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- 1. 成人における単極性うつ病：難治性うつ病の治療 unipolar depression in adults treatment of resistant depression
- 2. リウマチ性疾患に対する補完・代替療法 complementary and alternative remedies for rheumatic disorders
- 3. アルコール性脂肪性肝疾患およびアルコール性肝硬変の予後および治療 prognosis and management of alcoholic fatty liver disease and alcoholic cirrhosis
- 4. Peeling skin syndrome
- 5. 統合失調症に対する薬物療法：持効性抗精神病薬注射製剤 pharmacotherapy for schizophrenia long acting injectable antipsychotic drugs
English Journal
- One carbon metabolism in pregnancy: Impact on maternal, fetal and neonatal health.
- Kalhan SC1.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2016 Nov 5;435:48-60. doi: 10.1016/j.mce.2016.06.006. Epub 2016 Jun 4.
- One carbon metabolism or methyl transfer, a crucial component of metabolism in all cells and tissues, supports the critical function of synthesis of purines, thymidylate and methylation via multiple methyl transferases driven by the ubiquitous methyl donor s-adenosylmethionine. Serine is the primary
- PMID 27267668
- Structure and dynamics of H. pylori 98-10 C5-cytosine specific DNA methyltransferase in complex with S-adenosyl-l-methionine and DNA.
- Singh S1, Tanneeru K, Guruprasad L.
- Molecular bioSystems.Mol Biosyst.2016 Oct 20;12(10):3111-23. doi: 10.1039/c6mb00306k. Epub 2016 Jul 29.
- Helicobacter pylori is a Gram-negative bacterium that inhabits the human gastrointestinal tract, and some strains of this bacterium cause gastric ulcers and cancer. DNA methyltransferases (MTases) are promising drug targets for the treatment of cancer and other diseases that are also caused by epige
- PMID 27470658
- The effect of increasing concentrations of dl-methionine and 2-hydroxy-4-(methylthio) butanoic acid on hepatic genes controlling methionine regeneration and gluconeogenesis.
- Zhang Q1, Bertics SJ1, Luchini ND2, White HM3.
- Journal of dairy science.J Dairy Sci.2016 Oct;99(10):8451-60. doi: 10.3168/jds.2016-11312. Epub 2016 Jul 27.
- Metabolizable methionine (Met) concentrations can be increased by feeding rumen-protected dl-Met or the isopropyl ester of 2-hydroxy-4-(methylthio) butanoic acid (HMBi). Hepatic responses to increasing concentrations of metabolizable Met as a result of supplementation of different Met sources have n
- PMID 27474977
Japanese Journal
- Morphological Effects of Sinefungin, an Inhibitor of S-Adenosylmethionine-Dependent Methyltransferases, on Anabaena sp. PCC 7120
- FUJITA HIRONORI,SYONO KUNIHIKO,MACHIDA YASUNORI,KAWAGUCHI MASAYOSHI
- Microbes and environments 23(4), 346-349, 2008-12
- … The defects probably result from depletion of S-adenosylmethionine (AdoMet), because they were rescued by the application of methionine, an AdoMet precursor, and because sinefungin, a strong inhibitor of AdoMet-dependent methyltransferases, caused morphological abnormalities in wild-type Anabaena similar to those of the mutant. … AdoMet-dependent methylation is involved in the spatial regulation of cell polarity in Anabaena. …
- NAID 110007005108
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Related Pictures
★リンクテーブル★
| リンク元 | 「S-アデノシルメチオニン」「S-adenosyl-L-methionine」「S-アデノシル-L-メチオニン」「ademetionine」 |
「S-アデノシルメチオニン」
- 英
- S-adenosylmethionine, SAM
- 同
- 活性メチオニン active methionine
- 関
- アデノシルメチオニン ademetionine AdoMet、S-adenosyl-L-methionine
- メチル基供与体となる体内物質