EGR transcription factor

初期増殖応答転写因子

関

early growth response transcription factor

WordNet

1. be a contributing factor; "make things factor into a companys profitability"
2. any of the numbers (or symbols) that form a product when multiplied together
3. an independent variable in statistics
4. anything that contributes causally to a result; "a number of factors determined the outcome"
5. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
6. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
7. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
8. a concept whose truth can be proved; "scientific hypotheses are not facts"
9. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
10. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
11. (genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA
12. a sound or television recording (e.g., from a broadcast to a tape recording)
13. something written, especially copied from one medium to another, as a typewritten version of dictation (同)written text
14. the 5th letter of the Roman alphabet (同)e

PrepTutorEJDIC

1. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
2. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
3. 〈U〉(…を)書き写す(書き直す)こと,(…の)転写,謄写《+of+名》 / 〈C〉写し(書き直し)[たもの] / 〈U〉〈C〉編曲[されたもの] / 〈U〉〈C〉(ラジオ・テレビの)録音(録画)

UpToDate Contents

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English Journal

• Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation.

• Kwon O, Soung NK, Thimmegowda NR, Jeong SJ, Jang JH, Moon DO, Chung JK, Lee KS, Kwon YT, Erikson RL, Ahn JS, Kim BY.SourceKorea Research Institute of Bioscience and Biotechnology (KRIBB), 685-2, Ochang-eup, Cheongwon-gun, 363-883, Republic of Korea.
• Cellular signalling.Cell Signal.2012 Apr;24(4):943-50. Epub 2011 Dec 30.
• Patulin is a fungal mycotoxin of Aspergilus and Penicillium that is commonly found in rotting fruits and exerts its potential toxic effect mainly by reactive oxygen species (ROS) generation. However, the effect of patulin on cancer cells as well as its intracellular mechanism has been controversial
• PMID 22230687

• PKCδ-dependent activation of ERK1/2 leads to upregulation of the human NHE2 transcriptional activity in intestinal epithelial cell line C2BBe1.

• Muthusamy S, Shukla S, Amin MR, Cheng M, Orenuga T, Dudeja PK, Malakooti J.SourceDept. of Medicine, Univ. of Illinois at Chicago, Chicago, IL 60612. malakoot@uic.edu.
• American journal of physiology. Gastrointestinal and liver physiology.Am J Physiol Gastrointest Liver Physiol.2012 Feb;302(3):G317-25. Epub 2011 Nov 3.
• The apical Na(+)/H(+) exchanger (NHE) isoform NHE2 is involved in transepithelial Na(+) absorption in the intestine. Our earlier studies have shown that mitogenic agent phorbol 12-myristate 13-acetate (PMA) induces the expression of NHE2 through activation of transcription factor early growth respon
• PMID 22052014

• The Nucleosome Remodeling and Deacetylase Chromatin Remodeling (NuRD) Complex Is Required for Peripheral Nerve Myelination.

• Hung H, Kohnken R, Svaren J.SourceCellular and Molecular Pathology Graduate Program, Department of Comparative Biosciences, Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin 53705.
• The Journal of neuroscience : the official journal of the Society for Neuroscience.J Neurosci.2012 Feb 1;32(5):1517-27.
• Several key transcription factors and coregulators important to peripheral nerve myelination have been identified, but the contributions of specific chromatin remodeling complexes to peripheral nerve myelination have not been analyzed. Chromodomain helicase DNA-binding protein 4 (Chd4) is the core c
• PMID 22302795

Japanese Journal

• Transcription factor-recognition sequences potentially involved in modulation of gene expression after exposure to low-dose-rate γ-rays in the mouse liver

• VARES Guillaume,UEHARA Yoshihiko,ONO Tetsuya,NAKAJIMA Tetsuo,WANG Bing,TAKI Keiko,MATSUMOTO Tsuneya,OGHISO Yoichi,TANAKA Kimio,ICHINOHE Kazuaki,NAKAMURA Shingo,TANAKA Satoshi,NENOI Mitsuru
• Journal of radiation research 52(2), 249-256, 2011-03-16
• … Nucleotide sequences in the neighboring region of the up-regulated, down-regulated, and unaffected genes were retrieved from the Entrez Gene database, and recognition sequences for transcription factors (TFs) were searched using the TFSEARCH database. …
• NAID 10027956910

• The transcriptional cofactor Nab2 is induced by TGF-β and suppresses fibroblast activation: Physiological roles and impaired expression in scleroderma

• Bhattacharyya Swati,Wei Jun,Melichian Denisa S.,Milbrandt Jeffrey,Takehara Kazuhiko,Varga John
• PLoS ONE 4(10), 7620, 2009
• … By stimulating collagen synthesis and myofibroblasts differentiation, transforming growth factor-β (TGF-β) plays a pivotal role in tissue repair and fibrosis. … The early growth response-1 (Egr-1) transcription factor mediates profibrotic TGF-β responses, and its expression is elevated in biopsies from patients with scleroderma. …
• NAID 120002314575

• Reduction of Early Growth Response-1 Gene Expression in Osteoblasts by Hydrogen Peroxide

• Yang Chia-Hua,Li Ying,Chang Wei-Jen,Wang Duen-Jeng,Lee Sheng-Yang,Abiko Yoshimitsu
• Journal of hard tissue biology 17(1), 31-34, 2008-04
• … The zinc finger transcription factor, Early Growth Response-1 (Egr-1) is a potential regulator as a transcription factor of many target genes, and plays a role in cell growth, development, and differentiation. … However, the effect of ageing on Egr-1 gene expression has not yet been ascertained. …
• NAID 110006791913

Related Links

• The transcription factor Egr1 is a direct regulator of multiple ...

PTEN The tumor suppressor gene, PTEN/MMAC1/TEP1, is a proapoptotic factor that is frequently suppressed or mutated in a variety of human cancers (reviewed in ref. 19). Egr1 is one of the first transcription factors ...

• Transcription factor Egr-1 supports FGF-dependent ...

Article Nature Medicine 9, 1026 - 1032 (2003) Published online: 20 July 2003; | doi:10.1038/nm905 Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth Roger G ...

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★リンクテーブル★

リンク元	「初期増殖応答転写因子」「early growth response transcription factor」
関連記事	「fact」「factor」「transcription factor」「EG」「EGR」

「初期増殖応答転写因子」

　　[★]

英

early growth response transcription factor、EGR transcription factor

「early growth response transcription factor」

　　[★]

初期増殖応答転写因子

関

EGR transcription factor

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「transcription factor」

　　[★]

• 転写制御因子、転写因子

関

TF、transcriptional regulator、transcriptional regulatory element

「EG」

　　[★] 好酸球性肉芽腫症 eosinophilic granuloma

「EGR」

　　[★]

同

erythrocyte glutatuione reductase