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- glatiramer acetate
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English Journal
- Synthesis of β-Cyclodextrin Containing Copolymer via "Click" Chemistry and Its Self-Assembly in the Presence of Guest Compounds.
- Zhang J, Ellsworth K, Ma PX.SourceDepartment of Biologic and Materials Sciences, University of Michigan, Ann Arbor, MI 48109, USA; Fax: +1 734 647 2110; Department of Pharmaceutics, College of Pharmacy, Third Military Medical University, Chongqing 400038, P.R. China.
- Macromolecular rapid communications.Macromol Rapid Commun.2012 Apr 23;33(8):664-71. doi: 10.1002/marc.201100814. Epub 2012 Feb 9.
- We report the synthesis of a hydrophilic copolymer with one polyethylene glycol (PEG) block and one β-cyclodextrin (β-CD) containing block by a "click" reaction between azido-substituted β-CD and propargyl flanking copolymer. (1) H NMR study suggested a highly efficient conjugation of β-CD units
- PMID 22318939
- Novel biomimetic vectors with endosomal-escape agent enhancing gene transfection efficiency.
- Sun X, Liu C, Liu D, Li P, Zhang N.SourceThe School of Pharmaceutical Science, Shandong University, 44 Wenhua Xi Road, Ji'nan, Shandong Province 250012, China.
- International journal of pharmaceutics.Int J Pharm.2012 Apr 4;425(1-2):62-72. Epub 2012 Jan 14.
- Low cytotoxicity and high transfection efficiency are critical issues in designing current non-viral gene delivery vectors. In the present study, a novel biomimetic lipid-polycation copolymer, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-graft-poly(l-lysine)-block-poly(ethylene glycol) (DOPE-g-PLL-
- PMID 22266532
Japanese Journal
- Glatiramer acetate treatment does not modify the clinical course of (NZB×BXSB)F1 lupus murine model
- BOREL Paula,BENKHOUCHA Mahdia,WEBER Martin S.,ZAMVIL Scott S.,SANTIAGO-RABER Marie-Laure,LALIVE Patrice H.
- International immunology 20(10), 1313-1319, 2008-10-01
- NAID 10024357255
- Treatment of multiple sclerosis with Copolymer-1 (Copaxone) : implicating mechanisms of T_h1 to T_h2/T_h3 immune-deviation
Related Links
- Glatiramer acetate (also known as Copolymer 1, Cop-1, or Copaxone - as marketed by Teva Pharmaceuticals) is an immunomodulator drug currently used to treat multiple sclerosis. It is a random polymer of four amino acids found in myelin ...
- Find information about COPAXONE® (glatiramer acetate injection) along with free resources and support.
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