pikto-Pietkiewicz W.SourceDepartment of Urology, Medical Centre of Postgraduate Education, 2 Bursztynowa St, 04749, Warsaw, Poland.
International urology and nephrology.Int Urol Nephrol.2012 Jun;44(3):745-51. Epub 2011 Sep 21.
INTRODUCTION: Renal function after renal surgery depends on the volume of renal parenchyma loss and improves in the postoperative period. However, the knowledge on kidney function after radical (RN) and partial (PN) nephrectomy is still insufficient. The aim of this study is to analyze the global re
PMID 21947980

Japanese Journal

臨床研究・症例報告先天性腎性低尿酸血症患児におけるMAG3%uptake値は真の有効腎血漿流量(ERPF)を反映しているか

松山健,長秀男,山本敬一 [他]
小児科臨床 63(7), 1629-1633, 2010-07
NAID 40017155915

海外論文紹介 : Renal Function in Glycogen Storage Disease Type I, Natural Course, and Renopreservative Effects of ACE Inhibition

中島滋郎
日本小児腎臓病学会雑誌 23(1), 58-59, 2010
… GERはI125イソタラム酸で, ERPFはI131馬尿酸で測定し, 体表面積で補正した。 … 【結果】GERとERPFは年齢に対して二相性の変化を示した。 … 【結論】今回の検討では, I型糖原病患者はGERとERPFは二相性の変化を示し, その後, 微量アルブミン尿および蛋白尿を呈する経過を示した。 …
NAID 130000422950