WordNet

(embryology) the repeated division of a fertilised ovum (同)segmentation
the breaking of a chemical bond in a molecule resulting in smaller molecules
the state of being split or cleft; "there was a cleavage between the liberal and conservative members"
the act of cleaving or splitting
the line formed by a groove between two parts (especially the separation between a womans breasts)
the 4th letter of the Roman alphabet (同)d

PrepTutorEJDIC

割る(割れる)こと;割れ(裂け)目 / 卵割(受精卵の細胞分裂) / (鉱物の結晶の)劈開(へきかい) / 《話》(大きなえりぐりのドレスから見える)乳房の谷間
deuteriumの化学記号
deoxyribonucleic acidディオキシリボ核酸

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A label-free DNA-templated silver nanocluster probe for fluorescence on-off detection of endonuclease activity and inhibition.

Qian Y, Zhang Y, Lu L, Cai Y.SourceKey Laboratory of Applied Surface and Colloid Chemistry of Ministry of Education, Shaanxi Normal University, PR China; Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, PR China.
Biosensors & bioelectronics.Biosens Bioelectron.2014 Jan 15;51:408-12. doi: 10.1016/j.bios.2013.07.060. Epub 2013 Aug 6.
Endonuclease cleavage of DNA plays an important role in biological and medicinal chemistry. This study aimed to develop a reliable and sensitive method for nuclease activity assay by combining the high specificity of DNA cleavage reactions with ultrahigh fluorescence turn-on abilities of guanine-ric
PMID 24001584

Fluorescence correlation spectroscopy analysis for accurate determination of proportion of doubly labeled DNA in fluorescent DNA pool for quantitative biochemical assays.

Hou S, Sun L, Wieczorek SA, Kalwarczyk T, Kaminski TS, Holyst R.SourceInstitute of Physical Chemistry PAS, Kasprzaka 44/52, 01-224 Warsaw, Poland. Electronic address: hs0010910@gmail.com.
Biosensors & bioelectronics.Biosens Bioelectron.2014 Jan 15;51:8-15. doi: 10.1016/j.bios.2013.07.010. Epub 2013 Jul 18.
Fluorescent double-stranded DNA (dsDNA) molecules labeled at both ends are commonly produced by annealing of complementary single-stranded DNA (ssDNA) molecules, labeled with fluorescent dyes at the same (3' or 5') end. Because the labeling efficiency of ssDNA is smaller than 100%, the resulting dsD
PMID 23920090

Novel mixed ligand complexes of bioactive Schiff base (E)-4-(phenyl (phenylimino) methyl) benzene-1,3-diol and 2-aminophenol/2-aminobenzoic acid: Synthesis, spectral characterization, antimicrobial and nuclease studies.

Subbaraj P, Ramu A, Raman N, Dharmaraja J.SourceDepartment of Chemistry, Devanga Arts College, Aruppukottai 626 101, Tamil Nadu, India.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2014 Jan 3;117:65-71. doi: 10.1016/j.saa.2013.07.096. Epub 2013 Aug 8.
A novel bidentate Schiff base ligand has been synthesized using 2,4-dihydroxybenzophenone and aniline. Its mixed ligand complexes of MAB type [M=Mn(II), Co(II), Ni(II), Cu(II) and Zn(II); HA=Schiff base and B=2-aminophenol/2-aminobenzoic acid] have been synthesized and characterized on the basis of
PMID 23981416

西増弘志
日本結晶学会誌 57(2), 96-103, 2015
… Cas9 is an RNA-guided DNA endonuclease and is implicated in the bacterial CRISPR-Cas adaptive immune system. … Cas9 binds dual guide RNAs or single-guide RNA, and the Cas9-RNA complex recognizes and cleaves target double-stranded DNA via RNA-DNA complementarity. … To understand this unprecedented, RNA-guided DNA cleavage mechanism, we solved the crystal structure of Cas9 in complex with guide RNA and target DNA. …
NAID 130005067196

Nuclear dynamics of topoisomerase II beta reflects its catalytic activity that is regulated by binding of RNA to the C-terminal domain

Onoda Akihisa,Hosoya Osamu,Sano Kuniaki,Kiyama Kazuko,Kimura Hiroshi,Kawano Shinji,Furuta Ryohei,Miyaji Mary,Tsutsui Ken,Tsutsui Kimiko M.
Nucleic Acids Research 42(14), 9005-9020, 2014-07-17
… DNA topoisomerase II (topo II) changes DNA topology by cleavage/re-ligation cycle(s) and thus contributes to various nuclear DNA transactions. …
NAID 120005553910

Direct analysis of Holliday junction resolving enzyme in a DNA origami nanostructure.

Suzuki Yuki,Endo Masayuki,Cañas Cristina,Ayora Silvia,Alonso Juan C,Sugiyama Hiroshi,Takeyasu Kunio
Nucleic acids research 42(11), 7421-7428, 2014-05
… HJ resolving enzymes (resolvases) distort the junction structure upon binding and prior cleavage, raising the possibility that the reactivity of the enzyme can be affected by a particular geometry and topology at the junction. … Here, we employed a DNA origami nano-scaffold in which each arm of a HJ was tethered through the base-pair hybridization, allowing us to make the junction core either flexible or inflexible by adjusting the length of the DNA arms. …
NAID 120005458291