B-cell-specific transcription factor

B細胞特異的転写因子

関

B-cell-specific activator protein

WordNet

1. stated explicitly or in detail; "needed a specific amount"
2. a medicine that has a mitigating effect on a specific disease; "quinine is a specific for malaria"
3. (sometimes followed by `to'
4. being or affecting a disease produced by a particular microorganism or condition; used also of stains or dyes used in making microscope slides; "quinine is highly specific for malaria"; "a specific remedy"; "a specific stain is one having a specific affinity for particular structural elements"
5. relating to or distinguishing or constituting a taxonomic species; "specific characters"
6. be a contributing factor; "make things factor into a companys profitability"
7. any of the numbers (or symbols) that form a product when multiplied together
8. an independent variable in statistics
9. anything that contributes causally to a result; "a number of factors determined the outcome"
10. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
11. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
12. small room in which a monk or nun lives (同)cubicle
13. a device that delivers an electric current as the result of a chemical reaction (同)electric cell
14. a room where a prisoner is kept (同)jail cell, prison cell
15. (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
16. any small compartment; "the cells of a honeycomb"
17. a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
18. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
19. a concept whose truth can be proved; "scientific hypotheses are not facts"
20. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
21. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
22. (genetics) the organic process whereby the DNA sequence in a gene is copied into mRNA; the process whereby a base sequence of messenger RNA is synthesized on a template of complementary DNA
23. a sound or television recording (e.g., from a broadcast to a tape recording)
24. something written, especially copied from one medium to another, as a typewritten version of dictation (同)written text

PrepTutorEJDIC

1. 《名詞の前にのみ用いて》『特定の』,一定の・『明確な』,明白な・(そのものに)『特有の』,独特の《+『to』+『名』》・〈C〉(…の)特効薬《+『for』+『名』》・《複数形で》明細,細部(details)
2. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
3. (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
4. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
5. 〈U〉(…を)書き写す(書き直す)こと,(…の)転写,謄写《+of+名》 / 〈C〉写し(書き直し)[たもの] / 〈U〉〈C〉編曲[されたもの] / 〈U〉〈C〉(ラジオ・テレビの)録音(録画)

UpToDate Contents

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• 1. BおよびTリンパ球の正常な発生 normal b and t lymphocyte development
• 2. 結節性リンパ球優位型ホジキンリンパ腫の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of nodular lymphocyte predominant hodgkin lymphoma
• 3. 古典型ホジキンリンパ腫の疫学、病理学的特徴、および診断 epidemiology pathologic features and diagnosis of classical hodgkin lymphoma
• 4. 関節リウマチの病因 pathogenesis of rheumatoid arthritis
• 5. 前駆B細胞性急性リンパ芽球性白血病／リンパ腫の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of precursor b cell acute lymphoblastic leukemia lymphoma

English Journal

• Epigenetic and genetic alterations and their influence on gene regulation in chronic lymphocytic leukemia.

• Huang D1, Ovcharenko I2.
• BMC genomics.BMC Genomics.2017 Mar 16;18(1):236. doi: 10.1186/s12864-017-3617-6.
• PMID 28302063

• TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1.

• Jahn L1, Hombrink P1,2, Hagedoorn RS1, Kester MG1, van der Steen DM1, Rodriguez T3, Pentcheva-Hoang T3, de Ru AH4, Schoonakker MP1, Meeuwsen MH1, Griffioen M1, van Veelen PA4, Falkenburg JH1, Heemskerk MH1.
• Blood.Blood.2017 Mar 9;129(10):1284-1295. doi: 10.1182/blood-2016-09-737536. Epub 2017 Jan 4.
• PMID 28053195

• Tumor suppressors BTG1 and IKZF1 cooperate during mouse leukemia development and increase relapse risk in B-cell precursor acute lymphoblastic leukemia patients.

• Scheijen B1, Boer JM2, Marke R3, Tijchon E3, van Ingen Schenau D3, Waanders E4,5, van Emst L3, van der Meer LT3, Pieters R5, Escherich G6, Horstmann MA6, Sonneveld E7, Venn N8, Sutton R8, Dalla-Pozza L9, Kuiper RP4,5, Hoogerbrugge PM5, den Boer ML2, van Leeuwen FN3.
• Haematologica.Haematologica.2017 Mar;102(3):541-551. doi: 10.3324/haematol.2016.153023. Epub 2016 Dec 15.
• PMID 27979924

Japanese Journal

• B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs

• KAMIO T
• Blood 102, 3317-3322, 2003
• NAID 30022496338

• B細胞特異的転写因子BACH2によるBCL-2関連遺伝子A1の発現抑制機構

• 丹代(山田) 諭,佐藤 秀子,金崎 里香,土岐 力,五十嵐 和彦,伊藤 悦朗
• 弘前醫學 54(1), 8-20, 2002-00-00
• NAID 110004771364

• B細胞特異的転写因子BACH2の標的遺伝子の同定

• 佐藤 秀子,佐々木 伸也,金崎 里香,土岐 力,伊藤 悦朗
• 弘前醫學 53(2), 73-81, 2001-00-00
• NAID 110004771353

Related Links

• The B-Cell Specific Transcription Factor, Oct-2, Promotes ...

The B-Cell Specific Transcription Factor, Oct-2, Promotes Epstein-Barr Virus Latency by Inhibiting the Viral Immediate-Early Protein, BZLF1 Amanda R. Robinson1,2, Swee Sen Kwek1, Shannon C. Kenney1,3* 1Department of ...

• Transcription factors drive B cell development - ScienceDirect

The Ets family transcription factor PU.1 (encoded by sfpi-1 in mice) is an important regulator of hematopoietic cell fates and of B-cell-specific transcription. Past studies reported that independently generated mouse lines that had ...

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★リンクテーブル★

リンク元	「B-cell-specific activator protein」「B細胞特異的転写因子」
関連記事	「specific」「B」「fact」「factor」「transcription factor」

「B-cell-specific activator protein」

　　[★]

B細胞特異的活性化タンパク質、B細胞特異的アクチベータータンパク質

関

B-cell-specific transcription factor、BSAP

「B細胞特異的転写因子」

　　[★]

英

B-cell-specific transcription factor

「specific」

　　[★]

• adj.

• (～に関して)明確な、はっきりとした(exact precise)、具体的な(in, about)
• (比較)(限定)特定の(particular)、一定の(⇔general)
• (～に)特有の、独特の(to)
• (比較)(医学)(～に)渡航のある(for)。特殊な
• (生物)(生物)種の
• 医学)特異の
• (物理)比の。物質固有の。単位質量・長さ・面積・容積で

n.

関

specifically、specificity

　 　 　 　 　 　

「B」

　　[★]

• 気管分岐部下緑
• 補体のalternative pathwayに関わる蛋白質

• Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する

　 　

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「transcription factor」

　　[★]

• 転写制御因子、転写因子

関

TF、transcriptional regulator、transcriptional regulatory element