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Diabetes Control and Complications Trial
Diabetes Control and Complications Trial
Diabetes Control and Complications Trial

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/03/19 23:00:41」(JST)

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  • Delayed Gastric Emptying Is Associated With Early and Long-term Hyperglycemia in Type 1 Diabetes Mellitus.
  • Bharucha AE1, Batey-Schaefer B2, Cleary PA3, Murray JA4, Cowie C5, Lorenzi G6, Driscoll M7, Harth J7, Larkin M8, Christofi M8, Bayless M9, Wimmergren N10, Herman W11, Whitehouse F12, Jones K12, Kruger D12, Martin C11, Ziegler G13, Zinsmeister AR14, Nathan DM8; Diabetes Control and Complications Trial–Epidemiology of Diabetes Interventions and Complications Research Group.
  • Gastroenterology.Gastroenterology.2015 Aug;149(2):330-9. doi: 10.1053/j.gastro.2015.05.007. Epub 2015 May 14.
  • BACKGROUND & AIMS: After the Diabetes Control and Complications Trial (DCCT), the Epidemiology of Diabetes Interventions and Complications (EDIC) study continued to show persistent benefit of prior intensive therapy on neuropathy, retinopathy, and nephropathy in type 1 diabetes mellitus (DM). Th
  • PMID 25980755
  • Long-term Outcomes in Youths with Diabetes Mellitus.
  • White NH1.
  • Pediatric clinics of North America.Pediatr Clin North Am.2015 Aug;62(4):889-909. doi: 10.1016/j.pcl.2015.04.004. Epub 2015 May 23.
  • In this article, the author reviews the long-term outcomes and their precursors of type 1 diabetes starting in youth. The author also contrasts the changing incidence of these long-term complications as we have moved from the pre-Diabetes Control and Complications Trial (DCCT) to the post-DCCT stand
  • PMID 26210623
  • Prevalence and predictors of severe hypoglycemia in Danish children and adolescents with diabetes.
  • Johansen A1, Kanijo B1, Fredheim S1,2, Olsen B1, Hertz B3, Lauridsen MH3, Andersen M1, Mortensen HB1,2, Svensson J1,2; Danish Society for Diabetes in Childhood.
  • Pediatric diabetes.Pediatr Diabetes.2015 Aug;16(5):354-60. doi: 10.1111/pedi.12171. Epub 2014 Jul 12.
  • OBJECTIVE: To investigate the prevalence of severe hypoglycemia in Danish children and adolescents with type 1 diabetes and to pinpoint predictors of this acute complication in children on modern treatment modalities.RESEARCH DESIGN AND METHODS: The study is based on data from DanDiabKids, a nationa
  • PMID 25039921


  • 糖尿病合併症をいかに防ぐか 予防のエビデンスと戦略 (特集 時代とともに広がる「糖尿病合併症」の概念) -- (糖尿病合併症の予防と早期発見)
  • 西川 武志,荒木 栄一
  • 診断と治療 103(3), 290-296, 2015-03
  • NAID 40020390342
  • 小児・思春期糖尿病の治療目標 (第5土曜特集 糖尿病のすべて) -- (治療目標)
  • 血糖管理目標とエビデンス : DCCT, Kumamoto Study, UKPDS (第5土曜特集 糖尿病のすべて) -- (治療目標)
  • 石井 規夫,荒木 栄一
  • 医学のあゆみ 252(5), 521-527, 2015-01-31
  • NAID 40020344677


このように DCCT は糖尿病の合併症対策に明確な方向性を与えてくれましたが、それを実現するうえで低血糖の対策が欠かせないことも教えてくれました。合併症を抑えるためには血糖値をできるだけ低くしたい、ところが低血糖は ...
さて、糖尿病合併症はどうなりましたでしょうか。DCCT時代の「これまでの血糖コントロール群」は、HbA1cは良好になって8%になっているのですが、糖尿病網膜症も糖尿病腎症もそして大血管合併症(心筋梗塞、脳卒中など)、どれを ...


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