WordNet

the 3rd letter of the Roman alphabet (同)c
(music) the keynote of the scale of C major
a general-purpose programing language closely associated with the UNIX operating system
an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm

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1. 小児における中枢神経系腫瘍の臨床症状および診断 clinical manifestations and diagnosis of central nervous system tumors in children
2. 脳腫瘍の臨床所見および診断 clinical presentation and diagnosis of brain tumors
3. 小児における中枢神経系腫瘍の疫学 epidemiology of central nervous system tumors in children
4. 小児における中枢神経系腫瘍のマネージメントに関する概要 overview of the management of central nervous system tumors in children
5. 原発性脳腫瘍の発生率 incidence of primary brain tumors

CREKA peptide-conjugated dendrimer nanoparticles for glioblastoma multiforme delivery.

Zhao J1, Zhang B1, Shen S1, Chen J1, Zhang Q1, Jiang X1, Pang Z2.
Journal of colloid and interface science.J Colloid Interface Sci.2015 Jul 15;450:396-403. doi: 10.1016/j.jcis.2015.03.019. Epub 2015 Mar 23.
Glioblastoma multiforme (GBM) is the most aggressive central nervous system (CNS) tumor because of its fast development, poor prognosis, difficult control and terrible mortality. Poor penetration and retention in the glioblastoma parenchyma were crucial challenges in GBM nanomedicine therapy. Nanopa
PMID 25863222

Detection of Merkel cell polyomavirus large T-antigen sequences in human central nervous system tumors.

Sadeghi F1, Salehi-Vaziri M, Alizadeh A, Ghodsi SM, Bokharaei-Salim F, Fateh A, Monavari SH, Keyvani H.
Journal of medical virology.J Med Virol.2015 Jul;87(7):1241-7. doi: 10.1002/jmv.24178. Epub 2015 Mar 9.
Despite decades of epidemiological investigation, little is known about the etiology of the central nervous system (CNS) tumors, and few well-established risk factors have been recognized. This study tested the presence of Merkel cell polyomavirus (MCPyV), the only member of the Polyomaviridae famil
PMID 25754536

Somatostatin prevents lipopolysaccharide‑induced neurodegeneration in the rat substantia nigra by inhibiting the activation of microglia.

Bai L1, Zhang X1, Li X1, Liu N1, Lou F1, Ma H1, Luo X1, Ren Y1.
Molecular medicine reports.Mol Med Rep.2015 Jul;12(1):1002-8. doi: 10.3892/mmr.2015.3494. Epub 2015 Mar 13.
Somatostatin (SST) is a neuromodulator which is abundant throughout the central nervous system (CNS) and has a crucial role in neurodegenerative disorders. However, little is known about the effects and mechanisms of SST in dopaminergic (DA) neurons in the context of Parkinson's disease (PD). In the
PMID 25777539

Inflammatory reaction regulated by microglia plays a role in atrazine-induced dopaminergic neuron degeneration in the substantia nigra

Zhang Bo,Ma Kun,Li Baixiang
The Journal of Toxicological Sciences 40(4), 437-450, 2015
… As the primary immunocytes in the central nervous system (CNS), microglial function to maintain the CNS microenvironment by preventing damage to healthy cells as well by regulating inflammatory responses. … Moreover, as two major inflammatory cytokines, expression of tumor necrosis factor α and interleukin-1β, emerged earlier post-ATR exposure, and a significant upregulation was observed in the medium and high ATR exposure groups. …
NAID 130005087449

近藤智正,大重英行,亀井孝昌,武田純一,吉村晋一,淺井昭雄
Neuro-Oncologyの進歩 22(1), 26-30, 2015
… Primary central nervous system(CNS)angiosarcoma is extremely rare. … Thirty three patients with primary CNS angiosarcoma have been reported. … therefore we selected conservative therapy.Microscopically, the tumor cells showed an abortive vascular structure, and positive immunohistochemical staining for cluster of differentiation(CD)31, CD34, and p53. … Systematic screening by CT examination did not detect any mass lesion except the brain tumor. …
NAID 130005075311

Central Nervous System Manifestations of Tuberculosis-associated Immune Reconstitution Inflammatory Syndrome during Adalimumab Therapy: A Case Report and Review of the Literature

Tanaka Toru,Sekine Akimasa,Tsunoda Yoshiya,Takoi Hiroyuki,Lin Shin-Yuan,Yatagai Yohei,Hayasihara Kenji,Saito Takefumi
Internal Medicine 54(7), 847-851, 2015
… A 64-year-old neurologically asymptomatic woman with rheumatoid arthritis who was treated with the tumor necrosis factor (TNF)-α antagonist adalimumab developed disseminated tuberculosis (TB). … In addition, careful screening for central nervous system (CNS) TB should be performed prior to the initiation of therapy, as even neurologically asymptomatic patients can develop CNS manifestations of IRIS. …
NAID 130005063225