WordNet

any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
the basic unit of money in Papua New Guinea

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1. 避妊の概要 overview of contraception
2. 炭疽菌の微生物学、病因、および疫学 microbiology pathogenesis and epidemiology of anthrax
3. B群レンサ球菌感染症予防のための予防接種 vaccines for the prevention of group b streptococcal disease
4. 皮膚リーシュマニア症の治療 treatment of cutaneous leishmaniasis
5. クロイツフェルト・ヤコブ病 creutzfeldt jakob disease

CDK14 Contributes to Reactive Gliosis via Interaction with Cyclin Y in Rat Model of Spinal Cord Injury.

Duan C1, Liu Y, Lu L, Cai R, Xue H, Mao X, Chen C, Qian R, Zhang D, Shen A.
Journal of molecular neuroscience : MN.J Mol Neurosci.2015 Aug 28. [Epub ahead of print]
Cyclin-dependent kinases (CDKs) are perceived as the engine that drives cell cycle progression whereas cyclins are considered to be the gears that are changed to aid the transition between cycle phases. CDK14 is a cdc2-related serine/threonine protein kinase and plays an important role in normal cel
PMID 26315607

Long G2 accumulates recombination intermediates and disturbs chromosome segregation at dysfunction telomere in Schizosaccharomyces pombe.

Habib AG1, Masuda K1, Yukawa M1, Tsuchiya E1, Ueno M2.
Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Aug 14;464(1):140-6. doi: 10.1016/j.bbrc.2015.06.098. Epub 2015 Jun 18.
Protection of telomere (Pot1) is a single-stranded telomere binding protein which is essential for chromosome ends protection. Fission yeast Rqh1 is a member of RecQ helicases family which has essential roles in the maintenance of genomic stability and regulation of homologous recombination. Double
PMID 26093291

Suppression of homologous recombination sensitizes human tumor cells to IGF-1R inhibition.

Lodhia KA1, Gao S, Aleksic T, Esashi F, Macaulay VM.
International journal of cancer. Journal international du cancer.Int J Cancer.2015 Jun 15;136(12):2961-6. doi: 10.1002/ijc.29327. Epub 2014 Nov 25.
Inhibition of type 1 IGF receptor (IGF-1R) sensitizes to DNA-damaging cancer treatments, and delays repair of DNA double strand breaks (DSBs) by non-homologous end-joining and homologous recombination (HR). In a recent screen for mediators of resistance to IGF-1R inhibitor AZ12253801, we identified
PMID 25388513

Molecular Responses of Human Lung Epithelial Cells to the Toxicity of Copper Oxide Nanoparticles Inferred from Whole Genome Expression Analysis

Hanagata Nobutaka,Zhuang Fei,Connolly Sarah,Li Jie,Ogawa Nobuhiro,Xu Mingsheng
ACS Nano 5(12), 9326-9338, 2011-11
… Cells that survived exposure to CuO-NPs arrested the cell cycle as a result of the downregulation of proliferating cell nuclear antigen (PCNA), cell division control 2 (CDC2), cyclin B1 (CCNB1), target protein for Xklp2 (TPX2), aurora kinase A (AURKA) and B (AURKB). … The downregulation of CDC2, CCNB1, TPX2, AURKA, and AURKB, the expressions of which are involved in cell cycle arrest, was attributed to Cu ions released from CuO-NPs into medium. …
NAID 120005008215

Regulation of Maternal Gene Expression by MEK/MAPK and MPF Signaling in Porcine Oocytes During In Vitro Meiotic Maturation

ZHANG Ding-Xiao,PARK Won-Jun,SUN Shao-Chen,XU Yong-Nan,LI Ying-Hua,CUI Xiang-Shun,KIM Nam-Hyung
The Journal of reproduction and development 57(1), 49-56, 2011-02-01
… Mitogen-activated protein kinase (MAPK) and maturation/M phase promoting factor (MPF) play crucial roles in oocyte meiotic maturation in mammals. … To explore the underlying molecular mechanisms, expression patterns and polyadenylation states of five representative maternal transcripts, icyclin B1, Cdc2, C-mos, GDF9/i and iBMP15/i, were examined by real-time PCR and poly(A)-test PCR (PAT assay). …
NAID 10027901064

Analyses of the Regulatory Mechanism of Porcine WEE1B: The Phosphorylation Sites of Porcine WEE1B and Mouse WEE1B Are Different

SHIMAOKA Takuma,NISHIMURA Takanori,KANO Kiyoshi,NAITO Kunihiko
Journal of Reproduction and Development 57(2), 223-228, 2011
… WEE1B, an oocyte-specific kinase, phosphorylates the CDC2 inhibitory site and maintains the meiotic arrest of oocytes at the first meiotic prophase in several mammalian species. … In the present study, we analyzed the regulation mechanisms of porcine WEE1B (pWEE1B), focusing on the cAMP-dependent protein kinase (PKA) phosphorylation site and intracellular localization. …
NAID 130000436819