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cytochrome P-450 CYP1A2
cytochrome C450 1A2

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/09 16:47:39」(JST)

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  • Genetic polymorphism analysis of the drug-metabolizing enzyme CYP1A2 in a Uyghur Chinese population: a pilot study.
  • Geng T1,2,3, Zhang XY1, Wang L4, Wang H1, Shi X1, Kang L4, Hou P1, Jin T1,4.
  • Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.2016 Jun;46(6):542-7. doi: 10.3109/00498254.2015.1089367. Epub 2015 Sep 18.
  • 1. CYP1A2 is a highly polymorphic gene and CYP1A2 enzyme results in broad inter-individual variability in response to certain pharmacotherapies, while little is known about the genetic variation of CYP1A2 in Uyghur Chinese population. The aim of the present study was to screen Uyghur volunteers fo
  • PMID 26383175
  • The different metabolism of morusin in various species and its potent inhibition against UDP-glucuronosyltransferase (UGT) and cytochrome p450 (CYP450) enzymes.
  • Shi X1,2, Yang S3, Zhang G4, Song Y5, Su D5, Liu Y5, Guo F1, Shan L1,2, Cai J1.
  • Xenobiotica; the fate of foreign compounds in biological systems.Xenobiotica.2016 May;46(5):467-76. doi: 10.3109/00498254.2015.1086839. Epub 2015 Sep 15.
  • 1. The aim of this study was to investigate the inhibitory effect of morusin on Glucuronosyltransferase (UGT) isoforms and cytochrome P450 enzymes (CYP450s). We also investigated the metabolism of morusin in human, rat, dog, monkey, and minipig liver microsomes. 2. 100 μM of morusin exhibited
  • PMID 26372370
  • Tandem mass spectrometric analysis of S- and N-linked glutathione conjugates of pulegone and menthofuran and identification of P450 enzymes mediating their formation.
  • Lassila T1,2, Mattila S1, Turpeinen M2,3, Pelkonen O2, Tolonen A4.
  • Rapid communications in mass spectrometry : RCM.Rapid Commun Mass Spectrom.2016 Apr 15;30(7):917-26. doi: 10.1002/rcm.7518.
  • RATIONALE: Menthofuran is a hepatotoxin and a major metabolite of pulegone, a monoterpene found in the essential oils of many mint species. It is bioactivated by cytochrome P450 (CYP) enzymes to reactive metabolites, which may further react with glutathione to form S-linked and N-linked conjugates.
  • PMID 26969934


  • Neutralization of ADAM8 ameliorates liver injury and accelerates liver repair in carbon tetrachloride-induced acute liver injury
  • Li San-Qiang,Zhu Sha,Wan Xue-Dong [他]
  • The Journal of toxicological sciences : an official journal of the Japanese Society of Toxicology 39(2), 339-351, 2014-04
  • NAID 40020063625
  • Genetic polymorphism of cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 genes modulate susceptibility to gastric cancer in patients with Helicobacter pylori infection
  • Ghoshal Ujjala,Tripathi Shweta,Kumar Sushil [他]
  • Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 17(2), 226-234, 2014
  • NAID 40020215995
  • Effect of eurycomanone on cytochrome P450 isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 in vitro
  • Pan Yan,Tiong Kai Hung,Abd-Rashid Badrul Amini [他]
  • Journal of natural medicines 68(2), 402-406, 2014
  • NAID 40020023336




拡張検索CYP1A2タンパク質」「チトクロムP450酵素CYP1A2」「cytochrome P-450 CYP1A2



  • CYP1A2



cytochrome P-450 CYP1A2

cytochrome P-450 CYP1A2」




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