WordNet

the 3rd letter of the Roman alphabet (同)c
(music) the keynote of the scale of C major
a general-purpose programing language closely associated with the UNIX operating system
(medicine) the act of caring for someone (as by medication or remedial training etc.); "the quarterback is undergoing treatment for a knee injury"; "he tried every treatment the doctors suggested"; "heat therapy gave the best relief"

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1. 初期乳癌に行う術後補助化学療法の急性の副作用 acute side effects of adjuvant chemotherapy for early stage breast cancer
2. 女性の転移性乳癌に対する全身療法：化学療法 systemic treatment of metastatic breast cancer in women chemotherapy
3. 妊娠期乳癌：治療 gestational breast cancer treatment
4. 高齢者における癌に対する全身化学療法 systemic chemotherapy for cancer in elderly persons
5. 化学療法に関連した経口毒性 oral toxicity associated with chemotherapy

Sphingosine kinase 1 is required for TGF-β mediated fibroblastto- myofibroblast differentiation in ovarian cancer.

Beach JA1,2, Aspuria PP1, Cheon DJ1, Lawrenson K1, Agadjanian H1, Walsh CS1,3, Karlan BY1,3, Orsulic S1,3.
Oncotarget.Oncotarget.2015 Dec 21. doi: 10.18632/oncotarget.6703. [Epub ahead of print]
Sphingosine kinase 1 (SPHK1), the enzyme that produces sphingosine 1 phosphate (S1P), is known to be highly expressed in many cancers. However, the role of SPHK1 in cells of the tumor stroma remains unclear. Here, we show that SPHK1 is highly expressed in the tumor stroma of high-grade serous ovaria
PMID 26716409

A plasma cytokine and angiogenic factor (CAF) analysis for selection of bevacizumab therapy in patients with metastatic colorectal cancer.

Bai L1,2, Wang F1,2, Zhang DS1,2, Li C3, Jin Y1,2, Wang DS1,2, Chen DL1,2, Qiu MZ1,2, Luo HY1,2, Wang ZQ1,2, Li YH1,2, Wang FH1,2, Xu RH1,2.
Scientific reports.Sci Rep.2015 Dec 1;5:17717. doi: 10.1038/srep17717.
This study intends to identify biomarkers that could refine the selection of patients with metastatic colorectal cancer (mCRC) for bevacizumab treatment. Pretreatment 36 plasma cytokines and angiogenic factors (CAFs) were first measured by protein microarray analysis in patients who received first-l
PMID 26620439

Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer.

Schmitz S1,2, Bindea G3,4,5, Albu RI1, Mlecnik B3,4,5, Machiels JP1,2.
Oncotarget.Oncotarget.2015 Oct 27;6(33):34288-99. doi: 10.18632/oncotarget.5924.
PURPOSE: To investigate if cetuximab induces epithelial to mesenchymal transition (EMT) and activation of cancer associated fibroblast (CAF) in the tumors of patients with squamous cell carcinoma of the head and neck (SCCHN).METHODS: Cetuximab was administered for two weeks prior to surgery to 20 tr
PMID 26437222

Current Status of Primary Prevention of Sudden Cardiac Death With Implantable Cardioverter Defibrillator in Patients With Chronic Heart Failure:– A Report From the CHART-2 Study –

, , , , , , , , ,
Circulation Journal 79(2), 381-390, 2015
… During the (median) 3.2-year follow-up, 79 fatal arrhythmic events (FAE), defined as composite of sudden cardiac/arrhythmic death, ventricular tachycardia/fibrillation and appropriate ICD therapy, occurred. … In the groups A and B combined, chronic atrial fibrillation (cAF) and left ventricular end-diastolic dimension (LVDd) ≥65 mm were independent predictors of FAE, and, when combined, their prognostic impact was highly significant (hazard ratio, 7.01; …
NAID 130004927045

Status of Primary Prevention of Sudden Cardiac Death With Implantable Cardioverter Defibrillator in Patients With Chronic Heart Failure:– Report From the CHART-2 Study –

, , , , , , , , ,
Circulation Journal, 2014
… During the (median) 3.2-year follow-up, 79 fatal arrhythmic events (FAE), defined as composite of sudden cardiac/arrhythmic death, ventricular tachycardia/fibrillation and appropriate ICD therapy, occurred. … In the groups A and B combined, chronic atrial fibrillation (cAF) and left ventricular end-diastolic dimension (LVDd) ≥65 mm were independent predictors of FAE, and, when combined, their prognostic impact was highly significant (hazard ratio, 7.01; …
NAID 130004704041

Journal of Arrhythmia 27(Supplement), APSY5_1-APSY5_1, 2011
… Nevertheless the majority of studies used to support ablative therapy track outcomes for no more than one year. … In the STOP AF trial, 69.9% of patients were AF free following cryo balloon ablation compared with 7.3% of patients commonly treated with antiarrhythmic drug therapy. … In other clinical trials, the success rate for drug therapy has been in the 10–30% range. …
NAID 130002129548