- 同
- CSK
- 同
- CSK
WordNet
- relating to or occurring in a term or fixed period of time; "terminal examinations"; "terminal payments"
- a contact on an electrical device (such as a battery) at which electric current enters or leaves (同)pole
- station where transport vehicles load or unload passengers or goods (同)terminus, depot
- electronic equipment consisting of a device providing access to a computer; has a keyboard and display
- being or situated at an end; "the endmost pillar"; "terminal buds on a branch"; "a terminal station"; "the terminal syllable"
- causing or ending in or approaching death; "a terminal patient"; "terminal cancer"
- of or relating to or situated at the ends of a delivery route; "freight pickup is a terminal service"; "terminal charges"
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- the 19th letter of the Roman alphabet (同)s
- an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
PrepTutorEJDIC
- 『終りの』,末端の / 毎期の,定期の;学期末の / 『死に至る』, / 末端 / (電池の)端子 / (町の中心に近い)空港バス発着場;(一般に,鉄道・バスの)終点,終着駅
- carbonの化学記号
- sulfurの化学記号 / {略}South[ern]
UpToDate Contents
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- 1. ホスホグリセリン酸キナーゼ欠損症およびホスホグリセリン酸ムターゼ欠損症 phosphoglycerate kinase deficiency and phosphoglycerate mutase deficiency
- 2. 心筋障害のバイオマーカーとしてのトロポニンおよびクレアチンキナーゼ troponins and creatine kinase as biomarkers of cardiac injury
- 3. 未分化リンパ腫キナーゼ（ALK）融合癌遺伝子陽性非小細胞肺癌 anaplastic lymphoma kinase alk fusion oncogene positive non small cell lung cancer
- 4. 頭頸部の扁平上皮癌化：分子学的および遺伝学的変化 head and neck squamous cell carcinogenesis molecular and genetic alterations
- 5. 心臓の虚血性再潅流障害 ischemic reperfusion injury of the heart
English Journal
- Csk regulates angiotensin II-induced podocyte apoptosis.
- Zhang L1, Ren Z1, Yang Q1, Ding G2.
- Apoptosis : an international journal on programmed cell death.Apoptosis.2016 Jul;21(7):846-55. doi: 10.1007/s10495-016-1256-z.
- Increasing data have shown that angiotensin II (Ang II) perpetuates podocyte injury and promotes progression to end-stage kidney disease. The mechanism underlying Ang II-induced podocyte apoptosis has not been established. C-terminal Src kinase (Csk) is a cytoplasmic kinase that interacts with scaff
- PMID 27225249
- Constitutive Lck Activity Drives Sensitivity Differences between CD8+ Memory T Cell Subsets.
- Moogk D1, Zhong S1, Yu Z2, Liadi I3, Rittase W4, Fang V5, Dougherty J1, Perez-Garcia A1, Osman I6, Zhu C4, Varadarajan N3, Restifo NP2, Frey AB7, Krogsgaard M8.
- Journal of immunology (Baltimore, Md. : 1950).J Immunol.2016 Jun 6. pii: 1600178. [Epub ahead of print]
- CD8+ T cells develop increased sensitivity following Ag experience, and differences in sensitivity exist between T cell memory subsets. How differential TCR signaling between memory subsets contributes to sensitivity differences is unclear. We show in mouse effector memory T cells (TEM) that >50%
- PMID 27271569
- Csk-mediated EPIYA phosphorylation of Pragmin creates a feed-forward Csk activation loop that promotes cell motility.
- Senda Y1, Murata-Kamiya N1, Hatakeyama M1.
- Cancer science.Cancer Sci.2016 Apr 26. doi: 10.1111/cas.12962. [Epub ahead of print]
- Pragmin is one of the few mammalian proteins containing the Glu-Pro-Ile-Tyr-Ala (EPIYA) tyrosine-phosphorylation motif that was originally discovered in the Helicobacter pylori CagA oncoprotein. Upon delivery into gastric epithelial cells via type IV secretion and subsequent tyrosine phosphorylation
- PMID 27116701
Japanese Journal
- Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells.
- Ikeda Osamu,Sekine Yuichi,Mizushima Akihiko,Nakasuji Misa,Miyasaka Yuto,Yamamoto Chikako,Muromoto Ryuta,Nanbo Asuka,Oritani Kenji,Yoshimura Akihiko,Matsuda Tadashi
- The Journal of Biological Chemistry 285(49), 38093-38103, 2010-12-06
- … Signal transducing adaptor protein-2 (STAP-2) is a recently identified adaptor protein, which contains pleckstrin homology (PH) and Src homology 2 (SH2)-like domains, as well as a signal transducer and an activator of transcription 3 (STAT3)-binding motif in its C-terminal region. … STAP-2 is also a substrate of breast tumor kinase (Brk). …
- NAID 80021491949
- A Silent Mutation Made Possible Efficient Production of Active Human Frk Tyrosine Kinase in Escherichia coli
- Yang Xiaoyan,Kinoshita Takayoshi,Gouda Masaki [他],YOKOTA Koichi,TADA Toshiji
- Bioscience, biotechnology, and biochemistry 74(1), 125-128, 2010-01-23
- … Fyn-related kinase (Frk) was first identified using human breast cancer cells. … It shares 51% identity with c-Src. … Like all members of the Src family, Frk is thought to cause several cancers <I>via</I> …
- NAID 10027550311
- STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation
- Ikeda Osamu,Miyasaka Yuto,Sekine Yuichi,Mizushima Akihiro,Muromoto Ryuta,Nanbo Asuka,Yoshimura Akihiko,Matsuda Tadashi
- Biochemical and Biophysical Research Communications 384(1), 71-75, 2009-06-19
- … Signal transducing adaptor protein-2 (STAP-2) is a recently identified adaptor protein that contains Pleckstrin and Src homology 2 (SH2)-like domains as well as a YXXQ motif in its C-terminal region. … STAP-2 is also known as breast tumor kinase (Brk) substrate (BKS). …
- NAID 120001311775
Related Links
- Carboxy-terminal Src kinase (Csk) is a negative regulator of Src family kinases, which play pivotal roles in controlling cell adhesion, migration, and cancer progression. To elucidate the in vivo role of Csk in epithelial ...
- 1. Growth Factors. 2005 Sep;23(3):233-44. C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)--endogenous negative regulators of Src-family protein kinases. Chong YP, Mulhern TD, Cheng HC. Bio21 ...
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| 関連記事 | 「terminal」「C」「Src kinase」「kinase」「S」 |
「terminal」
- n.
- adj.
- 終端の、終末の、末期の
- 関
- distal、end、end stage、ending、extremity、full-blown、terminal region、terminal stage、terminally、termini、terminus
「C」
- 炭素 carbon
- シトシン cytosine
- システイン cysteine
- シチジン
- セルシウス度 摂氏 degrees Celsius degree C
- 産婦人科領域で「子宮外頚 子宮外頚部 exocervix」を表現するための略語
「Src kinase」
「kinase」
[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase
「S」