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membranous tissue covering internal organs and other internal surfaces of the body (同)epithelial_tissue

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Pizzi M, Fassan M, Realdon S, Balistreri M, Battaglia G, Giacometti C, Zaninotto G, Zagonel V, De Boni M, Rugge M.SourceDepartment of Medical Diagnostic Sciences and Special Therapies, Surgical Pathology and Cytopathology Unit, University of Padova, 35100 Padova, Italy.
Human pathology.Hum Pathol.2012 Nov;43(11):1839-44. doi: 10.1016/j.humpath.2012.01.004. Epub 2012 Apr 20.
Barrett esophagus is the precancerous lesion leading to Barrett adenocarcinoma. The natural history of Barrett metaplasia and its neoplastic progression are still controversial. Anterior gradient 2 is up-regulated in both Barrett intestinal metaplasia and Barrett adenocarcinoma, but no information i
PMID 22521076

Prevention of Barrett Esophagus and Esophageal Adenocarcinoma by Smoothened Inhibitor in a Rat Model of Gastroesophageal Reflux Disease.

Gibson MK, Zaidi AH, Davison JM, Sanz AF, Hough B, Komatsu Y, Kosovec JE, Bhatt A, Malhotra U, Foxwell T, Rotoloni CL, Hoppo T, Jobe BA.Source*Department of Medicine, University of Pittsburgh, Pittsburgh, PA †Allegheny-Singer Research Institute, Western Pennsylvania Allegheny Health System, Pittsburgh, PA ‡Department of Pathology, University of Pittsburgh, Pittsburgh, PA §Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA ‖Roswell Park Cancer Institute, Buffalo, NY ¶Department of Surgery, The Western Pennsylvania Hospital, Western Pennsylvania Allegheny Health System, Pittsburgh, PA.
Annals of surgery.Ann Surg.2012 Oct 26. [Epub ahead of print]
BACKGROUND:: Activated hedgehog (Hh) pathway is associated with development of both Barrett esophagus (BE) and esophageal adenocarcinoma (EAC). We hypothesize that blockade of the Hh pathway with smoothened (Smo) inhibitor can prevent the development of BE/EAC in the Levrat model, in which induced g
PMID 23108119

Bile acid-induced expression of activation-induced cytidine deaminase during the development of Barrett's oesophageal adenocarcinoma.

Morita Shuko,Matsumoto Yuko,Okuyama Shunsuke,Ono Koh,Kitamura Yoko,Tomori Akihisa,Oyama Tsuneo,Amano Yuji,Kinoshita Yoshikazu,Chiba Tsutomu,Marusawa Hiroyuki
Carcinogenesis 32(11), 1706-1712, 2011-09-01
… The findings of the present study provide evidence of ectopic AID expression in Barrett's oesophagus and Barrett's oesophageal adenocarcinoma, a cancer that develops under chronic inflammatory conditions. …
NAID 120004874033