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- certificate of deposit / (また『C.D.』)Civil Defense民間防衛
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- 1. 分類不能型低ガンマグロブリン血症の病因 pathogenesis of common variable immunodeficiency
- 2. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
- 3. 原発性の体液性免疫不全：概要 primary humoral immune deficiencies an overview
- 4. 慢性リンパ性白血病の病理学的特徴、診断、および鑑別診断 pathologic features diagnosis and differential diagnosis of chronic lymphocytic leukemia
- 5. 節外（MALT）および節性濾胞辺縁帯リンパ腫の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of extranodal malt and nodal marginal zone lymphomas
English Journal
- FHR3 Blocks C3d-Mediated Coactivation of Human B Cells.
- Buhlmann D1, Eberhardt HU1, Medyukhina A2, Prodinger WM3, Figge MT4, Zipfel PF5, Skerka C6.
- Journal of immunology (Baltimore, Md. : 1950).J Immunol.2016 Jun 8. pii: 1600053. [Epub ahead of print]
- The autoimmune renal disease deficient for complement factor H-related (CFHR) genes and autoantibody-positive form of hemolytic uremic syndrome is characterized by the presence of autoantibodies specific for the central complement regulator, factor H, combined with a homozygous deficiency, mostly in
- PMID 27279373
- Genes associated with common variable immunodeficiency: one diagnosis to rule them all?
- Bogaert DJ1, Dullaers M2, Lambrecht BN3, Vermaelen KY4, De Baere E5, Haerynck F6.
- Journal of medical genetics.J Med Genet.2016 Jun 1. pii: jmedgenet-2015-103690. doi: 10.1136/jmedgenet-2015-103690. [Epub ahead of print]
- Common variable immunodeficiency (CVID) is a primary antibody deficiency characterised by hypogammaglobulinaemia, impaired production of specific antibodies after immunisation and increased susceptibility to infections. CVID shows a considerable phenotypical and genetic heterogeneity. In contrast to
- PMID 27250108
- CD21-/low B cells in human blood are memory cells.
- Thorarinsdottir K1,2, Camponeschi A1,3, Cavallini N1, Grimsholm O1, Jacobsson L1,2, Gjertsson I1,2, Mårtensson IL1.
- Clinical and experimental immunology.Clin Exp Immunol.2016 Mar 24. doi: 10.1111/cei.12795. [Epub ahead of print]
- The complement receptor 2 (CR2, CD21) is part of a complex (CD21/CD19/CD81) acting as a co-receptor to the B-cell receptor (BCR). Simultaneous triggering of the BCR and CD21 lowers the threshold for B-cell activation. Although CD21 is important, B cells that express low amounts or lack surface CD21
- PMID 27010233
Japanese Journal
- Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu 13 complex requires the cytoplasmic domain of CD19
- J. Immunol. 159, 3278, 1997
- NAID 80009986230
- Regulation of B lymphocyte development and activation by the CD19/CD21/CD81/Leu-13 complex requires the cytoplasmic domain of CD19
- J Immunol 159, 3278-3287, 1997
- NAID 10012783413
Related Links
- It primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation ... "The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules".
Related Pictures
★リンクテーブル★
| 関連記事 | 「CD19」「CD21」「CD2」「CD1」「CD」 |
「CD19」
- 同
- B4
- B-cell co-receptor
発現細胞
機能
- Forms complex with CD21(CR2) and CD81(TAPA-1); co-receptor for B-cell--cytoplasmic domain binds cytoplasmic tyrosine kinases and PI 3-kinase
- CD21(CR2)にC3dが結合するとCD19の細胞内領域がリン酸化され、Src-family kinase(Lyn etc.)やPI 3-kinaseをリクルートし、PI 3-kinaseは下流にシグナルを伝達する
「CD21」
- 同
- CR2
発現細胞
- 成熟B細胞
分子量
- 145 kDa
機能
ファミリー
- 同
- CR2, Epstein-Barr virus receptor, C3d receptor
- 同
- CR2
「CD2」
発現細胞
分子量
- 45-58
機能
- リンパ球が抗原提示細胞と相互作用するのに重要 (IMM.343)
別名
- LFA-2, T11
ファミリー
- immunoglobulin
「CD1」
- 同
- leucine-6, CD1A through E
種類
- CD1a, CD1b, CD1c, CD1d
発現組織
- 胸腺皮質、ランゲルハンス細胞、樹状細胞、B細胞(CD1c)、腸上皮、平滑筋、血管上皮(CD1d)
分子量
- 43-49
機能
- MHC class I-like molecule, associated with β2-microgloulin. Has specialized role in presentation of lipid antigens
「CD」