Bordetella pertussis infection

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  • The Bordetella pertussis Type III Secretion System Tip Complex Protein Bsp22 Is Not a Protective Antigen and Fails To Elicit Serum Antibody Responses during Infection of Humans and Mice.
  • Villarino Romero R, Bibova I, Cerny O, Vecerek B, Wald T, Benada O, Zavadilova J, Osicka R, Sebo P.SourceInstitute of Microbiology of the ASCR, Prague, Czech Republic.
  • Infection and immunity.Infect Immun.2013 Aug;81(8):2761-7. doi: 10.1128/IAI.00353-13. Epub 2013 May 20.
  • The type III secretion system (T3SS) of pathogenic bordetellae employs a self-associating tip complex protein Bsp22. This protein is immunogenic during infections by Bordetella bronchiseptica and could be used as a protective antigen to immunize mice against B. bronchiseptica challenge. Since low-pa
  • PMID 23690400
  • The Stimulated Innate Resistance Event in Bordetella pertussis Infection Is Dependent on Reactive Oxygen Species Production.
  • Zurita E, Moreno G, Errea A, Ormazabal M, Rumbo M, Hozbor D.SourceLaboratorio VacSal, Instituto de Biotecnología y Biología Molecular, Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, CONICET, La Plata, Buenos Aires, Argentina.
  • Infection and immunity.Infect Immun.2013 Jul;81(7):2371-8. doi: 10.1128/IAI.00336-13. Epub 2013 Apr 29.
  • The exacerbated induction of innate immune responses in airways can abrogate diverse lung infections by a phenomenon known as stimulated innate resistance (StIR). We recently demonstrated that the enhancement of innate response activation can efficiently impair Bordetella pertussis colonization in a
  • PMID 23630952


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関連記事infection」「Bordetella pertussis



  • n.
contagioninfectinfectious diseaseinfestationtransmissiontransmit

WordNet   license wordnet

「(medicine) the invasion of the body by pathogenic microorganisms and their multiplication which can lead to tissue damage and disease」

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「(phonetics) the alteration of a speech sound under the influence of a neighboring sound」

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「the pathological state resulting from the invasion of the body by pathogenic microorganisms」

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「(international law) illegality that taints or contaminates a ship or cargo rendering it liable to seizure」

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「moral corruption or contamination; "ambitious men are led astray by an infection that is almost unavoidable"」

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「an incident in which an infectious disease is transmitted」
contagion, transmission

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「〈U〉(病気の)伝染;感染 / 〈C〉伝染病」

Bordetella pertussis」


Bordetella pertussis
百日咳菌ボルデー・ジャングー菌 Bordet-Gengou bacillus


  • ボルデテラ属
  • グラム陰性桿菌(グラム陰性球桿菌)
  • 好気性
  • 百日咳の原因菌
  • 伝染性が強い
  • 不顕感染はまれ


  • 百日咳毒素:リンパ球増加、低血糖、気管上皮への付着 ← リンパ球増多症
  • アデニルシクラーゼ毒素:白血球走化能の抑制
  • 気管細胞毒素
  • 皮膚壊死毒素
  • 線維素性血球凝集素
  • リポポリサッカライド