Duchenne's muscular dystrophy

出典: meddic

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「the most common form of muscular dystrophy; inheritance is X-linked recessive (carried by females but affecting only males)」
pseudohypertrophic dystrophy

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/11/17 00:54:19」(JST)

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  • A prostaglandin D2 metabolite is elevated in the urine of Duchenne muscular dystrophy patients and increases further from 8years old.
  • Nakagawa T, Takeuchi A, Kakiuchi R, Lee T, Yagi M, Awano H, Iijima K, Takeshima Y, Urade Y, Matsuo M.SourceDepartment of Pediatrics, Graduate School of Medicine, Kobe University, Chuo, Kobe 6500017, Japan.
  • Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2013 Aug 23;423:10-4. doi: 10.1016/j.cca.2013.03.031. Epub 2013 Apr 19.
  • BACKGROUND: Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disease caused by muscle dystrophin deficiency. Downstream of the primary dystrophin deficiency is not well elucidated. Here, the hypothesis that prostaglandin D2 (PGD2)-mediated inflammation is involved in the pathology o
  • PMID 23603101
  • Molecular analysis of the dystrophin gene in 407 Chinese patients with Duchenne/Becker muscular dystrophy by the combination of multiplex ligation-dependent probe amplification and Sanger sequencing.
  • Chen WJ, Lin QF, Zhang QJ, He J, Liu XY, Lin MT, Murong SX, Liou CW, Wang N.SourceDepartment of Neurology and Institute of Neurology, First Affiliated Hospital, Fujian Medical University, Fuzhou, Fujian, China; Center of Neuroscience, Fujian Medical University Fuzhou, Fujian, China. Electronic address: wanjinchen75@yahoo.com.cn.
  • Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.2013 Aug 23;423:35-8. doi: 10.1016/j.cca.2013.04.006. Epub 2013 Apr 13.
  • BACKGROUND: Progressive muscular dystrophy is a leading neuromuscular disorder without any effective treatments and a common genetic cause of mortality among teenagers. A challenge exists in the screening of subtle mutations in 79 exons and little is known about the genotype-phenotype correlation.ME
  • PMID 23588064
  • Inhibition of iPLA2 β and of stretch-activated channels by doxorubicin alters dystrophic muscle function.
  • Ismail HM, Dorchies OM, Perozzo R, Strosova MK, Scapozza L, Ruegg UT.SourcePharmacology, Geneva-Lausanne School of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Geneva, Switzerland; Pharmaceutical Biochemistry, Geneva-Lausanne School of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Geneva, Switzerland.
  • British journal of pharmacology.Br J Pharmacol.2013 Aug;169(7):1537-50. doi: 10.1111/bph.12188.
  • BACKGROUND AND PURPOSE: Chronic elevation in intracellular Ca(2+) concentration participates in death of skeletal muscle from mdx mice, a model for Duchenne muscular dystrophy (DMD). Candidate pathways mediating this Ca(2+) overload involve store-operated channels (SOCs) and stretch-activated channe
  • PMID 23849042


  • 心筋ストレイン分布の評価による Duchenne 型筋ジストロフィーの早期心筋病変の検出について
  • 山本 哲志,川合 宏哉,大西 哲存,林 伸英,木下 承晧,河野 誠司,平田 健一,松尾 雅文,熊谷 俊一
  • Japanese journal of medical ultrasonics = 超音波医学 35, S322, 2008-04-15
  • NAID 10023914871
  • 進行性筋ジストロフィーの心エコー所見 : どの指標が心臓合併症の早期発見に有用か?
  • 森 一博,松岡 優,多田羅 勝義,宮崎 達志,早淵 康信,井上 美紀,香美 祥二,大西 達也
  • Japanese journal of medical ultrasonics = 超音波医学 35, S321, 2008-04-15
  • NAID 10023914867
  • Duchenne 型筋ジストロフィーに併発した上腸間膜動脈症候群に対し胃空腸吻合術が有効であった1例
  • 境澤 隆夫,中山 中,大野 康成,竹内 信道,伊藤 憲雄,辻本 和雄
  • 日本臨床外科学会雑誌 = The journal of the Japan Surgical Association 68(8), 1966-1969, 2007-08-25
  • NAID 10019821232


Duchenne's Muscular DystrophyDuchenne's Muscular DystrophyDuchenne’s Muscular DystrophyDuchenne Muscular DystrophyDuchenne muscular dystrophyDuchenne Muscular Dystrophy (DMD). Causes




X-linked recessive disorder

X-linked recessive disorders (first aid step p.109)

Female carriers of X-linked recessive disorders are rarely affected because of random inactivation of X chromosomes in each cell.



  • v.

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「to make melodious sounds; "The nightingale was singing"」

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「『歌う』;(…に)歌って聞かせる《+『to』(『for』)+『名』》;(楽器に合わせて)歌う《+『to』+『名』》・〈小鳥・虫などが〉『鳴く』,さえずる / 《文》(…を)詩(歌)にする,(詩(歌)を詠んで)賛美する《+『of』+『名』》・〈小川・風・弾丸・湯沸かし・耳などが〉歌うように鳴る・《米語》自白する;密告する・〈歌〉‘を'歌う・《副詞[句]を伴って》歌って…‘を'(…に)する・…‘を'唱える,詠唱する・《文》…‘を'詩(歌)にする,(詩(歌)に詠んで)賛美する・合唱の集い」

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「deliver by singing; "Sing Christmas carols"」

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「produce tones with the voice; "She was singing while she was cooking"; "My brother sings very well"」



  • n.
  • (医)栄養失調、栄養失調症。(医)異栄養、異栄養症、ジフトロフィー

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「any degenerative disorder resulting from inadequate or faulty nutrition」

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「栄養障害 / 筋萎縮症,筋ジストロフィー(筋肉の退化・萎縮・運動障害などが起こる病気)」



  • adj.
  • 筋肉の、筋の

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「of or relating to or consisting of muscle; "muscular contraction"」

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「『助肉の』,筋肉でできた / 筋肉による / 筋肉の発達した」

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「having or suggesting great physical power or force; "the muscular and passionate Fifth Symphony"」



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「the 19th letter of the Roman alphabet」

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「sulfurの化学記号 / {略}South[ern]」



single strandsingle-strandsingle-stranded