ATP-ADP translocator

ATP-ADPトランスロケータ

WordNet

1. the 1st letter of the Roman alphabet (同)a
2. the blood group whose red cells carry the A antigen (同)type_A, group A
3. in the Christian era; used before dates after the supposed year Christ was born; "in AD 200" (同)A.D., anno_Domini

PrepTutorEJDIC

1. answer / ampere

UpToDate Contents

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• 1. 拡張能障害の細胞学的機序 cellular mechanisms of diastolic dysfunction
• 2. 運動生理学 exercise physiology
• 3. 筋肉におけるエネルギー代謝 energy metabolism in muscle
• 4. 心不全における骨格筋機能低下および運動耐容能低下 skeletal muscle dysfunction and exercise intolerance in heart failure
• 5. 虚血性脳卒中の病態生理 pathophysiology of ischemic stroke

English Journal

• Deficiency in the mouse mitochondrial adenine nucleotide translocator isoform 2 gene is associated with cardiac noncompaction.

• Kokoszka JE1, Waymire KG2, Flierl A3, Sweeney KM4, Angelin A4, MacGregor GR2, Wallace DC5.
• Biochimica et biophysica acta.Biochim Biophys Acta.2016 Aug;1857(8):1203-12. doi: 10.1016/j.bbabio.2016.03.026. Epub 2016 Apr 24.
• The mouse fetal and adult hearts express two adenine nucleotide translocator (ANT) isoform genes. The predominant isoform is the heart-muscle-brain ANT-isoform gene 1 (Ant1) while the other is the systemic Ant2 gene. Genetic inactivation of the Ant1 gene does not impair fetal development but results
• PMID 27048932

• Misfolding of mutant adenine nucleotide translocase in yeast supports a novel mechanism of Ant1-induced muscle diseases.

• Liu Y1, Wang X1, Chen XJ2.
• Molecular biology of the cell.Mol Biol Cell.2015 Jun 1;26(11):1985-94. doi: 10.1091/mbc.E15-01-0030. Epub 2015 Apr 1.
• Approximately one-third of proteins in the cell reside in the membrane. Mutations in membrane proteins can induce conformational changes and expose nonnative polar domains/residues to the lipid environment. The molecular effect of the resulting membrane stress is poorly defined. Adenine nucleotide t
• PMID 25833713

• Effects of standardized extract of Ginkgo biloba leaves EGb761 on mitochondrial functions: mechanism(s) of action and dependence on the source of mitochondria and respiratory substrate.

• Baliutyte G1, Trumbeckaite S, Baniene R, Borutaite V, Toleikis A.
• Journal of bioenergetics and biomembranes.J Bioenerg Biomembr.2014 Dec;46(6):493-501. doi: 10.1007/s10863-014-9590-8. Epub 2014 Nov 14.
• In this work, the effects of standardized dry extract of Ginkgo biloba leaves, EGb761, on the respiration of rat heart and liver mitochondria were investigated. We revealed uncoupling of oxidative phosphorylation in rat heart mitochondria by EGb761 which was not observed in liver mitochondria respir
• PMID 25395298

Japanese Journal

• 8 ボンクレキン酸の全合成(口頭発表の部)

• 天然有機化合物討論会講演要旨集 (45), 43-48, 2003-09-01
• NAID 110006682267

• 136(P-88) ボンクレキン酸の合成研究(ポスター発表の部)

• 天然有機化合物討論会講演要旨集 (42), 811-816, 2000-10-01
• NAID 110006682038

• ^1AP-2 Enhances Sp1-Dependent Activation of the Growth-Regulated Human ATP/ADP Translocator^1

• The journal of biochemistry 126(1), 130-136, 1999-07-01
• NAID 10005856625

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★リンクテーブル★

リンク元	「ATP-ADPトランスロケータ」
関連記事	「AT」「ADP」「translocator」「ATP」「A」

「ATP-ADPトランスロケータ」

　　[★]

英

ATP-ADP translocator

同

アデニンジヌクレオチドトランスロカーゼ

関

ミトコンドリア

機能

• ADP^3-をマトリクスに取り込み、ATP^4-を膜間部に出す

駆動力

• 膜電位

• 膜間部が正電位

「AT」

　　[★]

• 無酸素性作業閾値 anaerobic threshold
• 毛細血管拡張性運動失調症 ataxia telangiectasia
• アンチトロンビン antithrombin
• 加速時間 acceleration time

「ADP」

　　[★]

• アデノシン二リン酸 adenosine diphosphate adenosine 5'-diphosphate
• 5-aminolevulinic acid dehydratase porphyria
• 母指内転筋 adductor pollicis

「translocator」

　　[★]

• 輸送体、トランスロケーター

関

transport protein、transporter、transporter protein

「ATP」

　　[★] アデノシン三リン酸 アデノシン3リン酸 adenosine triphosphate adenosine 5'-triphosphate

「A」

　　[★]

• アデニン adenine
• アデノシン adenosine
• アラニン alanine