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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/07 08:04:20」(JST)

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Cyclopentolate is a medication commonly used during pediatric eye examinations that dilates the eye (mydriatic), prevents accommodation of the eye to different distances (cycloplegic), and blocks specific receptors called muscarinic receptors (muscarinic antagonist).^[1] Cyclopentolate is also administered as an atropine substitute to reverse muscarinic and central nervous system effects of indirect cholinomimetic (anti-AChase) administration.

When used in eye drops in paediatric eye examinations, cyclopentolate 0.5 percent and 1.0 percent is used to stop the eye focusing at any distance closer than infinity. This enables the ophthalmologist or optometrist to obtain a more accurate reading of the correcting lenses required for clear vision at distance. Brand names include Cyclogyl, Cylate, & Pentolair.^[2]

The drops take around 30–60 minutes to work and usually less than 24 hours (pupil dilation could last up to 96 hours) to wear off (with patients advised not to drive a vehicle or operate machinery for at least 12 hours). The pupils become wider when cyclopentolate is administered, making the eyes more sensitive to light. Close objects (and possibly distant objects) will also appear blurred.

Side effects to cyclopentolate are rare, but can include effects such as disorientation, incoherent speech or visual disturbances during the 24-hour period that the drug has an effect. The side effects are more common in children.

Pupil dilation (mydriasis) caused by cyclopentolate 1% instilled into both eyes

References

^ "Cyclopentolate". Retrieved June 15, 2012.
^ "cyclopentolate hydrochloride solution - ophthalmic, Cyclogyl, Cylate, Pentolair". Retrieved June 15, 2012.
^ John P.Whitcher, Paul Riordan-Eva. Vaughan & Asbury's general ophthalmology. (17th ed.). McGraw-Hill Medical. p. 63. ISBN 978-0071443142.

UpToDate Contents

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1. Amblyopia in children: Management and outcome
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4. 角膜剥離および角膜異物：マネージメント corneal abrasions and corneal foreign bodies management
5. 未熟児網膜症 retinopathy of prematurity

English Journal

The Influence of Induced Astigmatism on the Depth of Focus.

Leube A1, Ohlendorf A, Wahl S.
Optometry and vision science : official publication of the American Academy of Optometry.Optom Vis Sci.2016 Aug 17. [Epub ahead of print]
PURPOSE: To evaluate whether an induced astigmatism influences the subjective depth of focus.METHODS: Fifty-one participants aged 18 to 35 years and with a mean spherical equivalent refractive error of -0.51 ± 2.35 DS participated in the study. The accommodation was blocked with three drops of 1% c
PMID 27536975

A comparison of cycloplegic autorefraction and retinoscopy in Indian children.

Guha S1, Shah S2, Shah K3, Hurakadli P1, Majee D1, Gandhi S1.
Clinical & experimental optometry.Clin Exp Optom.2016 Jul 17. doi: 10.1111/cxo.12375. [Epub ahead of print]
BACKGROUND: Correction of significant refractive errors in childhood helps in preventing amblyopia and strabismus. India has a huge demand for eye-care services related to uncorrected refractive errors with limited manpower resources. This can be overcome by autorefractors, which are free of operato
PMID 27426488

The effect of topical anti-muscarinic agents on subfoveal choroidal thickness in healthy adults.

Öner V1, Bulut A1, Öter K1.
Eye (London, England).Eye (Lond).2016 Jul;30(7):925-8. doi: 10.1038/eye.2016.61. Epub 2016 Apr 8.
PurposeTo investigate the effects of tropicamide and cyclopentolate, which are two anti-muscarinic agents commonly used in the ophthalmologic practice, on subfoveal choroidal choroidal thickness (ChT) in healthy adults.MethodsA total of 74 healthy adult subjects were enrolled in the study. Subjects
PMID 27055680

Japanese Journal

視能矯正を考える　視覚障害

日本視能訓練士協会誌 23, 46-55, 1995
NAID 130003645838

小児における1%サイクロジールによる屈折検査の検討

日本視能訓練士協会誌 9(1), 24-28, 1981
NAID 130003646179

NeosynephrinおよびCyclogyl点眼後の眼内温度勾配

日本眼科学会雑誌 81(5), p413-418, 1977-05
NAID 40002850888

Related Pictures

CYCLOGYL CYCLOPENTOLATE OPHTHALMIC SOLUTION ALCON 15ML - Pharma Thai Store Cyclogyl ophthalmic : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing cyclopentolate ophthalmic : Uses, Side Effects, Interactions, Pictures, Warnings Cyclogyl Ophthalmic - patient information, description, dosage and directions. Cyclogyl Eye Drops 1% 15ml Cyclogyl, (Cyclopentolate HCl), 1%, Opthalmic Solution, 5mL Bottle | McGuff Medical RX Coupons

★リンクテーブル★

リンク元	「シクロペントラート」

「シクロペントラート」

Cyclopentolate
Systematic (IUPAC) name
	(RS)-2-(dimethylamino)ethyl (1-hydroxycyclopentyl)(phenyl)acetate
Clinical data
Pregnancy; category	C;
Routes of; administration	Topic
Identifiers
CAS Number	512-15-2
ATC code	S01FA04
PubChem	CID 2905
DrugBank	DB00979
ChemSpider	2802
UNII	I76F4SHP7J
KEGG	D07759
ChEBI	CHEBI:4024
ChEMBL	CHEMBL1200473
Chemical data
Formula	C17H25NO3
Molar mass	291.385 g/mol
	SMILES O=C(OCCN(C)C)C(c1ccccc1)C2(O)CCCC2 ;
	InChI InChI=1S/C17H25NO3/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3 ; Key:SKYSRIRYMSLOIN-UHFFFAOYSA-N ;
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　　[★]

英: cyclopentolate
化: 塩酸シクロペントラート
商: サイプレジン、Cyclogyl, AK-Pentolate
関: ムスカリン受容体

ムスカリン受容体拮抗薬

散瞳薬

[1] "Cyclopentolate". Retrieved June 15, 2012.

[2] "cyclopentolate hydrochloride solution - ophthalmic, Cyclogyl, Cylate, Pentolair". Retrieved June 15, 2012.

[vaughan-3] John P.Whitcher, Paul Riordan-Eva. Vaughan & Asbury's general ophthalmology. (17th ed.). McGraw-Hill Medical. p. 63. ISBN 978-0071443142.

匿名

検索

案内

案内

Cyclogyl